Protein: PERM
Myeloperoxidase (MPO) (EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain]

Gene: PERM, MPO
Organism: Homo sapiens
Interactions: 67
UniProt ID: P05164

Gene Ontology (top 5):
GO:0001878 - response to yeast
GO:0002149 - hypochlorous acid biosynthetic process
GO:0002679 - respiratory burst involved in defense response
GO:0003682 - chromatin binding
GO:0004601 - peroxidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

425754

EGFL8
Epidermal growth factor-like protein 8

2

5

High-throughput

0.776

High

425730

ICE2
Little elongation complex subunit 2

3

0

High-throughput

0.638

High

425720

HNRPK
Heterogeneous nuclear ribonucleoprotein K

2

1

High-throughput

0.601

High

210681

KLK10
Kallikrein-10

1

1

High-throughput

0.536

High

425714

GSK3B
Glycogen synthase kinase-3 beta

1

2

High-throughput

0.536

High

425734

MAEA
E3 ubiquitin-protein transferase MAEA

1

1

High-throughput

0.536

High

425736

ELOA2
Elongin-A2

1

1

High-throughput

0.536

High

425751

SRPK1
SRSF protein kinase 1

1

1

High-throughput

0.536

High

425709

CALR
Calreticulin

1

2

Small-scale

0.527

High

191899

MAGB4
Melanoma-associated antigen B4

1

0

High-throughput

0.513

High

210162

IRAK2
Interleukin-1 receptor-associated kinase-like 2

1

0

High-throughput

0.513

High

425717

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

0

High-throughput

0.513

High

425727

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.513

High

425740

LRC17
Leucine-rich repeat-containing protein 17

1

0

High-throughput

0.513

High

425742

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.513

High

425743

ITLN2
Intelectin-2

1

0

High-throughput

0.513

High

425747

ERO1A
ERO1-like protein alpha

1

0

High-throughput

0.513

High

425756

CP343
Cytochrome P450 3A43

1

0

High-throughput

0.513

High

425759

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

High-throughput

0.493

High

67421

GOG8A
Golgin subfamily A member 8A

1

2

High-throughput

0.489

High

425712

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.489

High

425719

STX17
Syntaxin-17

1

1

High-throughput

0.489

High

425721

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

1

High-throughput

0.489

High

425710

PROP
Properdin

1

0

Small-scale

0.480

High

425726

TP4A2
Protein tyrosine phosphatase type IVA 2

1

0

Small-scale

0.480

High

238349

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.479

High

272599

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

2

High-throughput

0.479

High

370913

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

388156

GLPA
Glycophorin-A

1

1

Small-scale

0.479

High

388812

CO9
Complement component C9 [Cleaved into: Complement component C9a; Complement component C9b]

1

1

Small-scale

0.479

High

425708

PRTN3
Myeloblastin

1

1

High-throughput

0.479

High

425725

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

2

Small-scale

0.479

High

425744

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

425750

RANB9
Ran-binding protein 9

1

1

High-throughput

0.479

High

425752

EYA1
Protein phosphatase EYA1

1

1

High-throughput

0.479

High

425757

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

1

High-throughput

0.479

High

277252

PITX3
Pituitary homeobox 3

1

0

Small-scale

0.458

High

369808

CO3
Complement C3

1

0

Small-scale

0.458

High

388353

B3AT
Band 3 anion transport protein

1

0

Small-scale

0.458

High

390980

TRFL
Lactotransferrin

1

0

High-throughput

0.458

High

425711

PML
Protein PML

1

0

High-throughput

0.458

High

425715

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

0

Small-scale

0.458

High

425723

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

425724

RUNX1
Runt-related transcription factor 1

1

0

Small-scale

0.458

High

425755

RSRP1
Arginine/serine-rich protein 1

1

1

High-throughput

0.445

High

425707

GLPB
Glycophorin-B

1

1

Small-scale

0.437

High

425738

FBXW8
F-box/WD repeat-containing protein 8

1

1

High-throughput

0.437

High

425718

MAT1
CDK-activating kinase assembly factor MAT1

1

0

High-throughput

0.426

High

425739

CD177
CD177 antigen

1

0

Small-scale

0.426

High

425713

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.408

High

425735

PRRT2
Proline-rich transmembrane protein 2

1

1

High-throughput

0.407

High

425732

PLB1
Phospholipase B1, membrane-associated

2

0

High-throughput

0.328

High

425737

APCD1
Protein APCDD1

2

0

High-throughput

0.328

High

425741

FRMD1
FERM domain-containing protein 1

2

0

High-throughput

0.328

High

354012

CX001
Putative transmembrane protein CXorf1

1

0

High-throughput

0.279

Low

425716

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.279

Low

425722

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.279

Low

425729

H1BP3
HCLS1-binding protein 3

1

0

High-throughput

0.279

Low

425746

PF21B
PHD finger protein 21B

1

0

High-throughput

0.279

Low

425748

SMIM8
Small integral membrane protein 8

1

0

High-throughput

0.279

Low

425753

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

425758

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.279

Low

425745

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.269

Low

425728

TR16L
Tripartite motif-containing protein 16-like protein

1

0

High-throughput

0.232

Low

425731

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

425733

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low

425749

CI085
Uncharacterized protein C9orf85

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025