Protein: RPC6
DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (C34) (DNA-directed RNA polymerase III 36 kDa polypeptide)

Gene: RPC6, RPC34
Organism: Saccharomyces cerevisiae S288C
Interactions: 73
UniProt ID: P32910

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

734908

RPC3
DNA-directed RNA polymerase III subunit RPC3

12

1

Small-scale

0.981

High

647067

RPC2
DNA-directed RNA polymerase III subunit RPC2

9

2

Small-scale

0.968

High

402207

RPC1
DNA-directed RNA polymerase III subunit RPC1

7

1

Small-scale

0.962

High

708702

TF3B
Transcription factor IIIB 70 kDa subunit

6

4

Small-scale

0.935

High

748135

MAF1
Repressor of RNA polymerase III transcription MAF1

5

1

Small-scale

0.924

High

748124

RPC5
DNA-directed RNA polymerase III subunit RPC5

5

1

Small-scale

0.919

High

609184

RPC7
DNA-directed RNA polymerase III subunit RPC7

7

0

Small-scale

0.913

High

459060

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

6

1

Small-scale

0.732

High

632150

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

5

1

Small-scale

0.713

High

748123

RPC8
DNA-directed RNA polymerase III subunit RPC8

4

1

High-throughput

0.694

High

748138

RPC9
DNA-directed RNA polymerase III subunit RPC9

5

0

Small-scale

0.688

High

674401

RPC4
DNA-directed RNA polymerase III subunit RPC4

5

0

Small-scale

0.684

High

632329

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

3

1

Small-scale

0.676

High

644897

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

2

High-throughput

0.665

High

748148

RPC10
DNA-directed RNA polymerase III subunit RPC10

3

1

High-throughput

0.662

High

544294

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.601

High

632245

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

2

1

High-throughput

0.601

High

699990

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

2

1

High-throughput

0.601

High

547864

NHP6B
Non-histone chromosomal protein 6B

2

1

High-throughput

0.588

High

748133

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

523467

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.536

High

748136

RSC8
Chromatin structure-remodeling complex protein RSC8

1

0

High-throughput

0.513

High

748119

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

0

High-throughput

0.493

High

748125

STU1
Protein STU1

1

0

High-throughput

0.493

High

748147

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.493

High

748120

TFC4
Transcription factor tau 131 kDa subunit

1

0

Small-scale

0.480

High

381041

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

381469

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

419393

H2A1
Histone H2A.1

1

2

High-throughput

0.479

High

419670

H2A2
Histone H2A.2

1

2

High-throughput

0.479

High

561451

TBP
TATA-box-binding protein

1

1

High-throughput

0.479

High

645040

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

1

High-throughput

0.479

High

706624

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

748134

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.479

High

748137

TFC5
Transcription factor TFIIIB component B''

1

1

High-throughput

0.479

High

748143

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

748146

SEN1
Helicase SEN1

1

1

Small-scale

0.479

High

381988

H4
Histone H4

1

0

High-throughput

0.458

High

745682

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

748129

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.458

High

748130

SPP41
Protein SPP41

1

0

High-throughput

0.458

High

748132

EXO1
Exodeoxyribonuclease 1

1

0

High-throughput

0.458

High

748142

RBG2
Ribosome-interacting GTPase 2

1

0

High-throughput

0.458

High

748144

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

748150

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

748151

SGO1
Shugoshin

1

0

High-throughput

0.458

High

748152

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.458

High

748153

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

748155

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

392474

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

510342

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.445

High

526271

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

547781

NHP6A
Non-histone chromosomal protein 6A

1

1

High-throughput

0.445

High

579103

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.445

High

670516

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

675854

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

741254

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

742808

HSP79
Heat shock protein homolog SSE2

1

5

High-throughput

0.445

High

748122

IXR1
Intrastrand cross-link recognition protein

1

2

High-throughput

0.445

High

748128

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

748139

DPH4
Diphthamide biosynthesis protein 4

1

1

High-throughput

0.445

High

748127

YPT31
GTP-binding protein YPT31/YPT8

1

0

High-throughput

0.438

High

394400

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

570798

ABF1
ARS-binding factor 1

1

0

High-throughput

0.426

High

748121

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

748140

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.426

High

748141

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

748149

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.426

High

748154

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

748126

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.238

Low

748145

YD413
Putative uncharacterized protein YDR413C

1

0

High-throughput

0.238

Low

748131

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025