HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: LCA5 (Q86VQ0)
Lebercilin (Leber congenital amaurosis 5 protein)
Gene: LCA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	26638075, unassigned1272
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 697
+	Hs
		909762 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		LCA5_HUMAN (1-697): 1.31e-79: 269: 100.00
+	Hs
		927250 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		LCA5_HUMAN (1-697): 1.31e-79: 269: 100.00
+	Hs
		909658 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MRCKA_HUMAN (33-529): 5.45e-46: 179: 15.41
+	Hs
		683425 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MRCKA_HUMAN (33-529): 5.45e-46: 179: 15.41
+	Hs
		927145 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MRCKA_HUMAN (33-529): 5.45e-46: 179: 15.41
+	Hs
		522602 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH7_HUMAN (28-623): 3.7e-17: 88.5: 9.92
+	Hs
		927643 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH2_HUMAN (31-566): 3.64e-16: 85.1: 11.81
+	Mm
		926804 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH10_MOUSE (167-635): 1.31e-15: 83.5: 9.87
+	Hs
		551660 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DESP_HUMAN (31-635): 8.92e-16: 83.9: 12.21
+	Mm
		93548 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		DESP_MOUSE (47-591): 8.24e-13: 74.3: 13.01
+	Mm
		926855 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH9_MOUSE (163-635): 1.25e-14: 80.1: 11.90
+	Hs
		909846 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RBCC1_HUMAN (123-533): 3.58e-10: 65.8: 16.55
+	Hs
		683564 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RBCC1_HUMAN (123-533): 3.58e-10: 65.8: 16.55
+	Hs
		909524 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ROCK1_HUMAN (11-508): 8.34e-10: 64.3: 10.62
+	Hs
		725130 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH10_HUMAN (231-628): 2.38e-09: 63.1: 6.48
+	Hs
		728460 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH11_HUMAN (274-635): 7.97e-09: 61.2: 11.17
+	Hs
		927164 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MRCKG_HUMAN (80-478): 2.56e-10: 66.1: 13.40
+	Hs
		927333 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		RBCC1_HUMAN (123-533): 3.58e-10: 65.8: 16.55
+	Hs
		724761 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH9_HUMAN (217-636): 2.15e-09: 63.1: 9.91
+	Hs
		728466 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH11_HUMAN (274-635): 7.97e-09: 61.2: 11.17