Protein: DPOE2
DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B)

Gene: DPOE2, POLE2
Organism: Homo sapiens
Interactions: 52
UniProt ID: P56282

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005654 - nucleoplasm
GO:0006260 - DNA replication
GO:0006261 - DNA-templated DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

940484

DPOE1
DNA polymerase epsilon catalytic subunit A

9

4

Small-scale

0.969

High

940506

DPOE3
DNA polymerase epsilon subunit 3

3

1

Small-scale

0.689

High

940505

DPOE4
DNA polymerase epsilon subunit 4

3

2

Small-scale

0.678

High

571909

TRI27
Zinc finger protein RFP

4

0

High-throughput

0.668

High

940500

DNJC7
DnaJ homolog subfamily C member 7

3

0

High-throughput

0.638

High

940512

KLK5
Kallikrein-5

3

1

High-throughput

0.609

High

940503

CP4FC
Cytochrome P450 4F12

2

0

High-throughput

0.595

High

354214

ZBED1
E3 SUMO-protein ligase ZBED1

2

0

High-throughput

0.580

High

940504

EXOS4
Exosome complex component RRP41

2

0

High-throughput

0.580

High

940508

KLK11
Kallikrein-11

2

1

High-throughput

0.558

High

912764

AGFG1
Arf-GAP domain and FG repeat-containing protein 1

1

0

High-throughput

0.549

High

940483

REL
Proto-oncogene c-Rel

1

0

High-throughput

0.549

High

940482

TLE1
Transducin-like enhancer protein 1

1

0

High-throughput

0.518

High

940492

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.518

High

940513

V9HWB8
Pyruvate kinase

1

1

High-throughput

0.515

High

940495

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

940511

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.513

High

134623

SAP18
Histone deacetylase complex subunit SAP18

1

0

Small-scale

0.504

High

940480

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.494

High

940490

TTC9C
Tetratricopeptide repeat protein 9C

1

1

High-throughput

0.489

High

573047

KPYM
Pyruvate kinase PKM

1

1

High-throughput

0.481

High

507738

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

298588

RAD17
Cell cycle checkpoint protein RAD17

1

1

Small-scale

0.479

High

940501

PCGF1
Polycomb group RING finger protein 1

1

1

High-throughput

0.479

High

940487

BI2L2
BAR/IMD domain-containing adapter protein 2-like 2

1

0

High-throughput

0.460

High

212382

SPIT2
Kunitz-type protease inhibitor 2

1

0

High-throughput

0.458

High

830432

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

940481

TFAP4
Transcription factor AP-4

1

0

Small-scale

0.458

High

940494

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

940496

LRC46
Leucine-rich repeat-containing protein 46

4

0

High-throughput

0.360

High

940485

MARE1
Microtubule-associated protein RP/EB family member 1

3

0

High-throughput

0.352

High

821704

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.328

High

940479

ARL4C
ADP-ribosylation factor-like protein 4C

2

0

High-throughput

0.328

High

940486

CF141
Uncharacterized protein C6orf141

2

0

High-throughput

0.328

High

940493

SNX21
Sorting nexin-21

2

0

High-throughput

0.328

High

940497

TET5A
Terminal nucleotidyltransferase 5A

2

0

High-throughput

0.328

High

940498

MERB1
bMERB domain-containing protein 1

2

0

High-throughput

0.328

High

868663

LEG7
Galectin-7

2

0

High-throughput

0.318

High

250230

VINEX
Vinexin

2

0

High-throughput

0.316

High

940488

ZN620
Zinc finger protein 620

2

0

High-throughput

0.316

High

940509

UBQL2
Ubiquilin-2

2

0

High-throughput

0.316

High

940499

TBX15
T-box transcription factor TBX15

1

0

High-throughput

0.299

High

940510

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

74459

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.279

Low

131056

TULP2
Tubby-related protein 2

1

0

High-throughput

0.279

Low

486551

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.279

Low

859752

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.279

Low

940489

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

940491

ASB11
Ankyrin repeat and SOCS box protein 11

1

0

High-throughput

0.249

Low

940502

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

940507

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

0

High-throughput

0.249

Low

591256

CD44
CD44 antigen

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025