Protein: RCAF1
GEL complex subunit OPTI (Obligate partner of TMCO1 insertase) (Rab5-interacting protein) (RIP5) (Respirasome Complex Assembly Factor 1)

Gene: RCAF1, RAB5IF
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q9BUV8

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0097250 - mitochondrial respirasome assembly
GO:0160063 - multi-pass transmembrane protein insertion into ER membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1326891

EMC5
ER membrane protein complex subunit 5

1

1

High-throughput

0.691

High

1414748

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.656

High

1308958

S22A9
Organic anion transporter 7

2

1

High-throughput

0.574

High

1414738

S22A4
Solute carrier family 22 member 4

1

1

High-throughput

0.536

High

630189

ACM3
Muscarinic acetylcholine receptor M3

1

0

High-throughput

0.518

High

1414741

ATD3A
ATPase family AAA domain-containing protein 3A

1

1

High-throughput

0.515

High

349705

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

1

0

High-throughput

0.513

High

699059

CALX
Calnexin

1

0

High-throughput

0.513

High

888979

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.513

High

1381335

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.513

High

1382173

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

184502

SURF4
Surfeit locus protein 4

1

0

High-throughput

0.493

High

184905

SPTC1
Serine palmitoyltransferase 1

1

0

High-throughput

0.493

High

292214

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.493

High

301961

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.493

High

348701

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.493

High

701902

ABCD3
ATP-binding cassette sub-family D member 3

1

0

High-throughput

0.493

High

1414743

HACD3
Very-long-chain

1

0

High-throughput

0.493

High

1414749

SSRG
Translocon-associated protein subunit gamma

1

0

High-throughput

0.493

High

141640

DDX3X
ATP-dependent RNA helicase DDX3X

1

1

High-throughput

0.479

High

1214771

ATD3B
ATPase family AAA domain-containing protein 3B

1

1

High-throughput

0.479

High

1414747

XPO7
Exportin-7

1

1

High-throughput

0.470

High

137804

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

275096

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

339288

MPC2
Mitochondrial pyruvate carrier 2

1

0

High-throughput

0.458

High

417718

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

418402

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

944319

TMM33
Transmembrane protein 33

1

0

High-throughput

0.458

High

1158278

RM23
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

1162530

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

1312743

RM41
Large ribosomal subunit protein mL41

1

0

High-throughput

0.458

High

1356868

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

0

High-throughput

0.458

High

1391282

CERS2
Ceramide synthase 2

1

0

High-throughput

0.458

High

1394476

ATPMK
ATP synthase F(0) complex subunit k, mitochondrial

1

0

High-throughput

0.458

High

608730

DDX5
Probable ATP-dependent RNA helicase DDX5

1

1

High-throughput

0.437

High

564319

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

1232116

VASN
Vasorin

1

0

High-throughput

0.426

High

1414742

TMM51
Transmembrane protein 51

3

0

High-throughput

0.347

High

1142524

PDCD1
Programmed cell death protein 1

2

0

High-throughput

0.328

High

212480

SPIT2
Kunitz-type protease inhibitor 2

2

0

High-throughput

0.318

High

253891

TPST2
Protein-tyrosine sulfotransferase 2

2

0

High-throughput

0.313

High

1407293

CML1
Chemerin-like receptor 1

2

0

High-throughput

0.313

High

1112419

MTMR2
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2

1

0

High-throughput

0.279

Low

1212296

TM63B
Mechanosensitive cation channel TMEM63B

1

0

High-throughput

0.279

Low

1249838

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.279

Low

1399050

TMM74
Transmembrane protein 74

1

0

High-throughput

0.279

Low

1414753

SO1B1
Solute carrier organic anion transporter family member 1B1

1

0

High-throughput

0.279

Low

158495

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.269

Low

211034

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.269

Low

903778

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.269

Low

1124034

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.269

Low

1358742

FACR1
Fatty acyl-CoA reductase 1

1

0

High-throughput

0.269

Low

1365743

GCN1
Stalled ribosome sensor GCN1

1

0

High-throughput

0.269

Low

1414740

FANCI
Fanconi anemia group I protein

1

0

High-throughput

0.269

Low

1414746

IPO11
Importin-11

1

0

High-throughput

0.269

Low

1414752

TNPO3
Transportin-3

1

0

High-throughput

0.269

Low

337017

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

High-throughput

0.249

Low

827256

ARL1
ADP-ribosylation factor-like protein 1

1

0

High-throughput

0.249

Low

910665

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

High-throughput

0.249

Low

1239287

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.249

Low

1241628

EBLN2
Endogenous Bornavirus-like nucleoprotein 2

1

0

High-throughput

0.249

Low

1323142

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

High-throughput

0.249

Low

1323448

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.249

Low

1329474

KTAP2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

1

0

High-throughput

0.249

Low

1414739

EHD4
EH domain-containing protein 4

1

0

High-throughput

0.249

Low

1414744

ATX10
Ataxin-10

1

0

High-throughput

0.249

Low

1414745

GCP4
Gamma-tubulin complex component 4

1

0

High-throughput

0.249

Low

1414750

ANKR6
Ankyrin repeat domain-containing protein 6

1

0

High-throughput

0.249

Low

1414751

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025