HitPredict

Interactor 1: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Interactor 2: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34512150, 27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 324 Hs			1 409
+	Rn
		89028 D4AEH3_RAT (1-285): 1.43e-103: 307: 96.14		RD23B_RAT (1-409): 1.14e-120: 358: 87.23
+	Hs
		849167 PSMD7_HUMAN (1-285): 5.24e-110: 324: 100.00		RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72
+	Sc
		697121 RPN8_YEAST (7-322): 1.4e-99: 298: 47.01		RAD23_YEAST (1-407): 2.12e-72: 233: 28.41
+	Hs
		849284 PSMD7_HUMAN (1-285): 5.24e-110: 324: 100.00		UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72
+	Dm
		640796 PSMD7_DROME (3-323): 3.82e-118: 345: 75.54		Q9VWD9_DROME (1-353): 1.07e-44: 164: 11.08
+	Hs
		849280 PSMD7_HUMAN (1-285): 5.24e-110: 324: 100.00		UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68
+	Hs
		124955 EIF3F_HUMAN (2-279): 1.1e-98: 297: 26.88		UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68
+	Mm
		476691 PSMD7_MOUSE (1-285): 4.25e-110: 324: 99.30		UBC_MOUSE (1-118): 1.78e-32: 131: 21.67
+	Mm
		291863 CSN6_MOUSE (8-286): 1.4e-101: 303: 24.47		UBC_MOUSE (1-118): 1.78e-32: 131: 21.67
+	At
		188941 PSD7A_ARATH (1-289): 1.39e-106: 315: 61.03		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	At
		1091969 PSD7B_ARATH (1-289): 1.06e-105: 313: 59.66		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	At
		1091853 CSN6A_ARATH (2-290): 9e-90: 272: 22.22		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	At
		137953 EIF3F_ARATH (2-281): 4.43e-81: 249: 27.40		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	Zm
		46881 A0A3L6GBJ0_MAIZE (2-273): 6.33e-49: 169: 14.98		C0PFA7_MAIZE (2-407): 1.73e-38: 147: 13.85
+	Zm
		27878 B4FLQ8_MAIZE (5-142): 2.05e-30: 118: 27.08		A0A1D6JMS0_MAIZE (2-407): 1.23e-51: 183: 15.43
+	At
		1091793 CSN5A_ARATH (7-161): 1.07e-49: 171: 19.88		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	Mm
		193512 CSN5_MOUSE (7-160): 9.31e-42: 149: 19.38		UBC_MOUSE (1-118): 1.78e-32: 131: 21.67
+	Dm
		1358677 PSDE_DROME (5-142): 5.79e-28: 112: 24.31		Q9VWD9_DROME (1-353): 1.07e-44: 164: 11.08
+	Mm
		192886 PSDE_MOUSE (5-142): 6.8e-28: 112: 24.31		UBC_MOUSE (1-118): 1.78e-32: 131: 21.67
+	At
		1092172 PSDE_ARATH (7-142): 6.48e-31: 120: 26.76		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75