Protein: SHOT1
Shootin-1 (Shootin1)

Gene: SHOT1, SHTN1
Organism: Homo sapiens
Interactions: 93
UniProt ID: A0MZ66

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005874 - microtubule
GO:0005875 - microtubule associated complex
GO:0006930 - substrate-dependent cell migration, cell extension
GO:0007265 - Ras protein signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

49357

NDK7
Nucleoside diphosphate kinase homolog 7

3

0

High-throughput

0.646

High

49268

SHOT1
Shootin-1

3

0

High-throughput

0.639

High

49333

LNX1
E3 ubiquitin-protein ligase LNX

2

1

Small-scale

0.629

High

49289

1433B
14-3-3 protein beta/alpha

2

6

High-throughput

0.628

High

49307

1433Z
14-3-3 protein zeta/delta

2

6

High-throughput

0.628

High

49346

RNF41
E3 ubiquitin-protein ligase NRDP1

2

2

Small-scale

0.621

High

49303

1433G
14-3-3 protein gamma

2

6

High-throughput

0.611

High

49305

1433E
14-3-3 protein epsilon

2

0

High-throughput

0.602

High

49343

NDEL1
Nuclear distribution protein nudE-like 1

2

0

High-throughput

0.602

High

49278

PCNT
Pericentrin

1

1

High-throughput

0.541

High

49358

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.537

High

49288

1433T
14-3-3 protein theta

1

6

High-throughput

0.536

High

49290

1433S
14-3-3 protein sigma

1

6

High-throughput

0.536

High

49312

1433F
14-3-3 protein eta

1

6

High-throughput

0.536

High

49274

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.518

High

49299

ANM2
Protein arginine N-methyltransferase 2

1

0

High-throughput

0.518

High

49291

AHR
Aryl hydrocarbon receptor

1

0

High-throughput

0.513

High

49334

DOK4
Docking protein 4

1

0

High-throughput

0.513

High

49355

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

1

0

High-throughput

0.513

High

49328

LNX2
Ligand of Numb protein X 2

1

1

Small-scale

0.512

High

49294

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

1

High-throughput

0.501

High

49318

ASPP2
Apoptosis-stimulating of p53 protein 2

1

2

High-throughput

0.481

High

49295

YAP1
Transcriptional coactivator YAP1

1

3

High-throughput

0.479

High

49301

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.479

High

49308

ACTC
Actin, alpha cardiac muscle 1

1

1

High-throughput

0.479

High

49323

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

49344

WWTR1
WW domain-containing transcription regulator protein 1

1

3

High-throughput

0.479

High

49345

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

49275

PRAF2
PRA1 family protein 2

1

1

High-throughput

0.470

High

49276

PRAF3
PRA1 family protein 3

1

1

High-throughput

0.470

High

49313

Q05BL1
TP53BP2 protein

1

2

High-throughput

0.470

High

49273

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

0

High-throughput

0.458

High

49279

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

49282

PROF1
Profilin-1

1

0

High-throughput

0.458

High

49284

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

49286

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

49292

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

49297

NUMB
Protein numb homolog

1

0

Small-scale

0.458

High

49302

RAC3
Ras-related C3 botulinum toxin substrate 3

1

0

High-throughput

0.458

High

49310

CENPE
Centromere-associated protein E

1

0

High-throughput

0.458

High

49315

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

High-throughput

0.458

High

49317

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

49319

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

49327

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.458

High

49336

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

49337

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

49352

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

49342

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.438

High

49350

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

49353

TNIK
TRAF2 and NCK-interacting protein kinase

1

0

High-throughput

0.438

High

49311

RON
Macrophage-stimulating protein receptor

1

1

High-throughput

0.437

High

49283

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

49298

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

49348

ZCC17
Zinc finger CCHC domain-containing protein 17

4

0

High-throughput

0.364

High

49280

FABPH
Fatty acid-binding protein, heart

3

0

High-throughput

0.352

High

49306

ERR3
Estrogen-related receptor gamma

3

0

High-throughput

0.352

High

49326

LUR1L
Leucine rich adaptor protein 1-like

3

0

High-throughput

0.347

High

49281

CHLE
Cholinesterase

2

0

High-throughput

0.328

High

49300

CAV3
Caveolin-3

2

0

High-throughput

0.328

High

49341

F167A
Protein FAM167A

2

0

High-throughput

0.328

High

49320

TNIP1
TNFAIP3-interacting protein 1

2

0

High-throughput

0.316

High

49356

EXC6B
Exocyst complex component 6B

2

0

High-throughput

0.316

High

49277

BODG
Gamma-butyrobetaine dioxygenase

1

0

High-throughput

0.299

High

49314

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.299

High

49296

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.282

High

49287

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.279

Low

49293

PRS6B
26S proteasome regulatory subunit 6B

1

0

High-throughput

0.279

Low

49309

SP2
Transcription factor Sp2

1

0

High-throughput

0.279

Low

49316

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.279

Low

49321

TEX30
Testis-expressed protein 30

1

0

High-throughput

0.279

Low

49329

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.279

Low

49330

FA24B
Protein FAM24B

1

0

High-throughput

0.279

Low

49331

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.279

Low

49332

BBS1
BBSome complex member BBS1

1

0

High-throughput

0.279

Low

49335

ANR49
Ankyrin repeat domain-containing protein 49

1

0

High-throughput

0.279

Low

49338

MRP9
ATP-binding cassette sub-family C member 12

1

0

High-throughput

0.279

Low

49347

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

0

High-throughput

0.279

Low

49322

Q6PJR7
IGL@ protein

1

0

High-throughput

0.268

Low

49270

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

49272

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.249

Low

49304

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

49324

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

49325

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

49349

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low

49351

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

49354

RCOR1
REST corepressor 1

1

0

High-throughput

0.249

Low

49285

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.238

Low

49340

MEG10
Multiple epidermal growth factor-like domains protein 10

1

0

Small-scale

0.238

Low

3694

A0A126GVR8
Olfactory receptor

1

0

High-throughput

0.232

Low

49269

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low

49271

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.232

Low

49339

S45A3
Solute carrier family 45 member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025