Protein: ADPPT
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (EC 2.7.8.7) (4'-phosphopantetheinyl transferase) (Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase) (AASD-PPT) (LYS5 ortholog)

Gene: ADPPT, AASDHPPT
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q9NRN7

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0005829 - cytosol
GO:0008897 - holo-[acyl-carrier-protein] synthase activity
GO:0009258 - 10-formyltetrahydrofolate catabolic process
GO:0015939 - pantothenate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1090942

TRAF2
TNF receptor-associated factor 2

4

0

High-throughput

0.675

High

506994

POTEI
POTE ankyrin domain family member I

3

2

High-throughput

0.667

High

1448739

PPR3C
Protein phosphatase 1 regulatory subunit 3C

2

0

High-throughput

0.602

High

1448730

ADPPT
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

1

0

High-throughput

0.586

High

243046

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

1048334

LGUL
Lactoylglutathione lyase

2

0

High-throughput

0.559

High

1149384

STIL
SCL-interrupting locus protein

2

0

High-throughput

0.559

High

1307802

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

0

High-throughput

0.549

High

361362

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

605822

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.513

High

1101049

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1310450

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1439280

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.513

High

1448733

BABA1
BRISC and BRCA1-A complex member 1

1

0

High-throughput

0.513

High

831493

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

1448736

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

0

High-throughput

0.493

High

170375

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

953129

ACTB
Actin, cytoplasmic 1

1

2

High-throughput

0.479

High

294386

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

380160

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

641040

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

0

High-throughput

0.458

High

971146

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1026553

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1280536

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1289649

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1335521

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

0

High-throughput

0.458

High

1397467

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1435339

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1438354

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

1448275

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1448731

PHP14
14 kDa phosphohistidine phosphatase

1

0

High-throughput

0.458

High

1448734

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

1448735

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1234976

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.445

High

1448738

GAB2
GRB2-associated-binding protein 2

1

1

High-throughput

0.445

High

589798

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

1096828

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.437

High

404925

PRIO
Major prion protein

1

0

High-throughput

0.426

High

530428

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

728689

IL2RG
Cytokine receptor common subunit gamma

1

0

High-throughput

0.426

High

1209699

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1315555

ULK2
Serine/threonine-protein kinase ULK2

1

0

High-throughput

0.426

High

1447588

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.426

High

1448732

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.426

High

1448737

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

7

0

High-throughput

0.392

High

1417805

ANGL4
Angiopoietin-related protein 4

2

0

High-throughput

0.328

High

210126

CRX
Cone-rod homeobox protein

2

0

High-throughput

0.316

High

1206439

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

1358913

SEN15
tRNA-splicing endonuclease subunit Sen15

2

0

High-throughput

0.313

High

1407104

MDFI
MyoD family inhibitor

1

0

High-throughput

0.282

High

484659

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1200335

ANR39
Ankyrin repeat domain-containing protein 39

1

0

High-throughput

0.279

Low

1251690

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

1313089

T183A
Transmembrane protein 183A

1

0

High-throughput

0.279

Low

106705

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

254648

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

258343

TRI13
E3 ubiquitin-protein ligase TRIM13

1

0

High-throughput

0.249

Low

279512

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

316052

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

412668

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

696612

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769279

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

879502

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1135823

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

1255707

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1257142

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.249

Low

1288124

MARH3
E3 ubiquitin-protein ligase MARCHF3

1

0

High-throughput

0.249

Low

330333

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.232

Low

430406

JUN
Transcription factor Jun

1

0

High-throughput

0.232

Low

598783

ANFB
Natriuretic peptides B

1

0

High-throughput

0.232

Low

1104124

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

1314435

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025