Protein: NFYC
Nuclear transcription factor Y subunit gamma (CAAT box DNA-binding protein subunit C) (Nuclear transcription factor Y subunit C) (NF-YC) (Transactivator HSM-1/2)

Gene: NFYC
Organism: Homo sapiens
Interactions: 142
UniProt ID: Q13952

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

627431

NFYB
Nuclear transcription factor Y subunit beta

9

20

Small-scale

0.977

High

966142

NC2B
Protein Dr1

3

20

High-throughput

0.861

High

617751

NFYA
Nuclear transcription factor Y subunit alpha

9

20

Small-scale

0.756

High

836219

TAF6
Transcription initiation factor TFIID subunit 6

2

0

Small-scale

0.728

High

903715

LMO4
LIM domain transcription factor LMO4

3

3

High-throughput

0.667

High

1016060

SRBP2
Sterol regulatory element-binding protein 2

3

2

High-throughput

0.667

High

1047503

POGZ
Pogo transposable element with ZNF domain

4

0

High-throughput

0.664

High

1047534

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.656

High

968967

SP2
Transcription factor Sp2

3

8

High-throughput

0.653

High

346746

MYC
Myc proto-oncogene protein

2

3

Small-scale

0.631

High

587572

NFKB1
Nuclear factor NF-kappa-B p105 subunit

2

2

High-throughput

0.628

High

1047499

LIN54
Protein lin-54 homolog

3

0

High-throughput

0.625

High

579339

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

2

1

Small-scale

0.619

High

165675

SET1A
Histone-lysine N-methyltransferase SETD1A

1

2

High-throughput

0.618

High

975248

KMT2A
Histone-lysine N-methyltransferase 2A

1

3

High-throughput

0.618

High

1047528

EP400
E1A-binding protein p400

1

4

High-throughput

0.618

High

1047494

ARID2
AT-rich interactive domain-containing protein 2

2

2

High-throughput

0.614

High

1047532

CIC
Protein capicua homolog

2

3

High-throughput

0.614

High

1047545

BICRA
BRD4-interacting chromatin-remodeling complex-associated protein

2

2

High-throughput

0.614

High

157902

KLF11
Krueppel-like factor 11

2

5

High-throughput

0.606

High

197707

CRX
Cone-rod homeobox protein

2

5

High-throughput

0.606

High

641402

PAX6
Paired box protein Pax-6

2

6

High-throughput

0.606

High

692134

ELF1
ETS-related transcription factor Elf-1

2

1

High-throughput

0.606

High

944023

PO6F2
POU domain, class 6, transcription factor 2

2

3

High-throughput

0.606

High

970882

SP4
Transcription factor Sp4

2

9

High-throughput

0.606

High

971656

PAX5
Paired box protein Pax-5

2

7

High-throughput

0.606

High

1047480

PO6F1
POU domain, class 6, transcription factor 1

2

3

High-throughput

0.606

High

1047515

ZSCA1
Zinc finger and SCAN domain-containing protein 1

2

1

High-throughput

0.606

High

1047529

HSFY1
Heat shock transcription factor, Y-linked

2

1

High-throughput

0.606

High

1047550

KLF15
Krueppel-like factor 15

2

9

High-throughput

0.606

High

1047479

NUCG
Endonuclease G, mitochondrial

2

0

High-throughput

0.602

High

1047514

COMD1
COMM domain-containing protein 1

2

0

High-throughput

0.602

High

550387

ZEP1
Zinc finger protein 40

2

1

High-throughput

0.586

High

1047485

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

0

High-throughput

0.586

High

1047506

PB1
Protein polybromo-1

1

0

High-throughput

0.586

High

953073

PR20A
Proline-rich protein 20A

3

2

High-throughput

0.586

High

299374

UBXN7
UBX domain-containing protein 7

2

0

High-throughput

0.580

High

321995

ZMYM6
Zinc finger MYM-type protein 6

2

0

High-throughput

0.580

High

795500

RAD52
DNA repair protein RAD52 homolog

2

0

High-throughput

0.580

High

1047501

STOX1
Storkhead-box protein 1

2

0

High-throughput

0.580

High

1047513

CIART
Circadian-associated transcriptional repressor

2

0

High-throughput

0.580

High

1047549

SAE1
SUMO-activating enzyme subunit 1

2

0

High-throughput

0.580

High

646485

PON1
Serum paraoxonase/arylesterase 1

2

1

High-throughput

0.574

High

1047481

PON3
Serum paraoxonase/lactonase 3

