Protein: DDAH2
Putative hydrolase DDAH2 (EC 3.-.-.-) (DDAHII) (Inactive N(G),N(G)-dimethylarginine dimethylaminohydrolase 2) (DDAH-2) (Inactive dimethylarginine dimethylaminohydrolase 2) (Protein G6a) (S-phase protein)

Gene: DDAH2
Organism: Homo sapiens
Interactions: 56
UniProt ID: O95865

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0016787 - hydrolase activity
GO:0043066 - negative regulation of apoptotic process
GO:0045429 - positive regulation of nitric oxide biosynthetic process
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

217356

E41L2
Band 4.1-like protein 2

4

4

High-throughput

0.691

High

350294

PCH2
Pachytene checkpoint protein 2 homolog

4

1

High-throughput

0.642

High

314942

DDAH1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

3

0

High-throughput

0.638

High

350307

E41L1
Band 4.1-like protein 1

4

4

High-throughput

0.630

High

350312

E41L3
Band 4.1-like protein 3

3

4

High-throughput

0.609

High

350289

ACTN3
Alpha-actinin-3

2

0

High-throughput

0.580

High

350290

VAC14
Protein VAC14 homolog

2

1

High-throughput

0.559

High

350276

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

350297

S2535
Solute carrier family 25 member 35

1

0

High-throughput

0.513

High

350293

KS6A1
Ribosomal protein S6 kinase alpha-1

1

1

High-throughput

0.508

High

350295

T22D1
TSC22 domain family protein 1

1

1

High-throughput

0.508

High

350286

DAOA
D-amino acid oxidase regulator

1

0

High-throughput

0.493

High

350272

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

High-throughput

0.486

High

350280

ANXA7
Annexin A7

1

0

High-throughput

0.486

High

350287

RAP1B
Ras-related protein Rap-1b

1

0

High-throughput

0.486

High

350300

CDC73
Parafibromin

1

0

High-throughput

0.486

High

287639

KS6A5
Ribosomal protein S6 kinase alpha-5

1

1

High-throughput

0.464

High

350306

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

1

2

High-throughput

0.464

High

350269

FINC
Fibronectin

1

0

High-throughput

0.458

High

350279

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.458

High

350273

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

96595

E9PAV9
G patch domain-containing protein 4

1

1

High-throughput

0.437

High

105038

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

350301

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

350270

PRIO
Major prion protein

1

0

High-throughput

0.426

High

350305

GMPPA
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha

1

0

High-throughput

0.426

High

69921

A8KAG1
G patch domain-containing protein 4

1

1

High-throughput

0.407

High

350274

EPB41
Protein 4.1

1

4

High-throughput

0.407

High

185327

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

3

0

High-throughput

0.347

High

350283

SOX2
Transcription factor SOX-2

3

0

High-throughput

0.347

High

350284

HCFC1
Host cell factor 1

3

0

High-throughput

0.347

High

350285

ICLN
Methylosome subunit pICln

3

0

High-throughput

0.347

High

302033

SEGN
Secretagogin

2

0

Small-scale

0.322

High

225513

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.316

High

350302

NOXA1
NADPH oxidase activator 1

2

0

High-throughput

0.316

High

350303

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

2

0

High-throughput

0.316

High

350309

FANCL
E3 ubiquitin-protein ligase FANCL

2

0

High-throughput

0.316

High

131051

TULP2
Tubby-related protein 2

1

0

High-throughput

0.279

Low

350277

EGLN
Endoglin

1

0

High-throughput

0.279

Low

350281

IKBA
NF-kappa-B inhibitor alpha

1

0

High-throughput

0.279

Low

350299

HYI
Putative hydroxypyruvate isomerase

1

0

High-throughput

0.279

Low

350304

TRI41
E3 ubiquitin-protein ligase TRIM41

1

0

High-throughput

0.279

Low

350288

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.269

Low

164678

TNF11
Tumor necrosis factor ligand superfamily member 11

1

0

High-throughput

0.265

Low

332124

GA45G
Growth arrest and DNA damage-inducible protein GADD45 gamma

1

0

High-throughput

0.265

Low

350271

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.265

Low

350275

CDK4
Cyclin-dependent kinase 4

1

0

High-throughput

0.265

Low

350278

RCC1
Regulator of chromosome condensation

1

0

High-throughput

0.265

Low

350282

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.265

Low

350291

STK3
Serine/threonine-protein kinase 3

1

0

High-throughput

0.265

Low

350292

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.265

Low

350296

SMN
Survival motor neuron protein

1

0

High-throughput

0.265

Low

350308

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

1

0

High-throughput

0.265

Low

350310

M3K20
Mitogen-activated protein kinase kinase kinase 20

1

0

High-throughput

0.265

Low

350311

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.265

Low

350298

PKHO1
Pleckstrin homology domain-containing family O member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025