HitPredict

Interactor 1: UBC2 (P06104)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Radiation sensitivity protein 6) (Ubiquitin carrier protein UBC2) (Ubiquitin-protein ligase UBC2)
Gene: RAD6

Interactor 2: UBA4 (P38820)
Adenylyltransferase and sulfurtransferase UBA4 (Needs CLA4 to survive protein 3) (Ubiquitin-like protein activator 4) [Includes: Adenylyltransferase UBA4 (EC 2.7.7.-); Sulfurtransferase UBA4 (EC 2.8.1.-)]
Gene: UBA4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9287349
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 172 Sc			1 440
+	Hs
		982316 UB2D2_HUMAN (4-150): 2.35e-81: 238: 38.10		UBA5_HUMAN (4-275): 9.13e-65: 215: 20.67
+	Hs
		982256 UB2D2_HUMAN (4-150): 2.35e-81: 238: 38.10		UBA3_HUMAN (1-230): 6.66e-62: 209: 23.58
+	Sp
		314596 UBC4_SCHPO (4-149): 1.69e-79: 234: 40.41		UBA1_SCHPO (43-358): 2.12e-57: 205: 15.17
+	Hs
		1381215 UB2E3_HUMAN (3-150): 3.05e-74: 223: 33.11		SAE2_HUMAN (51-226): 3.9e-57: 200: 25.42
+	Sp
		314595 UBC2_SCHPO (1-150): 6.47e-71: 212: 77.33		UBA1_SCHPO (43-358): 2.12e-57: 205: 15.17
+	Hs
		647684 UB2D4_HUMAN (4-150): 4.74e-82: 240: 38.78		UBA1_HUMAN (17-377): 2.18e-43: 164: 14.36
+	Hs
		647506 UB2D1_HUMAN (4-150): 3.09e-81: 238: 37.42		UBA1_HUMAN (17-377): 2.18e-43: 164: 14.36
+	Hs
		647533 UB2D2_HUMAN (4-150): 2.35e-81: 238: 38.10		UBA1_HUMAN (17-377): 2.18e-43: 164: 14.36
+	Hs
		647521 UB2D3_HUMAN (4-150): 6.02e-80: 235: 38.10		UBA1_HUMAN (17-377): 2.18e-43: 164: 14.36
+	Sc
		585681 UBC4_YEAST (1-149): 7.5e-80: 235: 38.26		UBA1_YEAST (33-418): 9.82e-41: 157: 15.29
+	Sc
		438521 UBC2_YEAST (1-150): 6.19e-79: 233: 100.00		UBA1_YEAST (33-418): 9.82e-41: 157: 15.29
+	Hs
		647619 UB2E3_HUMAN (3-150): 3.05e-74: 223: 33.11		UBA1_HUMAN (17-377): 2.18e-43: 164: 14.36
+	Hs
		647626 UB2E2_HUMAN (3-150): 2.35e-74: 223: 33.11		UBA1_HUMAN (17-377): 2.18e-43: 164: 14.36
+	Hs
		647502 UBE2A_HUMAN (1-149): 6.59e-74: 220: 69.80		UBA1_HUMAN (17-377): 2.18e-43: 164: 14.36
+	Hs
		647508 UB2E1_HUMAN (3-150): 2.39e-73: 220: 33.78		UBA1_HUMAN (17-377): 2.18e-43: 164: 14.36
+	Hs
		647537 UBE2B_HUMAN (1-151): 4.68e-73: 218: 69.54		UBA1_HUMAN (17-377): 2.18e-43: 164: 14.36
+	Hs
		833587 UB2E1_HUMAN (3-150): 2.39e-73: 220: 33.78		UBA7_HUMAN (41-357): 6.74e-19: 91.7: 17.98
+	Hs
		647520 UB2G2_HUMAN (1-148): 8.79e-34: 119: 37.65		UBA1_HUMAN (17-377): 2.18e-43: 164: 14.36
+	Sc
		649516 UBC7_YEAST (1-148): 7.29e-37: 126: 37.65		UBA1_YEAST (33-418): 9.82e-41: 157: 15.29