Protein: ZSWM8
Zinc finger SWIM domain-containing protein 8

Gene: ZSWM8, ZSWIM8
Organism: Homo sapiens
Interactions: 76
UniProt ID: A7E2V4

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins
GO:0008270 - zinc ion binding
GO:0016567 - protein ubiquitination
GO:0031462 - Cul2-RING ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

67471

CUL3
Cullin-3

4

0

Small-scale

0.653

High

67463

KC1E
Casein kinase I isoform epsilon

2

2

High-throughput

0.628

High

67515

ASB3
Ankyrin repeat and SOCS box protein 3

2

0

High-throughput

0.602

High

67462

KC1D
Casein kinase I isoform delta

2

2

High-throughput

0.601

High

67473

ELOB
Elongin-B

2

2

Small-scale

0.584

High

67510

AGO2
Protein argonaute-2

2

1

Small-scale

0.584

High

67469

KC1G2
Casein kinase I isoform gamma-2

1

2

High-throughput

0.536

High

67495

AURKB
Aurora kinase B

1

1

High-throughput

0.536

High

67505

TXNIP
Thioredoxin-interacting protein

1

1

High-throughput

0.536

High

67508

AGO4
Protein argonaute-4

1

1

High-throughput

0.536

High

67467

ANM2
Protein arginine N-methyltransferase 2

1

0

High-throughput

0.518

High

67446

SOCS1
Suppressor of cytokine signaling 1

1

0

High-throughput

0.513

High

67450

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

67468

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.513

High

67475

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.513

High

67483

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

67489

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

0

High-throughput

0.513

High

67494

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

67500

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

67502

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

67465

ATX1
Ataxin-1

1

1

High-throughput

0.508

High

67486

ARRD2
Arrestin domain-containing protein 2

1

1

High-throughput

0.489

High

67491

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.489

High

67492

FGF14
Fibroblast growth factor 14

1

1

High-throughput

0.489

High

67511

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

1

High-throughput

0.489

High

67443

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

67464

PLK1
Serine/threonine-protein kinase PLK1

1

1

High-throughput

0.479

High

67472

ELOC
Elongin-C

1

1

Small-scale

0.479

High

67445

XPO1
Exportin-1

1

0

High-throughput

0.458

High

67454

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

67458

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

67459

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

67461

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

67478

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

67488

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

67493

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

67506

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

67507

SP110
Sp110 nuclear body protein

1

0

High-throughput

0.458

High

67444

S27A2
Long-chain fatty acid transport protein 2

1

2

High-throughput

0.445

High

67455

ATX1L
Ataxin-1-like

1

1

High-throughput

0.439

High

67496

SPTCS
Spatacsin

1

0

Small-scale

0.438

High

67474

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

67480

RABEK
Rab9 effector protein with kelch motifs

1

0

High-throughput

0.426

High

67481

STING
Stimulator of interferon genes protein

1

0

Small-scale

0.426

High

67476

S27A1
Long-chain fatty acid transport protein 1

1

2

High-throughput

0.407

High

67487

NET5
Netrin-5

1

1

High-throughput

0.407

High

67514

S27A6
Long-chain fatty acid transport protein 6

1

2

High-throughput

0.407

High

67456

PRG2
Bone marrow proteoglycan

3

0

High-throughput

0.347

High

67501

RM04
Large ribosomal subunit protein uL4m

3

0

High-throughput

0.347

High

67497

JPH4
Junctophilin-4

3

0

High-throughput

0.345

High

67441

TULP2
Tubby-related protein 2

2

0

High-throughput

0.328

High

67452

NOE2
Noelin-2

2

0

High-throughput

0.328

High

67499

DCR1C
Protein artemis

2

0

High-throughput

0.318

High

67503

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

0

High-throughput

0.282

High

66779

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

0

High-throughput

0.279

Low

67447

NUAK1
NUAK family SNF1-like kinase 1

1

0

High-throughput

0.279

Low

67448

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.279

Low

67482

CLASR
CLK4-associating serine/arginine rich protein

1

0

High-throughput

0.279

Low

67484

TSYL6
Testis-specific Y-encoded-like protein 6

1

0

High-throughput

0.279

Low

67512

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

67449

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.269

Low

67466

ATN1
Atrophin-1

1

0

High-throughput

0.265

Low

67451

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

67453

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

67457

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

67460

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

67470

PLD1
Phospholipase D1

1

0

High-throughput

0.249

Low

67479

CE128
Centrosomal protein of 128 kDa

1

0

High-throughput

0.249

Low

67490

DAZL
Deleted in azoospermia-like

1

0

High-throughput

0.249

Low

67498

YI001
Uncharacterized protein FLJ30774

1

0

High-throughput

0.249

Low

67509

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.249

Low

67513

R3HD2
R3H domain-containing protein 2

1

0

High-throughput

0.249

Low

67442

WNT9A
Protein Wnt-9a

1

0

High-throughput

0.232

Low

67477

PKHG7
Pleckstrin homology domain-containing family G member 7

1

0

High-throughput

0.232

Low

67485

CI163
Uncharacterized protein C9orf163

1

0

High-throughput

0.232

Low

67504

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025