Protein: MPP10
U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10)

Gene: MPP10, MPHOSPH10
Organism: Homo sapiens
Interactions: 152
UniProt ID: O00566

Gene Ontology (top 5):
GO:0000375 - RNA splicing, via transesterification reactions
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

140638

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

3

5

Small-scale

0.873

High

140620

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

2

2

Small-scale

0.812

High

140552

RS9
Small ribosomal subunit protein uS4

1

5

High-throughput

0.691

High

140527

NPM
Nucleophosmin

3

2

High-throughput

0.667

High

140535

RS2
Small ribosomal subunit protein uS5

3

2

High-throughput

0.667

High

140565

RS6
Small ribosomal subunit protein eS6

3

1

High-throughput

0.656

High

140602

ZCCHV
Zinc finger CCCH-type antiviral protein 1

2

3

High-throughput

0.628

High

140560

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

3

0

Small-scale

0.628

High

140567

RL31
Large ribosomal subunit protein eL31

2

1

High-throughput

0.611

High

140593

IF16
Gamma-interferon-inducible protein 16

2

2

High-throughput

0.611

High

140597

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

2

1

High-throughput

0.611

High

140630

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

2

3

High-throughput

0.611

High

140558

RL37A
Large ribosomal subunit protein eL43

2

0

High-throughput

0.602

High

140611

DGCR8
Microprocessor complex subunit DGCR8

2

0

High-throughput

0.602

High

140584

KRR1
KRR1 small subunit processome component homolog

2

1

High-throughput

0.601

High

140625

RBM4B
RNA-binding protein 4B

2

0

High-throughput

0.585

High

140519

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

5

High-throughput

0.584

High

140520

MYC
Myc proto-oncogene protein

2

2

High-throughput

0.584

High

140541

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

1

High-throughput

0.584

High

140522

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

140634

ANLN
Anillin

2

0

High-throughput

0.559

High

140514

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

5

High-throughput

0.536

High

140515

NPM3
Nucleoplasmin-3

1

2

High-throughput

0.536

High

140516

RL1D1
Ribosomal L1 domain-containing protein 1

1

3

High-throughput

0.536

High

140518

PTBP3
Polypyrimidine tract-binding protein 3

1

1

High-throughput

0.536

High

140526

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.536

High

140529

RSSA
Small ribosomal subunit protein uS2

1

2

High-throughput

0.536

High

140532

H14
Histone H1.4

1

4

High-throughput

0.536

High

140536

H15
Histone H1.5

1

4

High-throughput

0.536

High

140537

H12
Histone H1.2

1

4

High-throughput

0.536

High

140540

RL17
Large ribosomal subunit protein uL22

1

1

High-throughput

0.536

High

140543

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.536

High

140545

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.536

High

140549

RL13A
Large ribosomal subunit protein uL13

1

1

High-throughput

0.536

High

140553

RS10
Small ribosomal subunit protein eS10

1

1

High-throughput

0.536

High

140561

RS8
Small ribosomal subunit protein eS8

1

2

High-throughput

0.536

High

140563

RL7A
Large ribosomal subunit protein eL8

1

2

High-throughput

0.536

High

140574

RED1
Double-stranded RNA-specific editase 1

1

3

High-throughput

0.536

High

140578

H11
Histone H1.1

1

4

High-throughput

0.536

High

140581

SRSF1
Serine/arginine-rich splicing factor 1

1

1

High-throughput

0.536

High

140582

ILF3
Interleukin enhancer-binding factor 3

1

3

High-throughput

0.536

High

140583

SRSF6
Serine/arginine-rich splicing factor 6

1

2

High-throughput

0.536

High

140588

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

1

High-throughput

0.536

High

140590

RRS1
Ribosome biogenesis regulatory protein homolog

1

1

High-throughput

0.536

High

140633

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.536

High

140635

SAS10
Something about silencing protein 10

1

3

High-throughput

0.536

High

140640

LYAR
Cell growth-regulating nucleolar protein

1

1

High-throughput

0.536

High

140652

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

140653

YBOX2
Y-box-binding protein 2

1

1

High-throughput

0.536

High

140657

RBM19
Probable RNA-binding protein 19

1

1

High-throughput

0.536

High

140572

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.527

High

140585

BYST
Bystin

1

2

High-throughput

0.515

High

140643

MO4L1
Mortality factor 4-like protein 1

1

1

High-throughput

0.515

High

140544

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.513

High

140546

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

140547

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.513

High

140550

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.513

High

140551

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

140555

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.513

High

140562

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

140564

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

140568

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

140569

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

140575

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

140579

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.513

High

140619

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

140622

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.513

High

140631

REXO4
RNA exonuclease 4

1

0

High-throughput

0.513

High

140650

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

140655

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

140525

H2A1B
Histone H2A type 1-B/E

1

2

