Protein: MOT3
Transcriptional activator/repressor MOT3 (Hypoxic gene repressor protein 7) (Modulator of transcription protein 3)

Gene: MOT3
Organism: Saccharomyces cerevisiae S288C
Interactions: 60
UniProt ID: P54785

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

393160

HSP82
ATP-dependent molecular chaperone HSP82

4

0

High-throughput

0.648

High

932272

MOT3
Transcriptional activator/repressor MOT3

3

0

Small-scale

0.630

High

921149

H1
Histone H1

2

0

High-throughput

0.583

High

382270

H4
Histone H4

2

0

High-throughput

0.547

High

932273

H3
Histone H3

2

0

High-throughput

0.547

High

917348

ROG1
Putative lipase ROG1

1

0

High-throughput

0.486

High

509676

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

577568

CYC8
General transcriptional corepressor CYC8

1

0

Small-scale

0.480

High

598426

TUP1
General transcriptional corepressor TUP1

1

0

Small-scale

0.480

High

649999

SIN3
Transcriptional regulatory protein SIN3

1

0

Small-scale

0.480

High

751178

BCK2
Protein BCK2

1

0

Small-scale

0.460

High

433785

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

436104

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

448325

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

455202

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

664331

SSD1
Protein SSD1

1

0

High-throughput

0.458

High

707884

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

741056

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

763962

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

808736

ITS3
Phosphatidylinositol 4-phosphate 5-kinase MSS4

1

0

High-throughput

0.458

High

808881

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

817682

DOT6
Transcriptional regulatory protein DOT6

1

0

High-throughput

0.458

High

874463

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

918566

ART5
Arrestin-related trafficking adapter 5

1

0

High-throughput

0.458

High

932275

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

932277

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

932279

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

932283

ECM22
Sterol regulatory element-binding protein ECM22

1

0

Small-scale

0.458

High

932285

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

743120

STH1
Nuclear protein STH1/NPS1

1

1

High-throughput

0.445

High

865364

YJ12B
Transposon Ty1-JR2 Gag-Pol polyprotein

1

1

High-throughput

0.445

High

792904

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

803830

BCD1
Box C/D snoRNA protein 1

1

0

High-throughput

0.438

High

932282

CIAO1
Cytosolic iron-sulfur protein assembly protein 1

1

0

High-throughput

0.438

High

932286

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

1

High-throughput

0.437

High

381591

H2B2
Histone H2B.2

1

0

High-throughput

0.426

High

545883

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

561508

TBP
TATA-box-binding protein

1

0

High-throughput

0.426

High

742162

HSP7F
Heat shock protein homolog SSE1

1

0

High-throughput

0.426

High

794202

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.426

High

803997

RSC30
Chromatin structure-remodeling complex protein RSC30

1

0

High-throughput

0.426

High

850553

RSC8
Chromatin structure-remodeling complex protein RSC8

1

0

High-throughput

0.426

High

917395

ITC1
Imitation switch two complex protein 1

1

0

High-throughput

0.426

High

932274

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

932278

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.426

High

932287

H2AZ
Histone H2A.Z

1

0

High-throughput

0.426

High

736815

BIOB
Biotin synthase, mitochondrial

1

0

High-throughput

0.265

Low

797772

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.265

Low

919652

SAY1
Steryl acetyl hydrolase 1

1

0

High-throughput

0.265

Low

932280

TMN2
Transmembrane 9 superfamily member 2

1

0

High-throughput

0.265

Low

932284

ZEO1
Protein ZEO1

1

0

High-throughput

0.265

Low

510719

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.249

Low

558827

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

826355

INP51
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51

1

0

High-throughput

0.249

Low

932276

YD239
Uncharacterized protein YDR239C

1

0

High-throughput

0.249

Low

932281

PAL1
Protein PAL1

1

0

High-throughput

0.249

Low

504822

YJ27A
Putative uncharacterized protein YJL127W-A

1

0

High-throughput

0.238

Low

752595

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

864306

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025