Protein: RMP
Unconventional prefoldin RPB5 interactor 1 (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein)

Gene: RMP, URI1
Organism: Homo sapiens
Interactions: 162
UniProt ID: O94763

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000993 - RNA polymerase II complex binding
GO:0001558 - regulation of cell growth
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

316458

PFD2
Prefoldin subunit 2

10

5

Small-scale

0.969

High

316456

UXT
Protein UXT

7

2

Small-scale

0.967

High

182066

PFD6
Prefoldin subunit 6

5

6

Small-scale

0.915

High

316449

PDRG1
p53 and DNA damage-regulated protein 1

4

2

Small-scale

0.873

High

316333

RMP
Unconventional prefoldin RPB5 interactor 1

2

2

Small-scale

0.768

High

316348

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

12

1

Small-scale

0.757

High

316362

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

11

9

Small-scale

0.757

High

316376

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

9

9

Small-scale

0.755

High

316429

PFD5
Prefoldin subunit 5

2

1

Small-scale

0.754

High

316463

RUVB1
RuvB-like 1

10

2

Small-scale

0.754

High

316462

RUVB2
RuvB-like 2

10

2

Small-scale

0.752

High

316439

RPAP3
RNA polymerase II-associated protein 3

9

4

Small-scale

0.751

High

316453

PIHD1
PIH1 domain-containing protein 1

9

0

Small-scale

0.718

High

316352

RPB1
DNA-directed RNA polymerase II subunit RPB1

5

3

Small-scale

0.706

High

316426

DAA10
Dynein axonemal assembly factor 10

5

1

Small-scale

0.702

High

316448

PFD4
Prefoldin subunit 4

1

3

High-throughput

0.691

High

316369

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

4

1

High-throughput

0.691

High

316409

SKAP1
Src kinase-associated phosphoprotein 1

4

1

High-throughput

0.691

High

180193

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

4

2

Small-scale

0.686

High

316334

RPA1
DNA-directed RNA polymerase I subunit RPA1

4

3

Small-scale

0.686

High

316451

RPC2
DNA-directed RNA polymerase III subunit RPC2

4

3

Small-scale

0.686

High

316377

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

3

9

Small-scale

0.667

High

316450

RPC5
DNA-directed RNA polymerase III subunit RPC5

4

0

Small-scale

0.664

High

316412

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

4

0

High-throughput

0.657

High

316354

RPB2
DNA-directed RNA polymerase II subunit RPB2

3

3

High-throughput

0.656

High

316368

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

3

1

Small-scale

0.656

High

316465

RPC10
DNA-directed RNA polymerase III subunit RPC10

3

2

High-throughput

0.650

High

164990

RPC1
DNA-directed RNA polymerase III subunit RPC1

3

3

Small-scale

0.640

High

316349

SCP2
Sterol carrier protein 2

3

0

High-throughput

0.638

High

316388

TEBP
Prostaglandin E synthase 3

3

0

High-throughput

0.638

High

316447

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

3

2

Small-scale

0.633

High

316338

RPC4
DNA-directed RNA polymerase III subunit RPC4

3

0

Small-scale

0.628

High

316385

TIF1B
Transcription intermediary factor 1-beta

2

1

Small-scale

0.624

High

316404

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

2

1

High-throughput

0.611

High

316438

ASB7
Ankyrin repeat and SOCS box protein 7

2

0

High-throughput

0.602

High

316459

GPN3
GPN-loop GTPase 3

3

1

Small-scale

0.593

High

302718

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

8

High-throughput

0.586

High

316345

T2FB
General transcription factor IIF subunit 2

2

0

Small-scale

0.585

High

316370

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

2

0

High-throughput

0.585

High

316381

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

0

High-throughput

0.585

High

316347

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

2

High-throughput

0.584

High

316400

PRP8
Pre-mRNA-processing-splicing factor 8

2

1

High-throughput

0.584

High

316446

DMAP1
DNA methyltransferase 1-associated protein 1

1

1

Small-scale

0.573

High

185303

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

Small-scale

0.554

High

316346

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

0

High-throughput

0.537

High

316364

GRK6
G protein-coupled receptor kinase 6

1

1

High-throughput

0.536

High

316367

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.536

High

316401

PKN3
Serine/threonine-protein kinase N3

1

2

High-throughput

0.536

High

316403

KSR2
Kinase suppressor of Ras 2

1

1

High-throughput

0.536

High

316419

REQU
Zinc finger protein ubi-d4

1

1

High-throughput

0.536

High

316437

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

3

High-throughput

0.536

High

139382

VMA5A
von Willebrand factor A domain-containing protein 5A

1

0

High-throughput

0.513

High

208007

TTI1
TELO2-interacting protein 1 homolog

1

0

Small-scale

0.513

High

316340

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.513

High

316343

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

316390

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

0

High-throughput

0.513

High

316422

TRI52
E3 ubiquitin-protein ligase TRIM52

1

0

High-throughput

0.513

High

316425

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.513

High

316452

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.513

High

316468

COPG1
Coatomer subunit gamma-1

1

0

High-throughput

0.513

High

316359

T2FA
General transcription factor IIF subunit 1

1

0

Small-scale

0.512

High

316342

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

2

1

High-throughput

0.504

High

316351

KS6B1
Ribosomal protein S6 kinase beta-1

1

1

Small-scale

0.501

High

316356

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

Small-scale

0.501

High

316366

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

3

High-throughput

0.501

High

316424

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

3

High-throughput

0.501

High

316337

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

124701

AIP
AH receptor-interacting protein

1

2

High-throughput

0.479

High

131636

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

High-throughput

0.479

High

165729

PPE2
Serine/threonine-protein phosphatase with EF-hands 2

1

10

High-throughput

0.479

High

172343

XPO1
Exportin-1

1

2

High-throughput

0.479

High

276653

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

2

High-throughput

0.479

High

314967

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

316335

HERC2
E3 ubiquitin-protein ligase HERC2

1

4

High-throughput

0.479

High

316358

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

316361

VGFR3
Vascular endothelial growth factor receptor 3

