Protein: PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (EC 2.4.1.198) (GlcNAc-PI synthesis protein) (Phosphatidylinositol-glycan biosynthesis class A protein) (PIG-A)

Gene: PIGA
Organism: Homo sapiens
Interactions: 58
UniProt ID: P37287

Gene Ontology (top 5):
GO:0000506 - glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0005789 - endoplasmic reticulum membrane
GO:0006506 - GPI anchor biosynthetic process
GO:0008194 - UDP-glycosyltransferase activity
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

790145

PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

4

0

Small-scale

0.667

High

790153

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

4

0

Small-scale

0.660

High

790175

PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

3

0

Small-scale

0.638

High

790146

EVA1C
Protein eva-1 homolog C

3

0

High-throughput

0.638

High

790184

PCDGG
Protocadherin gamma-B4

2

2

High-throughput

0.628

High

790165

CC107
Coiled-coil domain-containing protein 107

2

0

High-throughput

0.602

High

790166

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

0

High-throughput

0.602

High

790174

KCNS3
Delayed-rectifier potassium channel regulatory subunit KCNS3

2

0

High-throughput

0.602

High

790185

HS3S2
Heparan sulfate glucosamine 3-O-sulfotransferase 2

2

0

High-throughput

0.602

High

790167

PIGC
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C

3

0

Small-scale

0.585

High

317057

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

2

0

Small-scale

0.576

High

790144

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

1

High-throughput

0.574

High

790160

LRRT1
Leucine-rich repeat transmembrane neuronal protein 1

2

1

High-throughput

0.574

High

790188

PCDB7
Protocadherin beta-7

2

2

High-throughput

0.574

High

790155

EREP1
Endosomal transmembrane epsin interactor 1

2

1

High-throughput

0.558

High

559894

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

1

High-throughput

0.536

High

790147

EREP3
Protein ENTREP3

1

1

High-throughput

0.536

High

790176

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

1

High-throughput

0.536

High

790179

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

270143

LRP3
Low-density lipoprotein receptor-related protein 3

1

0

High-throughput

0.513

High

303676

JTB
Protein JTB

1

0

High-throughput

0.513

High

790148

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.513

High

790150

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

0

High-throughput

0.513

High

790151

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

0

High-throughput

0.513

High

790157

PIGY
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y

1

0

Small-scale

0.513

High

790170

ZDH12
Palmitoyltransferase ZDHHC12

1

0

High-throughput

0.513

High

790171

TM169
Transmembrane protein 169

1

0

High-throughput

0.513

High

790173

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.513

High

790158

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.489

High

790169

I17RA
Interleukin-17 receptor A

1

1

High-throughput

0.489

High

790172

COX42
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial

1

1

High-throughput

0.489

High

790180

KCMB3
Calcium-activated potassium channel subunit beta-3

1

1

High-throughput

0.489

High

790182

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

1

High-throughput

0.489

High

790189

PCDA3
Protocadherin alpha-3

1

1

High-throughput

0.489

High

790154

MFS10
Major facilitator superfamily domain-containing protein 10

1

2

High-throughput

0.445

High

790156

S4A8
Electroneutral sodium bicarbonate exchanger 1

1

2

High-throughput

0.445

High

790163

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

1

High-throughput

0.445

High

790177

S12A9
Solute carrier family 12 member 9

1

2

High-throughput

0.445

High

790178

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

2

High-throughput

0.445

High

790181

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

1

High-throughput

0.445

High

790190

S4A7
Sodium bicarbonate cotransporter 3

1

2

High-throughput

0.445

High

790159

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

469416

ELNE
Neutrophil elastase

1

2

Small-scale

0.417

High

332120

I18RA
Interleukin-18 receptor accessory protein

2

0

High-throughput

0.328

High

596742

DPEP1
Dipeptidase 1

2

0

High-throughput

0.328

High

771540

TSP2
Thrombospondin-2

2

0

High-throughput

0.328

High

790149

CD83
CD83 antigen

2

0

High-throughput

0.328

High

790168

VWCE
von Willebrand factor C and EGF domain-containing protein

2

0

High-throughput

0.328

High

790183

NAGK
N-acetyl-D-glucosamine kinase

2

0

High-throughput

0.328

High

790152

TRAF1
TNF receptor-associated factor 1

2

0

High-throughput

0.324

High

390997

TRFL
Lactotransferrin

1

0

High-throughput

0.279

Low

711544

NK3R
Neuromedin-K receptor

1

0

High-throughput

0.279

Low

790161

I22R1
Interleukin-22 receptor subunit alpha-1

1

0

High-throughput

0.279

Low

790162

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

790164

HAVR2
Hepatitis A virus cellular receptor 2

1

0

High-throughput

0.279

Low

790187

O10H1
Olfactory receptor 10H1

1

0

High-throughput

0.279

Low

332621

LYPD3
Ly6/PLAUR domain-containing protein 3

1

0

High-throughput

0.249

Low

790186

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025