HitPredict

Interactor 1: UBA1 (P22314)
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)
Gene: UBA1

Interactor 2: UE2NL (Q5JXB2)
Putative ubiquitin-conjugating enzyme E2 N-like (Epididymis tissue protein Li 174)
Gene: UBE2NL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37558718
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	E1_UFD~UQ_con, ThiF~UQ_con
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1058 Hs			1 153
+	Hs
		647684 UBA1_HUMAN (1-1058): 0: 1358: 100.00		UB2D4_HUMAN (4-150): 6.3e-80: 234: 41.50
+	Hs
		647506 UBA1_HUMAN (1-1058): 0: 1358: 100.00		UB2D1_HUMAN (4-150): 1.79e-79: 233: 40.82
+	Hs
		647533 UBA1_HUMAN (1-1058): 0: 1358: 100.00		UB2D2_HUMAN (4-150): 4.9e-79: 232: 42.18
+	Hs
		647521 UBA1_HUMAN (1-1058): 0: 1358: 100.00		UB2D3_HUMAN (4-150): 1.04e-77: 228: 41.50
+	Hs
		647626 UBA1_HUMAN (1-1058): 0: 1358: 100.00		UB2E2_HUMAN (1-149): 1.32e-74: 223: 41.61
+	Hs
		647619 UBA1_HUMAN (1-1058): 0: 1358: 100.00		UB2E3_HUMAN (1-149): 3.24e-74: 222: 41.61
+	Hs
		647508 UBA1_HUMAN (1-1058): 0: 1358: 100.00		UB2E1_HUMAN (1-149): 1.45e-72: 217: 42.28
+	Hs
		647524 UBA1_HUMAN (1-1058): 0: 1358: 100.00		UBE2N_HUMAN (1-153): 7.22e-71: 211: 91.50
+	Hs
		647502 UBA1_HUMAN (1-1058): 0: 1358: 100.00		UBE2A_HUMAN (1-147): 3.3e-69: 207: 35.14
+	Hs
		647663 UBA1_HUMAN (1-1058): 0: 1358: 100.00		UBE2T_HUMAN (7-149): 6.91e-32: 114: 42.18
+	Dm
		762720 Q8T0L3_DROME (36-1057): 0: 1108: 59.75		UBE2N_DROME (1-151): 1.7e-70: 210: 74.17
+	Sp
		314596 UBA1_SCHPO (36-1053): 0: 1080: 53.37		UBC4_SCHPO (4-149): 3.8e-77: 227: 42.47
+	Sc
		585681 UBA1_YEAST (38-1057): 0: 1063: 51.50		UBC4_YEAST (1-150): 2.71e-78: 230: 42.00
+	Sc
		649511 UBA1_YEAST (38-1057): 0: 1063: 51.50		UBC13_YEAST (1-151): 6.61e-70: 209: 64.90
+	Hs
		48347 UBA6_HUMAN (12-1057): 0: 1037: 41.09		UB2D1_HUMAN (4-150): 1.79e-79: 233: 40.82
+	Hs
		48351 UBA6_HUMAN (12-1057): 0: 1037: 41.09		UB2D2_HUMAN (4-150): 4.9e-79: 232: 42.18
+	Hs
		48349 UBA6_HUMAN (12-1057): 0: 1037: 41.09		UB2D3_HUMAN (4-150): 1.04e-77: 228: 41.50
+	Sp
		150903 UBA1_SCHPO (36-1053): 0: 1080: 53.37		UBC13_SCHPO (4-150): 4.32e-56: 174: 63.27
+	Hs
		833587 UBA7_HUMAN (41-1057): 0: 1006: 46.00		UB2E1_HUMAN (1-149): 1.45e-72: 217: 42.28
+	Hs
		48387 UBA6_HUMAN (12-1057): 0: 1037: 41.09		UBE2T_HUMAN (7-149): 6.91e-32: 114: 42.18