Protein: SOST
Sclerostin

Gene: SOST
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q9BQB4

Gene Ontology (top 5):
GO:0001503 - ossification
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005794 - Golgi apparatus
GO:0008201 - heparin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

270322

LRP6
Low-density lipoprotein receptor-related protein 6

5

6

Small-scale

0.927

High

258340

LRP5
Low-density lipoprotein receptor-related protein 5

4

6

Small-scale

0.896

High

254290

LRP4
Low-density lipoprotein receptor-related protein 4

3

6

Small-scale

0.886

High

957637

LRP2
Low-density lipoprotein receptor-related protein 2

2

6

High-throughput

0.811

High

1269017

SORL
Sortilin-related receptor

1

5

High-throughput

0.691

High

214357

SPOP
Speckle-type POZ protein

2

0

High-throughput

0.602

High

483636

CSH2
Chorionic somatomammotropin hormone 2

2

0

High-throughput

0.602

High

596093

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

2

0

High-throughput

0.602

High

1289411

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

0

High-throughput

0.602

High

1309356

PSMG3
Proteasome assembly chaperone 3

2

0

High-throughput

0.602

High

1309357

SRRT
Serrate RNA effector molecule homolog

2

0

High-throughput

0.602

High

1293638

SAHH3
Adenosylhomocysteinase 3

2

1

High-throughput

0.574

High

1295342

DCAF5
DDB1- and CUL4-associated factor 5

2

1

High-throughput

0.574

High

310082

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

1

High-throughput

0.536

High

314778

PSMG1
Proteasome assembly chaperone 1

1

0

High-throughput

0.513

High

1309361

CRBG1
Beta/gamma crystallin domain-containing protein 1

1

0

High-throughput

0.513

High

1309362

UBP16
Ubiquitin carboxyl-terminal hydrolase 16

1

0

High-throughput

0.513

High

161439

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

2

High-throughput

0.489

High

216575

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

1

High-throughput

0.489

High

1309358

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

1

1

High-throughput

0.489

High

134957

IMA3
Importin subunit alpha-3

2

0

High-throughput

0.328

High

265010

MPPB
Mitochondrial-processing peptidase subunit beta

2

0

High-throughput

0.328

High

319989

HERC2
E3 ubiquitin-protein ligase HERC2

2

0

High-throughput

0.328

High

321625

AP2A1
AP-2 complex subunit alpha-1

2

0

High-throughput

0.328

High

615826

GCSP
Glycine dehydrogenase

2

0

High-throughput

0.328

High

942239

GTF2I
General transcription factor II-I

2

0

High-throughput

0.328

High

1282448

PSMG2
Proteasome assembly chaperone 2

2

0

High-throughput

0.328

High

1297013

ANM6
Protein arginine N-methyltransferase 6

2

0

High-throughput

0.328

High

1309359

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

2

0

High-throughput

0.328

High

1309360

PKHF2
Pleckstrin homology domain-containing family F member 2

2

0

High-throughput

0.316

High

382626

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

0

High-throughput

0.279

Low

1245032

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.279

Low

1261166

NUDT8
Mitochondrial coenzyme A diphosphatase NUDT8

1

0

High-throughput

0.279

Low

1295579

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024