2

1

High-throughput

0.574

High

175876

P73
Tumor protein p73

2

0

Small-scale

0.559

High

159995

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

3

High-throughput

0.553

High

435089

SP1
Transcription factor Sp1

1

9

High-throughput

0.541

High

1047497

BICRL
BRD4-interacting chromatin-remodeling complex-associated protein-like

1

1

High-throughput

0.541

High

1047498

ADNP2
Activity-dependent neuroprotector homeobox protein 2

1

1

High-throughput

0.541

High

515589

SRF
Serum response factor

1

1

High-throughput

0.536

High

964179

FOXK2
Forkhead box protein K2

1

9

High-throughput

0.536

High

1047478

FHL2
Four and a half LIM domains protein 2

1

1

High-throughput

0.536

High

1047546

FOXJ2
Forkhead box protein J2

1

7

High-throughput

0.536

High

974069

DYST
Dystonin

1

0

High-throughput

0.518

High

1047490

Q3KNR5
PAX4 protein

1

6

High-throughput

0.515

High

323745

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

1047551

NXT1
NTF2-related export protein 1

1

0

High-throughput

0.513

High

381973

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

High-throughput

0.508

High

952970

PR20E
Proline-rich protein 20E

2

2

High-throughput

0.504

High

589858

TBP
TATA-box-binding protein

1

2

Small-scale

0.501

High

590573

PO3F2
POU domain, class 3, transcription factor 2

1

5

Small-scale

0.501

High

1047483

TAF11
Transcription initiation factor TFIID subunit 11

1

2

Small-scale

0.501

High

1047486

TAF12
Transcription initiation factor TFIID subunit 12

1

2

Small-scale

0.501

High

1047535

ATF6B
Cyclic AMP-dependent transcription factor ATF-6 beta

1

1

Small-scale

0.501

High

1047505

MILR1
Allergin-1

1

2

High-throughput

0.489

High

201118

PAX4
Paired box protein Pax-4

1

7

High-throughput

0.481

High

981242

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.479

High

124208

TAF4
Transcription initiation factor TFIID subunit 4

1

1

High-throughput

0.479

High

525313

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

4

High-throughput

0.479

High

569708

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

571809

XBP1
X-box-binding protein 1

1

4

Small-scale

0.479

High

625421

CDK2
Cyclin-dependent kinase 2

1

7

Small-scale

0.479

High

659657

MZF1
Myeloid zinc finger 1

1

1

Small-scale

0.479

High

817563

RFX5
DNA-binding protein RFX5

1

2

High-throughput

0.479

High

855909

ZN131
Zinc finger protein 131

1

2

High-throughput

0.479

High

856016

ZN143
Zinc finger protein 143

1

1

High-throughput

0.479

High

950177

SMAD3
Mothers against decapentaplegic homolog 3

1

2

Small-scale

0.479

High

1035232

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

3

High-throughput

0.479

High

1047482

TAF5
Transcription initiation factor TFIID subunit 5

1

1

High-throughput

0.479

High

1047484

SMAD2
Mothers against decapentaplegic homolog 2

1

2

Small-scale

0.479

High

1047488

RFX7
DNA-binding protein RFX7

1

3

High-throughput

0.479

High

1047491

GON4L
GON-4-like protein

1

1

High-throughput

0.479

High

1047492

ARI4B
AT-rich interactive domain-containing protein 4B

1

3

High-throughput

0.479

High

1047504

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

2

High-throughput

0.479

High

1047523

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1047524

KAT2B
Histone acetyltransferase KAT2B

1

5

Small-scale

0.479

High

1047539

YYAP1
YY1-associated protein 1

1

1

High-throughput

0.479

High

1047547

CXXC1
CXXC-type zinc finger protein 1

1

1

High-throughput

0.479

High

1047548

KANL3
KAT8 regulatory NSL complex subunit 3

1

1

High-throughput

0.479

High

1047509

DDX60
Probable ATP-dependent RNA helicase DDX60

1

1

High-throughput

0.470

High

81895

B7ZLH0
FAM22F protein

1

1

High-throughput

0.470

High

953010

PR20D
Proline-rich protein 20D

1

2

High-throughput

0.470

High

240389

SNX2
