Protein: SPC25
Kinetochore protein Spc25 (hSpc25)

Gene: SPC25
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q9HBM1

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0007052 - mitotic spindle organization
GO:0007059 - chromosome segregation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1240512

SPC24
Kinetochore protein Spc24

9

2

Small-scale

0.974

High

155126

NDC80
Kinetochore protein NDC80 homolog

8

3

Small-scale

0.755

High

1317800

NUF2
Kinetochore protein Nuf2

6

3

High-throughput

0.736

High

1327288

MIS12
Protein MIS12 homolog

8

0

Small-scale

0.722

High

308024

ZWINT
ZW10 interactor

6

0

High-throughput

0.704

High

1330480

DSN1
Kinetochore-associated protein DSN1 homolog

5

0

High-throughput

0.691

High

1245343

KNL1
Kinetochore scaffold 1

5

0

Small-scale

0.686

High

787974

EPS15
Epidermal growth factor receptor substrate 15

3

1

High-throughput

0.667

High

1335535

EP15R
Epidermal growth factor receptor substrate 15-like 1

3

1

High-throughput

0.667

High

49693

F170A
Protein FAM170A

3

0

High-throughput

0.638

High

320419

SNP29
Synaptosomal-associated protein 29

3

0

High-throughput

0.638

High

1001596

FCHO2
F-BAR domain only protein 2

3

0

High-throughput

0.638

High

1148974

CYTSA
Cytospin-A

3

0

High-throughput

0.638

High

1158403

PMF1
Polyamine-modulated factor 1

3

0

High-throughput

0.638

High

1294761

NSL1
Kinetochore-associated protein NSL1 homolog

3

0

High-throughput

0.638

High

1233713

KIF2B
Kinesin-like protein KIF2B

2

0

High-throughput

0.602

High

1146851

A16L1
Autophagy-related protein 16-1

2

0

High-throughput

0.585

High

160197

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

0

High-throughput

0.580

High

416705

S10A6
Protein S100-A6

1

3

High-throughput

0.536

High

639089

S100P
Protein S100-P

1

3

High-throughput

0.536

High

642996

S10A4
Protein S100-A4

1

3

High-throughput

0.536

High

211067

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

1

High-throughput

0.515

High

122235

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.513

High

666973

TKT
Transketolase

1

0

High-throughput

0.513

High

714424

HSP74
Heat shock 70 kDa protein 4

1

0

High-throughput

0.513

High

790007

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.513

High

1184472

CENPQ
Centromere protein Q

1

0

High-throughput

0.513

High

1305105

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.513

High

661448

S10A2
Protein S100-A2

1

3

High-throughput

0.489

High

708367

TTK
Dual specificity protein kinase TTK

1

0

Small-scale

0.479

High

1285935

CENPT
Centromere protein T

1

1

Small-scale

0.479

High

228756

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

271791

PRDM1
PR domain zinc finger protein 1

1

0

Small-scale

0.458

High

272721

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

321644

AP2A1
AP-2 complex subunit alpha-1

1

0

High-throughput

0.458

High

890435

SC61B
Protein transport protein Sec61 subunit beta

1

0

Small-scale

0.458

High

1017353

BPTF
Nucleosome-remodeling factor subunit BPTF

1

0

High-throughput

0.458

High

1064736

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1190722

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.458

High

1218763

GCC2
GRIP and coiled-coil domain-containing protein 2

1

0

High-throughput

0.458

High

1302992

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1330156

BOLA2
BolA-like protein 2

1

0

High-throughput

0.458

High

1219017

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

1331335

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

738701

TNR3
Tumor necrosis factor receptor superfamily member 3

3

0

High-throughput

0.347

High

1093044

CSPP1
Centrosome and spindle pole-associated protein 1

2

0

High-throughput

0.328

High

1199882

KTN1
Kinectin

2

0

High-throughput

0.318

High

1268096

MY18A
Unconventional myosin-XVIIIa

2

0

High-throughput

0.318

High

1286428

CSTOS
Protein CUSTOS

2

0

High-throughput

0.318

High

856470

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1083247

CART

1

0

High-throughput

0.279

Low

1132264

CF141
Uncharacterized protein C6orf141

1

0

High-throughput

0.279

Low

1222000

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.279

Low

206007

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

825559

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.249

Low

1171788

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1332955

AAMDC
Mth938 domain-containing protein

1

0

High-throughput

0.249

Low

1333091

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.249

Low

1335534

ARMX1
Armadillo repeat-containing X-linked protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024