Protein: TCAM2
TIR domain-containing adapter molecule 2 (TICAM-2) (Putative NF-kappa-B-activating protein 502) (TRIF-related adapter molecule) (Toll-like receptor adaptor protein 3) (Toll/interleukin-1 receptor domain-containing protein) (MyD88-4)

Gene: TCAM2, TICAM2
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q86XR7

Gene Ontology (top 5):
GO:0001891 - phagocytic cup
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005770 - late endosome
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1247696

SARM1
NAD(+) hydrolase SARM1

2

1

Small-scale

0.800

High

126319

TLR4
Toll-like receptor 4

8

8

Small-scale

0.747

High

1294139

TCAM2
TIR domain-containing adapter molecule 2

2

3

Small-scale

0.730

High

1294140

TCAM1
TIR domain-containing adapter molecule 1

4

3

Small-scale

0.683

High

1294150

TRAF6
TNF receptor-associated factor 6

2

12

Small-scale

0.646

High

946667

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

0

Small-scale

0.631

High

1294146

MYD88
Myeloid differentiation primary response protein MyD88

1

12

Small-scale

0.618

High

410928

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

1

High-throughput

0.536

High

690103

AVR2A
Activin receptor type-2A

1

1

High-throughput

0.536

High

787198

BMR1A
Bone morphogenetic protein receptor type-1A

1

1

High-throughput

0.536

High

1035004

KPCE
Protein kinase C epsilon type

1

1

Small-scale

0.516

High

575757

IL1R1
Interleukin-1 receptor type 1

1

1

Small-scale

0.515

High

1294148

IL1AP
Interleukin-1 receptor accessory protein

1

7

Small-scale

0.515

High

549814

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

High-throughput

0.513

High

658730

JAK1
Tyrosine-protein kinase JAK1

1

0

High-throughput

0.513

High

720270

UFO
Tyrosine-protein kinase receptor UFO

1

0

High-throughput

0.513

High

1245087

RHDF2
Inactive rhomboid protein 2

1

0

High-throughput

0.513

High

1294141

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

297832

PIAS2
E3 SUMO-protein ligase PIAS2

1

1

High-throughput

0.494

High

210196

IRAK2
Interleukin-1 receptor-associated kinase-like 2

1

1

Small-scale

0.479

High

631324

RAB5A
Ras-related protein Rab-5A

1

1

High-throughput

0.479

High

1294151

IRAK3
Interleukin-1 receptor-associated kinase 3

1

1

Small-scale

0.479

High

193595

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

0

High-throughput

0.458

High

418247

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

947219

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

1294142

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

888912

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.445

High

1146569

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.445

High

1254490

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1294149

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

130153

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.426

High

698842

CALX
Calnexin

1

0

High-throughput

0.426

High

1142474

RAGE
Advanced glycosylation end product-specific receptor

1

0

Small-scale

0.426

High

1294143

YIPF5
Protein YIPF5

1

0

High-throughput

0.426

High

1294147

RAB1B
Ras-related protein Rab-1B

1

0

High-throughput

0.426

High

1294145

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

893987

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.299

High

1294144

BSCL2
Seipin

1

0

High-throughput

0.279

Low

391631

FRIH
Ferritin heavy chain

1

0

High-throughput

0.251

Low

1135491

T132D
Transmembrane protein 132D

1

0

Small-scale

0.251

Low

855466

ATRX
Transcriptional regulator ATRX

1

0

High-throughput

0.249

Low

1106597

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025