Protein: PROX1
Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1)

Gene: PROX1
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q92786

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

782609

HNF4A
Hepatocyte nuclear factor 4-alpha

2

2

Small-scale

0.615

High

130333

NR5A2
Nuclear receptor subfamily 5 group A member 2

2

5

Small-scale

0.614

High

914667

ERR3
Estrogen-related receptor gamma

2

2

High-throughput

0.614

High

881246

CTBP2
C-terminal-binding protein 2

1

2

High-throughput

0.573

High

998939

EP300
Histone acetyltransferase p300

1

2

Small-scale

0.552

High

639036

S100P
Protein S100-P

1

1

High-throughput

0.536

High

1050136

GIT2
ARF GTPase-activating protein GIT2

1

0

High-throughput

0.518

High

1071062

IRF4
Interferon regulatory factor 4

1

0

High-throughput

0.518

High

1121699

LBH
Protein LBH

1

0

High-throughput

0.518

High

1270738

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

0

High-throughput

0.518

High

177345

HDAC3
Histone deacetylase 3

1

3

Small-scale

0.515

High

595945

HNF1A
Hepatocyte nuclear factor 1-alpha

1

1

Small-scale

0.515

High

997837

RBBP4
Histone-binding protein RBBP4

1

0

High-throughput

0.513

High

1246256

MB3L2
Methyl-CpG-binding domain protein 3-like 2

1

0

High-throughput

0.513

High

1270740

CYH4
Cytohesin-4

1

0

High-throughput

0.513

High

977274

CEBPZ
CCAAT/enhancer-binding protein zeta

1

0

High-throughput

0.493

High

661375

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

437645

MCR
Mineralocorticoid receptor

1

3

High-throughput

0.481

High

510030

ERR1
Steroid hormone receptor ERR1

1

2

High-throughput

0.481

High

723189

RORA
Nuclear receptor ROR-alpha

1

4

High-throughput

0.481

High

975457

PPARD
Peroxisome proliferator-activated receptor delta

1

3

High-throughput

0.481

High

641505

PAX6
Paired box protein Pax-6

1

0

Small-scale

0.480

High

164445

TRI66
Tripartite motif-containing protein 66

1

1

High-throughput

0.479

High

244729

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

740565

PPARG
Peroxisome proliferator-activated receptor gamma

1

4

Small-scale

0.479

High

1067080

BRD3
Bromodomain-containing protein 3

1

3

High-throughput

0.479

High

1270741

BRPF3
Bromodomain and PHD finger-containing protein 3

1

1

High-throughput

0.479

High

950233

SMAD3
Mothers against decapentaplegic homolog 3

1

0

High-throughput

0.460

High

352934

IFNG
Interferon gamma

1

0

Small-scale

0.458

High

385280

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

591040

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

928156

SUMO1
Small ubiquitin-related modifier 1

1

0

Small-scale

0.458

High

1059771

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

1270737

FGF11
Fibroblast growth factor 11

1

0

High-throughput

0.458

High

1270739

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1030596

STF1
Steroidogenic factor 1

1

5

Small-scale

0.457

High

1032539

CTBP1
C-terminal-binding protein 1

1

2

High-throughput

0.445

High

1270346

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.445

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024