HitPredict

Interactor 1: A0A0S2Z4E4 (A0A0S2Z4E4)
NCK adaptor protein 1 isoform 3
Gene: NCK1

Interactor 2: EFS (O43281)
Embryonal Fyn-associated substrate (hEFS) (Cas scaffolding protein family member 3)
Gene: EFS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	26871637
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 244 Hs			1 561
+	Hs
		3132 A0A0S2Z4D7_HUMAN (1-132): 1.7e-42: 144: 100.00		EFS_HUMAN (1-561): 3.37e-71: 239: 100.00
+	Hs
		199495 ABL1_HUMAN (112-225): 3.4e-30: 120: 26.62		EFS_HUMAN (1-561): 3.37e-71: 239: 100.00
+	Hs
		91474 E7ERP6_HUMAN (1-76): 3.96e-33: 117: 78.95		EFS_HUMAN (1-561): 3.37e-71: 239: 100.00
+	Hs
		199501 NCK1_HUMAN (1-145): 2.8e-22: 95.7: 91.72		EFS_HUMAN (1-561): 3.37e-71: 239: 100.00
+	Hs
		199489 NCK2_HUMAN (1-196): 5.35e-18: 83.8: 48.29		EFS_HUMAN (1-561): 3.37e-71: 239: 100.00
+	Hs
		337474 ABL1_HUMAN (112-225): 3.4e-30: 120: 26.62		CASL_HUMAN (6-336): 2.64e-31: 131: 24.93
+	Hs
		985955 PTN11_HUMAN (144-244): 6.72e-27: 110: 32.04		CASL_HUMAN (6-336): 2.64e-31: 131: 24.93
+	Hs
		782781 CSK_HUMAN (69-238): 1.25e-33: 127: 20.23		ACK1_HUMAN (9-484): 1.17e-23: 107: 14.85
+	Hs
		557691 NCK1_HUMAN (1-145): 2.8e-22: 95.7: 91.72		CASL_HUMAN (6-336): 2.64e-31: 131: 24.93
+	Hs
		789093 ABL2_HUMAN (112-225): 4.09e-31: 122: 27.34		CASS4_HUMAN (379-557): 1.65e-20: 97.9: 19.89
+	Mm
		222878 NCK1_MOUSE (1-145): 3.16e-22: 95.7: 90.35		ACK1_MOUSE (11-484): 7.98e-29: 124: 15.31
+	Hs
		557740 NCK1_HUMAN (1-145): 2.8e-22: 95.7: 91.72		MINK1_HUMAN (48-378): 5.94e-26: 115: 14.67
+	Hs
		337335 ABL1_HUMAN (112-225): 3.4e-30: 120: 26.62		MUC1_HUMAN (63-481): 6.08e-16: 83.6: 11.37
+	Hs
		557670 NCK1_HUMAN (1-145): 2.8e-22: 95.7: 91.72		ACK1_HUMAN (9-484): 1.17e-23: 107: 14.85
+	Hs
		337411 ABL1_HUMAN (112-225): 3.4e-30: 120: 26.62		BCAR1_HUMAN (7-431): 2.78e-12: 71.7: 21.40
+	Hs
		203208 NCK1_HUMAN (1-145): 2.8e-22: 95.7: 91.72		SYNJ1_HUMAN (95-472): 7.88e-19: 92.8: 13.96
+	Hs
		882258 PTN11_HUMAN (144-244): 6.72e-27: 110: 32.04		BCAR1_HUMAN (7-431): 2.78e-12: 71.7: 21.40
+	Rn
		783508 PTN11_RAT (144-244): 6.78e-27: 110: 32.04		BCAR1_RAT (6-431): 4.77e-12: 70.9: 20.23
+	Hs
		557645 NCK1_HUMAN (1-145): 2.8e-22: 95.7: 91.72		BCAR1_HUMAN (7-431): 2.78e-12: 71.7: 21.40
+	Rn
		1144371 P85A_RAT (89-243): 1.03e-21: 95.3: 17.20		BCAR1_RAT (6-431): 4.77e-12: 70.9: 20.23