HitPredict

Interactor 1: AT2B4 (P23634)
Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4)
Gene: ATP2B4

Interactor 2: PTEN (P60484)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
Gene: PTEN

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34591642
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030165 - PDZ domain binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1241 Hs			1 403
+	Mm
		103522 AT2B1_MOUSE (1-1241): 0: 1156: 72.54		PTEN_MOUSE (1-403): 8.54e-168: 477: 99.75
+	Hs
		588567 AT2B1_HUMAN (1-1241): 0: 1148: 72.46		TPTE_HUMAN (1-347): 1.17e-102: 316: 33.61
+	Mm
		139289 AT2A2_MOUSE (45-1066): 0: 828: 27.01		PTEN_MOUSE (1-403): 8.54e-168: 477: 99.75
+	Hs
		561539 AT2A2_HUMAN (45-1066): 0: 733: 25.98		TPTE_HUMAN (1-347): 1.17e-102: 316: 33.61