Protein: RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (ABC27) (DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide)

Gene: RPAB1, RPB5
Organism: Saccharomyces cerevisiae S288C
Interactions: 140
UniProt ID: P20434

Gene Ontology (top 5):
GO:0001172 - RNA-templated transcription
GO:0003677 - DNA binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

401880

RPB1
DNA-directed RNA polymerase II subunit RPB1

17

15

Small-scale

0.982

High

534211

RPA1
DNA-directed RNA polymerase I subunit RPA190

13

15

Small-scale

0.981

High

632135

RPB9
DNA-directed RNA polymerase II subunit RPB9

9

7

Small-scale

0.966

High

402188

RPC1
DNA-directed RNA polymerase III subunit RPC1

7

15

Small-scale

0.960

High

632143

RPA12
DNA-directed RNA polymerase I subunit RPA12

4

7

High-throughput

0.896

High

632168

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

3

1

Small-scale

0.827

High

454556

TFS2
Transcription elongation factor S-II

2

2

High-throughput

0.789

High

594176

RPB3
DNA-directed RNA polymerase II subunit RPB3

22

6

Small-scale

0.765

High

632154

RPB7
DNA-directed RNA polymerase II subunit RPB7

11

4

Small-scale

0.753

High

632055

RPB4
DNA-directed RNA polymerase II subunit RPB4

11

1

Small-scale

0.752

High

470457

RPB2
DNA-directed RNA polymerase II subunit RPB2

9

10

Small-scale

0.752

High

632123

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

11

1

Small-scale

0.752

High

632122

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

10

2

Small-scale

0.749

High

459014

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

7

6

Small-scale

0.746

High

632174

T2FB
Transcription initiation factor IIF subunit beta

7

2

Small-scale

0.745

High

632126

RPC2
DNA-directed RNA polymerase III subunit RPC2

7

10

Small-scale

0.741

High

632165

RPB11
DNA-directed RNA polymerase II subunit RPB11

7

3

Small-scale

0.737

High

632124

RPA2
DNA-directed RNA polymerase I subunit RPA135

6

10

High-throughput

0.735

High

632209

RPC10
DNA-directed RNA polymerase III subunit RPC10

2

7

Small-scale

0.730

High

632125

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

6

2

Small-scale

0.721

High

632178

RPA43
DNA-directed RNA polymerase I subunit RPA43

5

1

Small-scale

0.714

High

632150

RPC6
DNA-directed RNA polymerase III subunit RPC6

5

1

Small-scale

0.713

High

632157

RPC8
DNA-directed RNA polymerase III subunit RPC8

5

4

Small-scale

0.713

High

632156

TAF14
Transcription initiation factor TFIID subunit 14

6

0

Small-scale

0.700

High

632171

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

5

1

Small-scale

0.697

High

632201

RPA49
DNA-directed RNA polymerase I subunit RPA49

4

1

High-throughput

0.694

High

632176

BUD27
Bud site selection protein 27

5

0

Small-scale

0.688

High

632136

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

4

3

Small-scale

0.684

High

632134

SPT5
Transcription elongation factor SPT5

4

1

Small-scale

0.683

High

632142

RPC3
DNA-directed RNA polymerase III subunit RPC3

4

1

Small-scale

0.682

High

632173

T2FA
Transcription initiation factor IIF subunit alpha

5

0

Small-scale

0.676

High

632121

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

2

High-throughput

0.665

High

632220

IWR1
RNA polymerase II nuclear localization protein IWR1

4

0

Small-scale

0.661

High

632129

RPC4
DNA-directed RNA polymerase III subunit RPC4

4

0

Small-scale

0.655

High

632151

SPT4
Transcription elongation factor SPT4

4

0

Small-scale

0.649

High

632180

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

3

1

Small-scale

0.640

High

632144

SPT16
FACT complex subunit SPT16

3

0

High-throughput

0.630

High

632167

RSP5
E3 ubiquitin-protein ligase RSP5

2

3

High-throughput

0.628

High

632189

PFD6
Prefoldin subunit 6

2

1

High-throughput

0.628

High

632181

RPA34
DNA-directed RNA polymerase I subunit RPA34

3

0

High-throughput

0.622

High

632183

RPC9
DNA-directed RNA polymerase III subunit RPC9

3

0

Small-scale

0.617

High

632138

TF2B
Transcription initiation factor IIB

2

2

High-throughput

0.614

High

632218

ASR1
Alcohol-sensitive RING finger protein 1

3

0

Small-scale

0.613

High

632184

GPN1
GPN-loop GTPase 1

3

3

Small-scale

0.585

High

632139

TF3B
Transcription factor IIIB 70 kDa subunit

2

2

High-throughput

0.584

High

632211

POB3
FACT complex subunit POB3

2

1

High-throughput

0.584

High

632188

RPA14
DNA-directed RNA polymerase I subunit RPA14

2

0

High-throughput

0.576

High

632159

RPC5
DNA-directed RNA polymerase III subunit RPC5

2

1

Small-scale

0.566

High

632172

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

609172

RPC7
DNA-directed RNA polymerase III subunit RPC7

2

0

Small-scale

0.542

High

547757

NHP6A
Non-histone chromosomal protein 6A

1

1

High-throughput

0.541

High

632141

XPO1
Exportin-1

1

3

High-throughput

0.536

High

632155

SPT7
SAGA complex subunit SPT7

1

2

High-throughput

0.536

High

632191

NRD1
Protein NRD1

1

1

Small-scale

0.536

High

632205

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

2

Small-scale

0.527

High

632166

IFH1
Protein IFH1

1

0

High-throughput

0.518

High

632196

ERG13
Hydroxymethylglutaryl-CoA synthase

1

0

High-throughput

0.518

High

632215

IWS1
Transcription factor SPN1

1

0

High-throughput

0.518

High

441325

KAPB
cAMP-dependent protein kinase type 2

1

0

High-throughput

0.513

High

632175

ELP2
Elongator complex protein 2

1

0

Small-scale

0.513

High

