Protein: SARM1
NAD(+) hydrolase SARM1 (NADase SARM1) (hSARM1) (EC 3.2.2.6) (NADP(+) hydrolase SARM1) (EC 3.2.2.-) (Sterile alpha and Armadillo repeat protein) (Sterile alpha and TIR motif-containing protein 1) (Sterile alpha motif domain-containing protein 2) (MyD88-5) (SAM domain-containing protein 2) (Tir-1 homolog) (HsTIR)

Gene: SARM1
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q6SZW1

Gene Ontology (top 5):
GO:0003953 - NAD+ nucleosidase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1247696

TCAM2
TIR domain-containing adapter molecule 2

2

1

Small-scale

0.800

High

1247708

MYD88
Myeloid differentiation primary response protein MyD88

2

2

Small-scale

0.800

High

1247689

SARM1
NAD(+) hydrolase SARM1

1

9

Small-scale

0.716

High

1247710

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

1

High-throughput

0.691

High

1247712

GHITM
Growth hormone-inducible transmembrane protein

3

0

High-throughput

0.655

High

1247700

CARME
Carnosine N-methyltransferase

3

0

High-throughput

0.638

High

1247698

MIRO2
Mitochondrial Rho GTPase 2

2

5

High-throughput

0.628

High

1247702

POC1B
POC1 centriolar protein homolog B

2

5

High-throughput

0.628

High

946664

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

0

Small-scale

0.614

High

1247697

TCAM1
TIR domain-containing adapter molecule 1

2

1

Small-scale

0.606

High

466921

ACM4
Muscarinic acetylcholine receptor M4

2

0

High-throughput

0.602

High

941355

CAV3
Caveolin-3

2

0

High-throughput

0.602

High

1247706

PAUF
Pancreatic adenocarcinoma up-regulated factor

2

0

High-throughput

0.602

High

210193

IRAK2
Interleukin-1 receptor-associated kinase-like 2

1

2

High-throughput

0.578

High

1247695

NLRX1
NLR family member X1

1

1

High-throughput

0.578

High

1247720

MTCH2
Mitochondrial carrier homolog 2

2

3

High-throughput

0.571

High

1247694

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

0

High-throughput

0.546

High

193874

XLRS1
Retinoschisin

1

3

Small-scale

0.536

High

1115742

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.536

High

1247711

SEM4C
Semaphorin-4C

1

1

High-throughput

0.536

High

863490

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

1

High-throughput

0.528

High

905598

IRAK1
Interleukin-1 receptor-associated kinase 1

1

4

High-throughput

0.515

High

1247718

HYOU1
Hypoxia up-regulated protein 1

1

1

High-throughput

0.515

High

388228

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

467695

CEL2A
Chymotrypsin-like elastase family member 2A

1

0

High-throughput

0.513

High

486578

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

1247716

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.513

High

1247719

NPTN
Neuroplastin

1

0

High-throughput

0.513

High

1053805

KDSR
3-ketodihydrosphingosine reductase

1

3

High-throughput

0.489

High

412120

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

529979

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.479

High

830945

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

1090728

TRAF2
TNF receptor-associated factor 2

1

4

Small-scale

0.479

High

1247690

LMBRL
Protein LMBR1L

1

2

High-throughput

0.479

High

1247692

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

1247704

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

1247707

RING2
E3 ubiquitin-protein ligase RING2

1

5

High-throughput

0.479

High

1247709

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

Small-scale

0.479

High

1247713

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.479

High

1247714

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.479

High

1247717

TRAF6
TNF receptor-associated factor 6

1

5

Small-scale

0.479

High

1247691

NFXL1
NF-X1-type zinc finger protein NFXL1

1

1

High-throughput

0.470

High

164365

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

898486

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

1147619

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

Small-scale

0.458

High

1247693

BCAP
Phosphoinositide 3-kinase adapter protein 1

1

0

Small-scale

0.458

High

934762

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.445

High

1247715

MTCH1
Mitochondrial carrier homolog 1

1

2

High-throughput

0.445

High

588964

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

768472

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1131552

MFS10
Major facilitator superfamily domain-containing protein 10

1

1

High-throughput

0.407

High

1247699

CA087
Uncharacterized protein C1orf87

2

0

High-throughput

0.328

High

1247705

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.301

High

49526

SHSA3
Protein shisa-3 homolog

1

0

High-throughput

0.279

Low

162215

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.269

Low

170817

CLGN
Calmegin

1

0

High-throughput

0.269

Low

1242143

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.232

Low

1247701

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

0

High-throughput

0.232

Low

1247703

S39A7
Zinc transporter SLC39A7

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025