1

1

High-throughput

0.479

High

316363

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

2

High-throughput

0.479

High

316365

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

1

Small-scale

0.479

High

316373

TPTE
Putative tyrosine-protein phosphatase TPTE

1

1

High-throughput

0.479

High

316374

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

2

High-throughput

0.479

High

316378

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

1

High-throughput

0.479

High

316379

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

4

Small-scale

0.479

High

316382

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

4

Small-scale

0.479

High

316383

HSF2
Heat shock factor protein 2

1

1

High-throughput

0.479

High

316386

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

3

High-throughput

0.479

High

316393

BRDT
Bromodomain testis-specific protein

1

1

High-throughput

0.479

High

316394

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

2

High-throughput

0.479

High

316405

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

316406

SPT6H
Transcription elongation factor SPT6

1

1

Small-scale

0.479

High

316417

TSC1
Hamartin

1

2

High-throughput

0.479

High

316428

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

2

High-throughput

0.479

High

316430

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

2

High-throughput

0.479

High

316431

MEP50
Methylosome protein WDR77

1

6

High-throughput

0.479

High

316441

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

3

High-throughput

0.479

High

316444

GPN1
GPN-loop GTPase 1

1

1

High-throughput

0.479

High

316455

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

2

High-throughput

0.479

High

316460

XPO7
Exportin-7

1

2

High-throughput

0.479

High

316467

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

1

High-throughput

0.479

High

137891

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

184256

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

190770

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

192767

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.458

High

258689

DNJA2
DnaJ homolog subfamily A member 2

1

0

Small-scale

0.458

High

287425

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.458

High

289897

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

316336

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

Small-scale

0.458

High

316339

K1C18
Keratin, type I cytoskeletal 18

1

0

Small-scale

0.458

High

316344

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

316353

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

Small-scale

0.458

High

316355

METK2
S-adenosylmethionine synthase isoform type-2

1

0

Small-scale

0.458

High

316357

1433B
14-3-3 protein beta/alpha

1

0

Small-scale

0.458

High

316371

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

Small-scale

0.458

High

316375

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

316384

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.458

High

316387

KEAP1
Kelch-like ECH-associated protein 1

1

0

Small-scale

0.458

High

316389

PCBP2
Poly(rC)-binding protein 2

1

0

Small-scale

0.458

High

316391

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.458

High

316407

DET1
DET1 homolog

1

0

High-throughput

0.458

High

316408

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

Small-scale

0.458

High

316410

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.458

High

316418

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

316420

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

Small-scale

0.458

High

316427

BROMI
Protein broad-minded

1

0

Small-scale

0.458

High

316432

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

0

High-throughput

0.458

High

316434

NOC4L
Nucleolar complex protein 4 homolog

1

0

Small-scale

0.458

High

316436

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

316440

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

316443

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

316454

TBCD7
TBC1 domain family member 7

1

0

High-throughput

0.458

High

316464

NOP58
Nucleolar protein 58

1

0

Small-scale

0.458

High

316466

PKP3
Plakophilin-3

1

0

Small-scale

0.458

High

316360

MYH9
Myosin-9

1

1

Small-scale

0.445

High

316380

ACTA
Actin, aortic smooth muscle

1

2

Small-scale

0.445

High

316396

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.445

High

316399

CDC73
Parafibromin

1

1

Small-scale

0.445

High

316402

CTR9
RNA polymerase-associated protein CTR9 homolog

1

2

Small-scale

0.445

High

316421

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

6

High-throughput

0.445

High

316350

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.437

High

316413

FBXL6
F-box/LRR-repeat protein 6

1

1

High-throughput

0.437

High

316442

Q9HAV2
Heat shock transcription factor 1

1

1

High-throughput

0.437

High

159442

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.426

High

316341

RPC22
Protein POLR1D, isoform 2

1

0

High-throughput

0.426

High

316372

S12A3
Solute carrier family 12 member 3

1

0

High-throughput

0.426

High

316414

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

Small-scale

0.426

High

316415

LEO1
RNA polymerase-associated protein LEO1

1

0

Small-scale

0.426

High

316445

RAB18
Ras-related protein Rab-18

1

0

High-throughput

0.426

High

316461

STAP1
Signal-transducing adaptor protein 1

1

0

Small-scale

0.426

High

70885

ZBBX
Zinc finger B-box domain-containing protein 1

2

0

High-throughput

0.328

High

316395

CHIC1
Cysteine-rich hydrophobic domain-containing protein 1

1

0

High-throughput

0.279

Low

316416

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

316433

PTSS2
Phosphatidylserine synthase 2

1

0

High-throughput

0.279

Low

316457

ZNHI2
Zinc finger HIT domain-containing protein 2

1

0

High-throughput

0.269

Low

76505

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

0

High-throughput

0.249

Low

168792

PLD2
Phospholipase D2

1

0

High-throughput

0.249

Low

316392

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

0

High-throughput

0.249

Low

316397

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.249

Low

316398

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.249

Low

316411

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.249

Low

316435

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.249

Low

62433

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low

316423

CC120
Coiled-coil domain-containing protein 120

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025