584340

GCN2
eIF-2-alpha kinase GCN2

1

1

High-throughput

0.501

High

632170

RAD26
DNA repair and recombination protein RAD26

1

1

Small-scale

0.501

High

632163

KSP1
Serine/threonine-protein kinase KSP1

1

0

High-throughput

0.480

High

632206

STE20
Serine/threonine-protein kinase STE20

1

0

High-throughput

0.480

High

380958

H2B1
Histone H2B.1

1

3

High-throughput

0.479

High

381393

H2B2
Histone H2B.2

1

3

High-throughput

0.479

High

381862

H4
Histone H4

1

1

High-throughput

0.479

High

419353

H2A1
Histone H2A.1

1

1

High-throughput

0.479

High

419590

H2A2
Histone H2A.2

1

1

High-throughput

0.479

High

434814

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

561415

TBP
TATA-box-binding protein

1

2

High-throughput

0.479

High

632127

SPT6
Transcription elongation factor SPT6

1

1

High-throughput

0.479

High

632169

ATAD2
ATPase histone chaperone YTA7

1

1

Small-scale

0.479

High

632177

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.479

High

632179

TFC5
Transcription factor TFIIIB component B''

1

1

High-throughput

0.479

High

632195

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.479

High

632199

SEN1
Helicase SEN1

1

1

High-throughput

0.479

High

632200

CDC14
Tyrosine-protein phosphatase CDC14

1

1

High-throughput

0.479

High

632202

MCE1
mRNA-capping enzyme subunit alpha

1

1

High-throughput

0.479

High

632207

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.479

High

632212

HRQ1
ATP-dependent helicase HRQ1

1

2

Small-scale

0.479

High

149577

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

436314

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

441698

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

512250

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

632128

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

632130

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

632131

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

632132

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.458

High

632133

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

632146

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

Small-scale

0.458

High

632148

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

632160

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

632190

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

0

High-throughput

0.458

High

632192

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

1

0

Small-scale

0.458

High

632193

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

632197

H3
Histone H3

1

0

Small-scale

0.458

High

632198

RL34A
Large ribosomal subunit protein eL34A

1

0

High-throughput

0.458

High

632203

NOP3
Serine/arginine

1

0

Small-scale

0.458

High

632208

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

632213

RBS1
RNA-binding suppressor of PAS kinase protein 1

1

0

Small-scale

0.458

High

632214

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

632217

CDC73
Cell division control protein 73

1

0

High-throughput

0.458

High

632221

SGO1
Shugoshin

1

0

High-throughput

0.458

High

632223

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

632224

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

543782

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

619397

MED14
Mediator of RNA polymerase II transcription subunit 14

1

1

Small-scale

0.445

High

632147

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

632187

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

1

High-throughput

0.445

High

632140

RENT1
ATP-dependent helicase NAM7

1

1

Small-scale

0.437

High

632164

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

632204

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

632216

GPN3
GPN-loop GTPase 3

1

3

Small-scale

0.437

High

632145

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

Small-scale

0.426

High

578824

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.407

High

632137

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.282

High

632194

ERG5
C-22 sterol desaturase ERG5

1

0

High-throughput

0.282

High

148858

CET1
mRNA-capping enzyme subunit beta

1

0

High-throughput

0.249

Low

383512

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

433440

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

435765

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

454867

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

502843

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504032

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

512811

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

514449

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

632149

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

632153

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

632158

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

632161

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

632182

NET1
Nucleolar protein NET1

1

0

High-throughput

0.249

Low

632185

IML1
Vacuolar membrane-associated protein IML1

1

0

High-throughput

0.249

Low

632186

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

632210

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.249

Low

632219

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

632222

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

632162

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.238

Low

632152

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025