Sorting nexin-2

1

0

High-throughput

0.460

High

1047511

ZNF34
Zinc finger protein 34

1

0

High-throughput

0.460

High

124329

RFXAP
Regulatory factor X-associated protein

1

0

High-throughput

0.458

High

149858

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.458

High

233437

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

529093

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

Small-scale

0.458

High

536822

TRI27
Zinc finger protein RFP

1

0

Small-scale

0.458

High

972506

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

0

High-throughput

0.458

High

1016762

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.458

High

1038363

HDAC1
Histone deacetylase 1

1

0

Small-scale

0.458

High

1047487

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.458

High

1047493

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.458

High

1047500

NFRKB
Nuclear factor related to kappa-B-binding protein

1

0

High-throughput

0.458

High

1047502

ASXL2
Putative Polycomb group protein ASXL2

1

0

High-throughput

0.458

High

1047508

MGAP
MAX gene-associated protein

1

0

High-throughput

0.458

High

1047519

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1047521

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1047526

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

High-throughput

0.458

High

1047531

PHF12
PHD finger protein 12

1

0

High-throughput

0.458

High

1047540

KANL2
KAT8 regulatory NSL complex subunit 2

1

0

High-throughput

0.458

High

1047542

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

1047543

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.458

High

50823

NTM2F
NUT family member 2F

1

1

High-throughput

0.439

High

1047495

USF3
Basic helix-loop-helix domain-containing protein USF3

1

0

High-throughput

0.438

High

519382

FCG2A
Low affinity immunoglobulin gamma Fc region receptor II-a

1

1

High-throughput

0.437

High

1047518

ALMS1
Centrosome-associated protein ALMS1

1

1

High-throughput

0.437

High

1047541

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

1047510

SMAP1
Stromal membrane-associated protein 1

2

0

High-throughput

0.316

High

1047512

AGRF5
Adhesion G protein-coupled receptor F5

2

0

High-throughput

0.316

High

1047516

CEP76
Centrosomal protein of 76 kDa

2

0

High-throughput

0.316

High

1047517

CX038
Uncharacterized protein CXorf38

2

0

High-throughput

0.316

High

1047522

F168A
Protein FAM168A

2

0

High-throughput

0.316

High

1047527

KLD7B
Kelch domain-containing protein 7B

2

0

High-throughput

0.316

High

1047538

DHRS6
Dehydrogenase/reductase SDR family member 6

2

0

High-throughput

0.316

High

409375

CASB
Beta-casein

1

0

High-throughput

0.282

High

1047507

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

1047489

CR1L
Complement component receptor 1-like protein

1

0

High-throughput

0.279

Low

1047496

K1C40
Keratin, type I cytoskeletal 40

1

0

High-throughput

0.279

Low

1047530

TGM7
Protein-glutamine gamma-glutamyltransferase Z

1

0

High-throughput

0.279

Low

1047552

KIF3A
Kinesin-like protein KIF3A

1

0

High-throughput

0.279

Low

1047537

Q9BRG6
APOL4 protein

1

0

High-throughput

0.268

Low

1047520

TITIN
Titin

1

0

High-throughput

0.261

Low

1047525

OSTF1
Osteoclast-stimulating factor 1

1

0

High-throughput

0.251

Low

1047536

APOL4
Apolipoprotein L4

1

0

High-throughput

0.251

Low

517910

COBA1

1

0

Small-scale

0.249

Low

603164

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

0

High-throughput

0.249

Low

813448

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.249

Low

964713

FCERB
High affinity immunoglobulin epsilon receptor subunit beta

1

0

Small-scale

0.249

Low

1047533

METH
Methionine synthase

1

0

High-throughput

0.249

Low

1047544

ASND1
Asparagine synthetase domain-containing protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024