HitPredict

Interactor 1: UBA6 (A0AVT1)
Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (EC 6.2.1.45) (Monocyte protein 4) (MOP-4) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2)
Gene: UBA6

Interactor 2: UBE2T (Q9NPD8)
Ubiquitin-conjugating enzyme E2 T (EC 2.3.2.23) (Cell proliferation-inducing gene 50 protein) (E2 ubiquitin-conjugating enzyme T) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T)
Gene: UBE2T

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	17597759
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	E1_UFD~UQ_con, ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006974 - DNA damage response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1052 Hs			1 197
+	Hs
		48347 UBA6_HUMAN (1-1052): 0: 1156: 100.00		UB2D1_HUMAN (2-152): 4.33e-77: 229: 41.72
+	Hs
		48351 UBA6_HUMAN (1-1052): 0: 1156: 100.00		UB2D2_HUMAN (2-152): 5.63e-77: 229: 41.72
+	Hs
		48349 UBA6_HUMAN (1-1052): 0: 1156: 100.00		UB2D3_HUMAN (2-152): 1.08e-75: 225: 41.06
+	Hs
		647684 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D4_HUMAN (2-152): 4.35e-78: 231: 39.74
+	Hs
		647506 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D1_HUMAN (2-152): 4.33e-77: 229: 41.72
+	Hs
		647533 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D2_HUMAN (2-152): 5.63e-77: 229: 41.72
+	Hs
		647663 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UBE2T_HUMAN (1-197): 4.74e-76: 228: 100.00
+	Hs
		647521 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D3_HUMAN (2-152): 1.08e-75: 225: 41.06
+	Hs
		647524 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UBE2N_HUMAN (4-152): 1.42e-70: 212: 44.97
+	Hs
		647619 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2E3_HUMAN (3-152): 2.35e-68: 209: 40.00
+	Hs
		647626 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2E2_HUMAN (3-152): 1.17e-68: 209: 40.00
+	Hs
		647508 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2E1_HUMAN (3-152): 2.32e-67: 206: 40.00
+	Hs
		647502 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UBE2A_HUMAN (3-149): 1.32e-66: 202: 34.01
+	Hs
		647537 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UBE2B_HUMAN (3-149): 8.57e-66: 200: 34.69
+	Sp
		314596 UBA1_SCHPO (26-1043): 0: 995: 40.25		UBC4_SCHPO (2-151): 7.97e-76: 225: 42.00
+	Sc
		585681 UBA1_YEAST (24-1046): 0: 979: 40.52		UBC4_YEAST (1-151): 1.88e-76: 227: 41.72
+	Dm
		762720 Q8T0L3_DROME (21-1045): 0: 990: 40.89		UBE2N_DROME (2-151): 5.25e-71: 213: 46.67
+	Sc
		649511 UBA1_YEAST (24-1046): 0: 979: 40.52		UBC13_YEAST (2-156): 5.08e-69: 208: 43.87
+	Sp
		150903 UBA1_SCHPO (26-1043): 0: 995: 40.25		UBC13_SCHPO (1-151): 1.2e-38: 131: 45.70
+	Hs
		833587 UBA7_HUMAN (34-1045): 0: 905: 36.34		UB2E1_HUMAN (3-152): 2.32e-67: 206: 40.00