Protein: RPC5
DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit C5) (DNA-directed RNA polymerase III 37 kDa polypeptide) (RNA polymerase III subunit C37)

Gene: RPC5, RPC37
Organism: Saccharomyces cerevisiae S288C
Interactions: 59
UniProt ID: P36121

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005666 - RNA polymerase III complex
GO:0006383 - transcription by RNA polymerase III
GO:0006384 - transcription initiation at RNA polymerase III promoter
GO:0006386 - termination of RNA polymerase III transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

647083

RPC2
DNA-directed RNA polymerase III subunit RPC2

7

3

Small-scale

0.958

High

748124

RPC6
DNA-directed RNA polymerase III subunit RPC6

5

1

Small-scale

0.919

High

459073

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

5

3

Small-scale

0.919

High

674405

RPC4
DNA-directed RNA polymerase III subunit RPC4

7

0

Small-scale

0.915

High

402213

RPC1
DNA-directed RNA polymerase III subunit RPC1

6

3

Small-scale

0.730

High

776295

RPC8
DNA-directed RNA polymerase III subunit RPC8

5

2

High-throughput

0.714

High

734935

RPC3
DNA-directed RNA polymerase III subunit RPC3

4

1

High-throughput

0.691

High

781682

RPC9
DNA-directed RNA polymerase III subunit RPC9

3

0

High-throughput

0.622

High

594320

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

Small-scale

0.618

High

645048

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

1

High-throughput

0.618

High

781690

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

3

High-throughput

0.618

High

781681

TFC5
Transcription factor TFIIIB component B''

3

1

Small-scale

0.585

High

708716

TF3B
Transcription factor IIIB 70 kDa subunit

2

2

High-throughput

0.584

High

609187

RPC7
DNA-directed RNA polymerase III subunit RPC7

2

0

High-throughput

0.576

High

632159

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

2

1

Small-scale

0.566

High

781678

MAF1
Repressor of RNA polymerase III transcription MAF1

1

1

High-throughput

0.515

High

781694

YD144
Uncharacterized protein YDL144C

1

0

High-throughput

0.493

High

781695

RRP44
Exosome complex exonuclease DIS3

1

0

High-throughput

0.493

High

781679

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

381070

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

381490

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

382033

H4
Histone H4

1

1

High-throughput

0.479

High

419406

H2A1
Histone H2A.1

1

1

High-throughput

0.479

High

419700

H2A2
Histone H2A.2

1

1

High-throughput

0.479

High

632252

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.479

High

632337

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

2

High-throughput

0.479

High

699997

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

2

High-throughput

0.479

High

706801

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

781676

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.479

High

781689

SEN1
Helicase SEN1

1

1

Small-scale

0.479

High

364474

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.458

High

439313

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

448302

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

561464

TBP
TATA-box-binding protein

1

0

High-throughput

0.458

High

745703

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

781677

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

781684

CTH2
mRNA decay factor CTH2

1

0

High-throughput

0.458

High

781685

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.458

High

781686

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

781687

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

781688

H3
Histone H3

1

0

High-throughput

0.458

High

781692

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

781693

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.458

High

781696

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

781697

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

523626

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526414

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

547785

NHP6A
Non-histone chromosomal protein 6A

1

2

High-throughput

0.445

High

544487

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

781675

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

510387

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.407

High

781691

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

3

High-throughput

0.407

High

449114

CALM
Calmodulin

1

0

Small-scale

0.292

High

736482

MDHP
Malate dehydrogenase, peroxisomal

1

0

High-throughput

0.269

Low

781680

FAR7
Factor arrest protein 7

1

0

High-throughput

0.269

Low

646656

VPS15
Serine/threonine-protein kinase VPS15

1

0

High-throughput

0.249

Low

747211

RM06
Large ribosomal subunit protein uL6m

1

0

High-throughput

0.249

Low

781683

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.249

Low

752129

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025