Protein: PR38A
Pre-mRNA-splicing factor 38A

Gene: PR38A, PRPF38A
Organism: Homo sapiens
Interactions: 162
UniProt ID: Q8NAV1

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0071005 - U2-type precatalytic spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

935567

MFAP1
Microfibrillar-associated protein 1

5

3

High-throughput

0.916

High

1006559

SRPK2
SRSF protein kinase 2

8

4

High-throughput

0.755

High

1332845

SDCB2
Syntenin-2

4

1

High-throughput

0.698

High

1332837

SRPK1
SRSF protein kinase 1

3

4

High-throughput

0.677

High

1239629

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

4

0

Small-scale

0.675

High

938240

SEC13
Protein SEC13 homolog

3

0

High-throughput

0.638

High

889614

CLK2
Dual specificity protein kinase CLK2

2

1

High-throughput

0.633

High

1016519

SRSF3
Serine/arginine-rich splicing factor 3

2

4

High-throughput

0.625

High

1332818

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.622

High

508283

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.614

High

1160003

SRSF7
Serine/arginine-rich splicing factor 7

2

2

High-throughput

0.606

High

889460

CLK1
Dual specificity protein kinase CLK1

2

1

High-throughput

0.594

High

1332835

ZMAT2
Zinc finger matrin-type protein 2

1

0

High-throughput

0.586

High

1127012

RBM39
RNA-binding protein 39

2

0

High-throughput

0.575

High

140364

SDCB1
Syntenin-1

1

1

High-throughput

0.573

High

396524

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

372593

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

904937

MECP2
Methyl-CpG-binding protein 2

2

0

High-throughput

0.559

High

997866

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.550

High

1242418

RHGBA
Rho GTPase-activating protein 11A

2

0

High-throughput

0.547

High

1332842

UBL5
Ubiquitin-like protein 5

1

0

Small-scale

0.546

High

74550

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

1

High-throughput

0.536

High

256647

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

1

High-throughput

0.536

High

277378

TP4A3
Protein tyrosine phosphatase type IVA 3

1

1

High-throughput

0.536

High

659258

SP100
Nuclear autoantigen Sp-100

1

1

High-throughput

0.536

High

788103

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

1099164

SRSF5
Serine/arginine-rich splicing factor 5

1

3

High-throughput

0.536

High

1099439

SRSF6
Serine/arginine-rich splicing factor 6

1

3

High-throughput

0.536

High

1146294

E2F5
Transcription factor E2F5

1

1

High-throughput

0.536

High

1332862

SRPK3
SRSF protein kinase 3

1

5

High-throughput

0.536

High

1085782

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.518

High

1122752

DPOA2
DNA polymerase alpha subunit B

1

0

High-throughput

0.518

High

158659

TYB4Y
Thymosin beta-4, Y-chromosomal

1

0

High-throughput

0.513

High

471136

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

480229

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

659920

H2B1O
Histone H2B type 1-O

1

0

High-throughput

0.513

High

948557

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

973238

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.513

High

983889

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.513

High

991369

SUMO1
Small ubiquitin-related modifier 1

1

0

High-throughput

0.513

High

1023576

CYC
Cytochrome c

1

0

High-throughput

0.513

High

1088915

TP53B
TP53-binding protein 1

1

0

High-throughput

0.513

High

1142800

PEA15
Astrocytic phosphoprotein PEA-15

1

0

High-throughput

0.513

High

1154276

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

0

High-throughput

0.513

High

1332829

EZH1
Histone-lysine N-methyltransferase EZH1

1

0

High-throughput

0.513

High

1332840

H2AJ
Histone H2A.J

1

0

High-throughput

0.513

High

1332852

KTU
Protein kintoun

1

0

High-throughput

0.513

High

1332861

TPX2
Targeting protein for Xklp2

1

0

High-throughput

0.513

High

1332865

CFA20
Cilia- and flagella-associated protein 20

1

0

High-throughput

0.513

High

1062049

SRSF4
Serine/arginine-rich splicing factor 4

1

2

High-throughput

0.508

High

162632

ANM5
Protein arginine N-methyltransferase 5

1

0

High-throughput

0.486

High

1028679

U2AF1
Splicing factor U2AF 35 kDa subunit

1

0

High-throughput

0.486

High

1104972

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

0

High-throughput

0.486

High

1128060

DHX8
ATP-dependent RNA helicase DHX8

1

0

High-throughput

0.486

High

1145278

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.486

High

1161154

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.486

High

1311247

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

0

High-throughput

0.486

High

254390

CC14B
Dual specificity protein phosphatase CDC14B

1

1

High-throughput

0.479

High

280731

PR40A
Pre-mRNA-processing factor 40 homolog A

1

1

High-throughput

0.479

High

318513

TOX4
TOX high mobility group box family member 4

1

1

High-throughput

0.479

High

331150

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

472896

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

871979

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

1

High-throughput

0.479

High

1035781

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1107930

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

1109170

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

2

High-throughput

0.479

High

1156778

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

1161547

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1205072

FA76B
Protein FAM76B

1

1

High-throughput

0.479

High

1235471

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

1332821

FA76A
Protein FAM76A

1

1

High-throughput

0.479

High

1332823

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

1

High-throughput

0.479

High

1332828

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

67839

SRRM4
Serine/arginine repetitive matrix protein 4

1

0

High-throughput

0.460

High

767471

RADI
Radixin

1

0

High-throughput

0.460

High

1332838

SRSF8
Serine/arginine-rich splicing factor 8

