Protein: CTU1
Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (ATP-binding domain-containing protein 3) (Cancer-associated gene protein) (Cytoplasmic tRNA adenylyltransferase 1)

Gene: CTU1
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q7Z7A3

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002098 - tRNA wobble uridine modification
GO:0002143 - tRNA wobble position uridine thiolation
GO:0002144 - cytosolic tRNA wobble base thiouridylase complex
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

896570

VASP
Vasodilator-stimulated phosphoprotein

3

1

High-throughput

0.667

High

1280968

URM1
Ubiquitin-related modifier 1

2

3

Small-scale

0.651

High

1280969

THUM3
tRNA

2

1

High-throughput

0.628

High

1280972

GAN
Gigaxonin

2

1

High-throughput

0.628

High

1086168

CETN1
Centrin-1

2

0

High-throughput

0.602

High

291668

XRP2
Protein XRP2

2

0

High-throughput

0.585

High

1280980

FBX2
F-box only protein 2

2

0

High-throughput

0.576

High

553754

MYCL
Protein L-Myc

2

1

High-throughput

0.574

High

1280960

VWCE
von Willebrand factor C and EGF domain-containing protein

2

1

High-throughput

0.574

High

1280966

LBHD1
LBH domain-containing protein 1

2

1

High-throughput

0.574

High

1280979

TINAG
Tubulointerstitial nephritis antigen

2

1

High-throughput

0.574

High

1280974

RISC
Retinoid-inducible serine carboxypeptidase

2

1

High-throughput

0.549

High

407647

S100B
Protein S100-B

1

2

High-throughput

0.536

High

518610

RAP2A
Ras-related protein Rap-2a

1

2

High-throughput

0.536

High

1093262

FLII
Protein flightless-1 homolog

1

1

High-throughput

0.536

High

1180677

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

3

Small-scale

0.536

High

1280959

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

1

High-throughput

0.536

High

1280967

ACBD6
Acyl-CoA-binding domain-containing protein 6

1

2

High-throughput

0.536

High

1280975

SPHK1
Sphingosine kinase 1

1

1

High-throughput

0.536

High

302874

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

1

High-throughput

0.533

High

191354

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.513

High

348590

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.513

High

1280958

RAB24
Ras-related protein Rab-24

1

0

High-throughput

0.513

High

1280976

AKA7G
A-kinase anchor protein 7 isoform gamma

1

0

High-throughput

0.513

High

1280978

FKBPL
FK506-binding protein-like

1

0

High-throughput

0.513

High

824

A0A096LNW4
PRAME family member 9

1

1

High-throughput

0.489

High

706192

S10A2
Protein S100-A2

1

2

High-throughput

0.489

High

945939

LOXL3
Lysyl oxidase homolog 3

1

1

High-throughput

0.489

High

1098701

CHIT1
Chitotriosidase-1

1

1

High-throughput

0.489

High

1159391

ECM1
Extracellular matrix protein 1

1

1

High-throughput

0.489

High

1213633

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

1

High-throughput

0.489

High

1216375

FAXC
Failed axon connections homolog

1

1

High-throughput

0.489

High

1280951

ZN444
Zinc finger protein 444

1

1

High-throughput

0.489

High

1280953

KCD17
BTB/POZ domain-containing protein KCTD17

1

1

High-throughput

0.489

High

1280961

ZN414
Zinc finger protein 414

1

1

High-throughput

0.489

High

1280962

HIPL1
HHIP-like protein 1

1

1

High-throughput

0.489

High

1280964

RB40C
Ras-related protein Rab-40C

1

1

High-throughput

0.489

High

1280982

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

2

High-throughput

0.489

High

532152

HEM4
Uroporphyrinogen-III synthase

1

1

High-throughput

0.479

High

761741

HSP74
Heat shock 70 kDa protein 4

1

1

Small-scale

0.479

High

1113548

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1280965

MMS19
MMS19 nucleotide excision repair protein homolog

1

1

High-throughput

0.479

High

1280983

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

1

High-throughput

0.479

High

242145

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

787561

TNR3
Tumor necrosis factor receptor superfamily member 3

1

2

High-throughput

0.437

High

1280950

CCNJL
Cyclin-J-like protein

1

1

High-throughput

0.437

High

1280973

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

516199

HS71B
Heat shock 70 kDa protein 1B

1

0

Small-scale

0.426

High

635338

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.426

High

1280954

EIF1A
Probable RNA-binding protein EIF1AD

1

0

High-throughput

0.426

High

848148

MAGA1
Melanoma-associated antigen 1

3

0

High-throughput

0.347

High

1216126

FHL5
Four and a half LIM domains protein 5

3

0

High-throughput

0.347

High

1280949

ECHD2
Enoyl-CoA hydratase domain-containing protein 2, mitochondrial

3

0

High-throughput

0.347

High

192107

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.328

High

1085133

SCRN1
Secernin-1

2

0

High-throughput

0.328

High

239109

ZNRD2
Protein ZNRD2

2

0

High-throughput

0.313

High

190413

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

485944

GIP
Gastric inhibitory polypeptide

1

0

High-throughput

0.279

Low

582346

ARSA
Arylsulfatase A

1

0

High-throughput

0.279

Low

705440

GRN
Progranulin

1

0

High-throughput

0.279

Low

933191

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.279

Low

1103096

MFAP5
Microfibrillar-associated protein 5

1

0

High-throughput

0.279

Low

1200484

H1BP3
HCLS1-binding protein 3

1

0

High-throughput

0.279

Low

1280952

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.279

Low

1280956

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.279

Low

1280957

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.279

Low

1280971

IL25
Interleukin-25

1

0

High-throughput

0.279

Low

1280984

GPSM3
G-protein-signaling modulator 3

1

0

High-throughput

0.279

Low

212440

SPIT2
Kunitz-type protease inhibitor 2

1

0

High-throughput

0.249

Low

1280955

MINY2
Ubiquitin carboxyl-terminal hydrolase MINDY-2

1

0

High-throughput

0.249

Low

1280963

DAA10
Dynein axonemal assembly factor 10

1

0

High-throughput

0.249

Low

1280970

NYX
Nyctalopin

1

0

High-throughput

0.249

Low

1280977

BAHC1
BAH and coiled-coil domain-containing protein 1

1

0

High-throughput

0.249

Low

1280985

SNX11
Sorting nexin-11

1

0

High-throughput

0.249

Low

1047606

NOTC2
Neurogenic locus notch homolog protein 2

1

0

High-throughput

0.232

Low

1280981

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025