High-throughput

0.489

High

140533

FGF3
Fibroblast growth factor 3

1

2

High-throughput

0.489

High

140542

H1T
Histone H1t

1

4

High-throughput

0.489

High

140556

FGF8
Fibroblast growth factor 8

1

2

High-throughput

0.489

High

140559

RHOA
Transforming protein RhoA

1

9

High-throughput

0.489

High

140614

FGF13
Fibroblast growth factor 13

1

2

High-throughput

0.489

High

128606

MEN1
Menin

1

1

High-throughput

0.479

High

140509

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

140511

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

140512

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

140523

GCR
Glucocorticoid receptor

1

6

High-throughput

0.479

High

140524

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.479

High

140530

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

140534

ENPL
Endoplasmin

1

2

High-throughput

0.479

High

140548

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

140554

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

140557

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

140573

NOP14
Nucleolar protein 14

1

1

High-throughput

0.479

High

140576

EXOSX
Exosome complex component 10

1

3

High-throughput

0.479

High

140589

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.479

High

140598

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.479

High

140606

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

140607

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

140608

NUP43
Nucleoporin Nup43

1

6

High-throughput

0.479

High

140609

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

140612

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

140613

KAT6A
Histone acetyltransferase KAT6A

1

3

High-throughput

0.479

High

140616

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

4

High-throughput

0.479

High

140618

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

5

High-throughput

0.479

High

140624

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

140628

DDX23
Probable ATP-dependent RNA helicase DDX23

1

1

High-throughput

0.479

High

140632

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.479

High

140637

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

4

High-throughput

0.479

High

140639

NLE1
Notchless protein homolog 1

1

4

High-throughput

0.479

High

140641

AATF
Protein AATF

1

2

High-throughput

0.479

High

140646

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

140654

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

1

Small-scale

0.479

High

140528

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

140539

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

140566

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

140570

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

140571

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

140577

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

140592

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

140596

RC3H1
Roquin-1

1

0

High-throughput

0.458

High

140603

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

140604

DHX40
Probable ATP-dependent RNA helicase DHX40

1

0

High-throughput

0.458

High

140610

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

140617

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

140629

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

140636

DDX21
Nucleolar RNA helicase 2

1

0

High-throughput

0.458

High

140642

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

140644

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.458

High

140656

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

140587

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

1

High-throughput

0.445

High

140594

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

1

High-throughput

0.445

High

131568

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

High-throughput

0.437

High

140517

RHBT1
Rho-related BTB domain-containing protein 1

1

8

High-throughput

0.437

High

140531

H2AB2
Histone H2A-Bbd type 2/3

1

3

High-throughput

0.437

High

140580

CALD1
Caldesmon

1

2

High-throughput

0.437

High

140600

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

140651

HECD1
E3 ubiquitin-protein ligase HECTD1

1

3

High-throughput

0.437

High

140538

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.426

High

140599

PSRC1
Proline/serine-rich coiled-coil protein 1

1

0

High-throughput

0.426

High

140626

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.426

High

140649

DDX41
Probable ATP-dependent RNA helicase DDX41

1

0

High-throughput

0.426

High

47469

RPSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.407

High

140627

ZNF2
Zinc finger protein 2

2

0

High-throughput

0.328

High

140513

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.279

Low

140586

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

140601

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.279

Low

140605

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.279

Low

140621

ZN668
Zinc finger protein 668

1

0

High-throughput

0.279

Low

140623

ZNF48
Zinc finger protein 48

1

0

High-throughput

0.279

Low

140645

ZBT47
Zinc finger and BTB domain-containing protein 47

1

0

High-throughput

0.279

Low

140647

IL17B
Interleukin-17B

1

0

High-throughput

0.279

Low

140648

CTNA3
Catenin alpha-3

1

0

High-throughput

0.268

Low

140510

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

140521

RASK
GTPase KRas

1

0

High-throughput

0.249

Low

140591

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

140595

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.249

Low

140615

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025