Interactor 1: GHR (P10912)
Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]
Gene: GHR
Interactor 2: PTPRH (Q9HD43)
Receptor-type tyrosine-protein phosphatase H (R-PTP-H) (EC 3.1.3.48) (Stomach cancer-associated protein tyrosine phosphatase 1) (SAP-1) (Transmembrane-type protein-tyrosine phosphatase type H)
Gene: PTPRH
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.757 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12907755 |
| Identification Methods | array technology, phosphatase assay, far western blotting |
| Interaction Type | direct interaction, dephosphorylation reaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EpoR_lig-bind~fn3, fn3~fn3, Y_phosphatase~fn3 |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