1

0

High-throughput

0.460

High

1332863

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.460

High

96722

E9PAV9
G patch domain-containing protein 4

1

0

High-throughput

0.458

High

173085

XPO1
Exportin-1

1

0

High-throughput

0.458

High

223181

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

228319

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

248000

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

258520

KIN17
DNA/RNA-binding protein KIN17

1

0

Small-scale

0.458

High

285368

EED
Polycomb protein EED

1

0

High-throughput

0.458

High

302584

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

Small-scale

0.458

High

385980

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

401152

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

583327

FOLR1
Folate receptor alpha

1

0

High-throughput

0.458

High

589173

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

675588

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

695955

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

768658

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

807502

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.458

High

868556

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

877174

KC1D
Casein kinase I isoform delta

1

0

High-throughput

0.458

High

879277

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

889153

RBM25
RNA-binding protein 25

1

0

High-throughput

0.458

High

970790

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

979996

H4
Histone H4

1

0

High-throughput

0.458

High

1059603

SPAG1
Sperm-associated antigen 1

1

0

High-throughput

0.458

High

1100134

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1140569

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1241270

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.458

High

1248040

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

0

High-throughput

0.458

High

1271735

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1277857

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1290592

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1294090

DDX42
ATP-dependent RNA helicase DDX42

1

0

High-throughput

0.458

High

1327867

NOPC1
NOP protein chaperone 1

1

0

High-throughput

0.458

High

1328864

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.458

High

1329047

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

0

High-throughput

0.458

High

1332820

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1332824

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

0

High-throughput

0.458

High

1332825

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.458

High

1332832

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1332834

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.458

High

1332836

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

0

High-throughput

0.458

High

1332841

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.458

High

1332843

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1332844

NSRP1
Nuclear speckle splicing regulatory protein 1

1

0

High-throughput

0.458

High

1332846

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1332847

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1332848

ANLN
Anillin

1

0

High-throughput

0.458

High

1332849

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1332853

WDR70
WD repeat-containing protein 70

1

0

High-throughput

0.458

High

1332856

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.458

High

1332857

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1332859

CCNL1
Cyclin-L1

1

0

High-throughput

0.458

High

1332864

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.458

High

1332858

DDX41
Probable ATP-dependent RNA helicase DDX41

1

1

High-throughput

0.445

High

1295494

MIB1
E3 ubiquitin-protein ligase MIB1

1

1

High-throughput

0.437

High

1198601

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

1256702

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.328

High

1332830

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

0

High-throughput

0.316

High

1332833

AP2M1
AP-2 complex subunit mu

2

0

High-throughput

0.316

High

169194

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.279

Low

354023

CX001
Putative transmembrane protein CXorf1

1

0

High-throughput

0.279

Low

488063

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.279

Low

515889

SAA1
Serum amyloid A-1 protein

1

0

High-throughput

0.279

Low

1092790

MALL
MAL-like protein

1

0

High-throughput

0.279

Low

1196238

GAG2E
G antigen 2E

1

0

High-throughput

0.279

Low

1237872

MYORG
Myogenesis-regulating glycosidase

1

0

High-throughput

0.279

Low

1258139

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

0

High-throughput

0.279

Low

1332819

FDSCP
Follicular dendritic cell secreted peptide

1

0

High-throughput

0.279

Low

1332826

JPH3
Junctophilin-3

1

0

High-throughput

0.279

Low

1332831

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1332850

TM14B
Transmembrane protein 14B

1

0

High-throughput

0.279

Low

1332851

ACER3
Alkaline ceramidase 3

1

0

High-throughput

0.279

Low

1332854

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.279

Low

1332855

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low

1332860

ANR50
Ankyrin repeat domain-containing protein 50

1

0

High-throughput

0.279

Low

1332866

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

1332822

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.265

Low

422615

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

126151

AP3B1
AP-3 complex subunit beta-1

1

0

High-throughput

0.249

Low

157620

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

720512

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.249

Low

1124654

SRC8
Src substrate cortactin

1

0

High-throughput

0.249

Low

1254660

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1332839

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.249

Low

1332827

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025