Protein: UTP20
Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6)

Gene: UTP20
Organism: Homo sapiens
Interactions: 130
UniProt ID: O75691

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

262191

SCN2B
Sodium channel regulatory subunit beta-2

4

3

High-throughput

0.691

High

291064

BASI
Basigin

3

1

High-throughput

0.667

High

291142

PD1L1
Programmed cell death 1 ligand 1

3

1

High-throughput

0.667

High

291141

SCN3B
Sodium channel regulatory subunit beta-3

3

3

High-throughput

0.662

High

291045

GLPB
Glycophorin-B

2

1

High-throughput

0.628

High

291052

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

2

High-throughput

0.628

High

291041

MYC
Myc proto-oncogene protein

3

0

High-throughput

0.613

High

291095

IF16
Gamma-interferon-inducible protein 16

2

1

High-throughput

0.611

High

291060

CD70
CD70 antigen

2

0

High-throughput

0.602

High

182434

GP182
G-protein coupled receptor 182

2

2

High-throughput

0.601

High

291053

TNR1B
Tumor necrosis factor receptor superfamily member 1B

2

2

High-throughput

0.601

High

291149

NPTN
Neuroplastin

2

1

High-throughput

0.601

High

291081

RS6
Small ribosomal subunit protein eS6

2

1

High-throughput

0.584

High

291106

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

1

High-throughput

0.574

High

291134

CLMP
CXADR-like membrane protein

2

1

High-throughput

0.574

High

291043

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

291096

PPR26
Protein phosphatase 1 regulatory subunit 26

1

0

Small-scale

0.569

High

291083

RS24
Small ribosomal subunit protein eS24

2

0

High-throughput

0.559

High

291137

ANLN
Anillin

2

0

High-throughput

0.559

High

291042

GLPA
Glycophorin-A

1

1

High-throughput

0.536

High

291061

CD80
T-lymphocyte activation antigen CD80

1

1

High-throughput

0.536

High

291066

MNDA
Myeloid cell nuclear differentiation antigen

1

1

High-throughput

0.536

High

291071

EFNA4
Ephrin-A4

1

1

High-throughput

0.536

High

291072

EFNA5
Ephrin-A5

1

1

High-throughput

0.536

High

291090

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.536

High

171968

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

1

High-throughput

0.515

High

291056

SFPQ
Splicing factor, proline- and glutamine-rich

1

1

High-throughput

0.515

High

291038

JTB
Protein JTB

1

0

High-throughput

0.513

High

291054

LMNB1
Lamin-B1

1

0

High-throughput

0.513

High

291067

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

291070

IMA5
Importin subunit alpha-5

1

0

High-throughput

0.513

High

291117

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.513

High

291121

TMM74
Transmembrane protein 74

1

0

High-throughput

0.513

High

291122

OPALI
Opalin

1

0

High-throughput

0.513

High

291130

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.513

High

291039

CSTN1
Calsyntenin-1

1

1

High-throughput

0.489

High

291088

FOXL1
Forkhead box protein L1

1

1

High-throughput

0.489

High

291131

CSTN2
Calsyntenin-2

1

1

High-throughput

0.489

High

126401

RHOD
Rho-related GTP-binding protein RhoD

1

9

High-throughput

0.479

High

140685

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

285004

EED
Polycomb protein EED

1

1

High-throughput

0.479

High

291047

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

291048

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

291049

RAC2
Ras-related C3 botulinum toxin substrate 2

1

5

High-throughput

0.479

High

291055

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.479

High

291059

PML
Protein PML

1

1

High-throughput

0.479

High

291068

CENPA
Histone H3-like centromeric protein A

1

1

High-throughput

0.479

High

291069

RND2
Rho-related GTP-binding protein RhoN

1

8

High-throughput

0.479

High

291074

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

291075

RAC3
Ras-related C3 botulinum toxin substrate 3

1

6

High-throughput

0.479

High

291076

CDC42
Cell division control protein 42 homolog

1

6

High-throughput

0.479

High

291078

RHOA
Transforming protein RhoA

1

7

High-throughput

0.479

High

291080

RHOB
Rho-related GTP-binding protein RhoB

1

7

High-throughput

0.479

High

291082

H4
Histone H4

1

1

High-throughput

0.479

High

291084

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

291085

RAC1
Ras-related C3 botulinum toxin substrate 1

1

6

High-throughput

0.479

High

291087

EXOSX
Exosome complex component 10

1

1

High-throughput

0.479

High

291089

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

291091

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

291093

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

291107

DHX40
Probable ATP-dependent RNA helicase DHX40

1

2

High-throughput

0.479

High

291113

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

291116

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

1

High-throughput

0.479

High

291119

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

291120

RHOV
Rho-related GTP-binding protein RhoV

1

6

High-throughput

0.479

High

291124

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

1

High-throughput

0.479

High

291125

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

1

High-throughput

0.479

High

291132

RHOJ
Rho-related GTP-binding protein RhoJ

1

7

High-throughput

0.479

High

291136

RHOF
Rho-related GTP-binding protein RhoF

1

8

High-throughput

0.479

High

291140

AATF
Protein AATF

1

1

High-throughput

0.479

High

128677

MEN1
Menin

1

0

High-throughput

0.458

High

190765

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

193927

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

217617

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

222588

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

271773

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

291040

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

291046

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

291050

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

291058

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

291062

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.458

High

291063

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

291065

COIL
Coilin

1

0

High-throughput

0.458

High

291079

RUXE
Small nuclear ribonucleoprotein E

1

0

High-throughput

0.458

High

291094

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

291099

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

291101

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

291103

GGYF2
GRB10-interacting GYF protein 2

1

0

High-throughput

0.458

High

291104

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

291109

NUP43
Nucleoporin Nup43

1

0

High-throughput

0.458

High

291111

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

291112

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

291114

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.458

High

291115

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

291118

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

291123

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

291126

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

291128

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

291133

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

291135

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

291138

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

291143

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

291144

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

291145

XPO7
Exportin-7

1

0

High-throughput

0.458

High

291148

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

291150

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.458

High

171376

S27A2
Long-chain fatty acid transport protein 2

1

1

High-throughput

0.445

High

291057

TNR5
Tumor necrosis factor receptor superfamily member 5

1

2

High-throughput

0.445

High

291077

CXCR4
C-X-C chemokine receptor type 4

1

1

High-throughput

0.445

High

291100

S27A4
Long-chain fatty acid transport protein 4

1

1

High-throughput

0.445

High

166229

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.426

High

291051

SDC1
Syndecan-1

1

0

High-throughput

0.426

High

291092

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

291097

FAXC
Failed axon connections homolog

1

0

High-throughput

0.426

High

291108

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.426

High

291127

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.426

High

291146

CC018
Uncharacterized protein C3orf18

2

0

High-throughput

0.313

High

208935

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.279

Low

291073

ARSF
Arylsulfatase F

1

0

High-throughput

0.279

Low

291086

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

291129

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

291139

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

156780

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

173795

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.249

Low

291102

LRC31
Leucine-rich repeat-containing protein 31

1

0

High-throughput

0.249

Low

291105

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

291147

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

291044

VTNC
Vitronectin

1

0

High-throughput

0.232

Low

291098

ANR22
Ankyrin repeat domain-containing protein 22

1

0

High-throughput

0.232

Low

291110

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025