Protein: SMG9
Nonsense-mediated mRNA decay factor SMG9

Gene: SMG9
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q9H0W8

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0001654 - eye development
GO:0001701 - in utero embryonic development
GO:0005829 - cytosol
GO:0007420 - brain development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1400479

SMG1
Serine/threonine-protein kinase SMG1

4

0

Small-scale

0.678

High

1146156

K1H1
Keratin, type I cuticular Ha1

3

1

High-throughput

0.675

High

1336172

SMG8
Nonsense-mediated mRNA decay factor SMG8

3

1

Small-scale

0.675

High

1090910

TRAF2
TNF receptor-associated factor 2

3

0

High-throughput

0.646

High

300492

KRT34
Keratin, type I cuticular Ha4

2

1

High-throughput

0.606

High

1430678

RBM8A
RNA-binding protein 8A

2

0

Small-scale

0.585

High

66520

RASFA
Ras association domain-containing protein 10

2

0

High-throughput

0.580

High

210345

PHF1
PHD finger protein 1

2

0

High-throughput

0.580

High

269374

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

572208

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.580

High

725456

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

0

High-throughput

0.580

High

881741

FNTB
Protein farnesyltransferase subunit beta

2

0

High-throughput

0.580

High

920598

ARFP2
Arfaptin-2

2

0

High-throughput

0.580

High

950679

KR108
Keratin-associated protein 10-8

2

0

High-throughput

0.580

High

1048996

REL
Proto-oncogene c-Rel

2

0

High-throughput

0.580

High

1151645

TRIP6
Thyroid receptor-interacting protein 6

2

0

High-throughput

0.580

High

1201892

PKHG4
Puratrophin-1

2

0

High-throughput

0.580

High

1347454

CEP76
Centrosomal protein of 76 kDa

2

0

High-throughput

0.580

High

1380927

P2R3C
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma

2

0

High-throughput

0.580

High

1397940

KAD8
Adenylate kinase 8

2

0

High-throughput

0.580

High

1404663

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.580

High

1430671

SMG9
Nonsense-mediated mRNA decay factor SMG9

1

0

Small-scale

0.530

High

1370107

RENT1
Regulator of nonsense transcripts 1

1

0

Small-scale

0.513

High

1364988

TSC1
Hamartin

1

1

High-throughput

0.481

High

1292932

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

242883

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

346310

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

696468

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

862979

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

Small-scale

0.458

High

1108139

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1149370

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1252384

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

1322789

CNTRB
Centrobin

1

0

High-throughput

0.458

High

1334901

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1420661

UNK
RING finger protein unkempt homolog

1

0

High-throughput

0.458

High

1430673

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.458

High

1430674

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1430676

RUVB1
RuvB-like 1

1

0

Small-scale

0.458

High

1255481

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

783410

TRI23
E3 ubiquitin-protein ligase TRIM23

3

0

High-throughput

0.352

High

640284

EPHA1
Ephrin type-A receptor 1

3

0

High-throughput

0.345

High

469545

SYPH
Synaptophysin

2

0

High-throughput

0.316

High

587210

ITF2
Transcription factor 4

2

0

High-throughput

0.316

High

1006302

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.316

High

1063608

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.316

High

1081478

INCA1
Protein INCA1

2

0

High-throughput

0.316

High

1178499

GSG1
Germ cell-specific gene 1 protein

2

0

High-throughput

0.316

High

1180022

CCD57
Coiled-coil domain-containing protein 57

2

0

High-throughput

0.316

High

1205983

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

0

High-throughput

0.316

High

1231794

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

2

0

High-throughput

0.316

High

1247411

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.316

High

1253307

DG2L6
Diacylglycerol O-acyltransferase 2-like protein 6

2

0

High-throughput

0.316

High

1316820

CKLF4
CKLF-like MARVEL transmembrane domain-containing protein 4

2

0

High-throughput

0.316

High

1330227

ZN655
Zinc finger protein 655

2

0

High-throughput

0.316

High

1341233

IKBD
NF-kappa-B inhibitor delta

2

0

High-throughput

0.316

High

1411922

SWET1
Sugar transporter SWEET1

2

0

High-throughput

0.316

High

1419157

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

2

0

High-throughput

0.316

High

1429730

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

1430675

PNMA3
Paraneoplastic antigen Ma3

2

0

High-throughput

0.316

High

1310644

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

0

High-throughput

0.305

High

74597

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.279

Low

1127984

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

1

0

High-throughput

0.279

Low

1387822

ATG4C
Cysteine protease ATG4C

1

0

High-throughput

0.279

Low

1390477

DDX11
ATP-dependent DNA helicase DDX11

1

0

High-throughput

0.279

Low

1430677

DCAF1
DDB1- and CUL4-associated factor 1

1

0

High-throughput

0.279

Low

589653

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

769140

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1329863

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.249

Low

1336213

RN214
RING finger protein 214

1

0

High-throughput

0.249

Low

1430672

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

262302

SCN2B
Sodium channel regulatory subunit beta-2

1

0

High-throughput

0.232

Low

683336

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.232

Low

754095

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.232

Low

774611

BASI
Basigin

1

0

High-throughput

0.232

Low

1208279

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025