Protein: TCHP
Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin) (Tumor suppressor protein)

Gene: TCHP
Organism: Homo sapiens
Interactions: 133
UniProt ID: Q9BT92

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1413290

NDK7
Nucleoside diphosphate kinase homolog 7

6

0

High-throughput

0.707

High

1033422

CDR2
Cerebellar degeneration-related protein 2

4

2

High-throughput

0.700

High

1413282

NDOR1
NADPH-dependent diflavin oxidoreductase 1

4

1

High-throughput

0.698

High

618097

K1C15
Keratin, type I cytoskeletal 15

3

20

High-throughput

0.676

High

505678

CC172
Coiled-coil domain-containing protein 172

4

0

High-throughput

0.668

High

787580

TNR3
Tumor necrosis factor receptor superfamily member 3

3

4

High-throughput

0.667

High

476380

K1C16
Keratin, type I cytoskeletal 16

3

20

Small-scale

0.663

High

578708

GLNA
Glutamine synthetase

4

0

High-throughput

0.661

High

475678

K1C19
Keratin, type I cytoskeletal 19

3

20

High-throughput

0.653

High

1093703

MKRN3
E3 ubiquitin-protein ligase makorin-3

4

1

High-throughput

0.637

High

1411264

LZTS2
Leucine zipper putative tumor suppressor 2

2

19

High-throughput

0.631

High

572173

TRI27
Zinc finger protein RFP

2

7

High-throughput

0.628

High

1178004

MOONR
Protein moonraker

3

0

High-throughput

0.625

High

1314941

CCD13
Coiled-coil domain-containing protein 13

2

18

High-throughput

0.615

High

474940

VIME
Vimentin

2

20

High-throughput

0.614

High

436991

K1C18
Keratin, type I cytoskeletal 18

2

20

Small-scale

0.606

High

437324

K2C8
Keratin, type II cytoskeletal 8

2

11

Small-scale

0.606

High

300482

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.606

High

341844

K2C75
Keratin, type II cytoskeletal 75

2

9

High-throughput

0.606

High

701217

PSB5
Proteasome subunit beta type-5

2

1

High-throughput

0.606

High

1127796

K1H2
Keratin, type I cuticular Ha2

2

20

High-throughput

0.606

High

1178750

K1C24
Keratin, type I cytoskeletal 24

2

17

High-throughput

0.606

High

1205965

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

19

High-throughput

0.606

High

1276151

NUP54
Nucleoporin p54

2

3

High-throughput

0.606

High

1293016

CDR2L
Cerebellar degeneration-related protein 2-like

2

2

High-throughput

0.606

High

1367977

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.606

High

1388847

HOOK2
Protein Hook homolog 2

2

18

High-throughput

0.606

High

1413265

TRI54
Tripartite motif-containing protein 54

2

18

High-throughput

0.606

High

1413274

4ET
Eukaryotic translation initiation factor 4E transporter

2

2

High-throughput

0.606

High

1413278

WWOX
WW domain-containing oxidoreductase

2

1

High-throughput

0.606

High

1413284

RABX5
Rab5 GDP/GTP exchange factor

2

6

High-throughput

0.606

High

1413285

IKZF3
Zinc finger protein Aiolos

2

2

High-throughput

0.606

High

326609

MFN2
Mitofusin-2

2

2

Small-scale

0.584

High

1143502

PCM1
Pericentriolar material 1 protein

2

1

High-throughput

0.584

High

1226252

CP135
Centrosomal protein of 135 kDa

2

16

High-throughput

0.584

High

298068

SPF27
Pre-mRNA-splicing factor SPF27

2

0

High-throughput

0.580

High

1036545

ID2
DNA-binding protein inhibitor ID-2

2

0

High-throughput

0.580

High

1295770

CC125
Coiled-coil domain-containing protein 125

2

0

High-throughput

0.580

High

1328060

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

2

0

High-throughput

0.580

High

1413264

RUSC1
AP-4 complex accessory subunit RUSC1

2

0

High-throughput

0.580

High

1413272

DMAP1
DNA methyltransferase 1-associated protein 1

2

0

High-throughput

0.580

High

1230231

K1C40
Keratin, type I cytoskeletal 40

1

20

High-throughput

0.573

High

1398346

CEP63
Centrosomal protein of 63 kDa

2

19

High-throughput

0.571

High

1149364

STIL
SCL-interrupting locus protein

2

0

High-throughput

0.559

High

1330070

USBP1
Harmonin-binding protein USHBP1

2

13

High-throughput

0.553

High

1332427

CBY2
Protein chibby homolog 2

2

1

High-throughput

0.553

High

1413279

ZIM2
Zinc finger imprinted 2

2

1

High-throughput

0.553

High

1154578

CC85B
Coiled-coil domain-containing protein 85B

1

1

High-throughput

0.541

High

1314990

TEX11
Testis-expressed protein 11

1

1

High-throughput

0.541

High

1328663

KCD17
BTB/POZ domain-containing protein KCTD17

1

13

Small-scale

0.536

High

682593

S100P
Protein S100-P

1

3

High-throughput

0.536

High

1115035

CUL4A
Cullin-4A

1

9

High-throughput

0.536

High

385161

K1C14
Keratin, type I cytoskeletal 14

1

20

Small-scale

0.527

High

385318

K2C6A
Keratin, type II cytoskeletal 6A

1

11

Small-scale

0.527

High

566441

K2C5
Keratin, type II cytoskeletal 5

1

10

Small-scale

0.527

High

1413263

BEGIN
Brain-enriched guanylate kinase-associated protein

1

0

High-throughput

0.493

High

1322283

SPG16
Sperm-associated antigen 16 protein

1

7

High-throughput

0.489

High

1413268

PRD16
Histone-lysine N-methyltransferase PRDM16

1

4

High-throughput

0.481

High

164074

NDC80
Kinetochore protein NDC80 homolog

1

17

High-throughput

0.479

High

177054

CE290
Centrosomal protein of 290 kDa

1

20

High-throughput

0.479

High

242760

PRKN
E3 ubiquitin-protein ligase parkin

1

10

Small-scale

0.479

High

291516

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.479

High

324207

CE152
Centrosomal protein of 152 kDa

1

13

High-throughput

0.479

High

340227

PCNT
Pericentrin

1

19

High-throughput

0.479

High

341664

EYA4
Protein phosphatase EYA4

1

3

High-throughput

0.479

High

349224

LATS1
Serine/threonine-protein kinase LATS1

1

10

High-throughput

0.479

High

414523

P53
Cellular tumor antigen p53

1

5

High-throughput

0.479

High

457658

TBB5
Tubulin beta chain

1

6

High-throughput

0.479

High

570577

GFAP
Glial fibrillary acidic protein

1

20

High-throughput

0.479

High

655910

TBG1
Tubulin gamma-1 chain

1

11

High-throughput

0.479

High

721060

CLIP1
CAP-Gly domain-containing linker protein 1

1

19

High-throughput

0.479

High

833353

PERI
Peripherin

1

20

High-throughput

0.479

High

936437

AFAD
Afadin

1

15

High-throughput

0.479

High

953064

ACTB
Actin, cytoplasmic 1

1

18

High-throughput

0.479

High

1051045

FAK1
Focal adhesion kinase 1

1

18

High-throughput

0.479

High

1065759

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

10

High-throughput

0.479

High

1110709

DCTN2
Dynactin subunit 2

1

1

High-throughput

0.479

High

1156585

CCDC6
Coiled-coil domain-containing protein 6

1

18

High-throughput

0.479

High

1165496

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

2

High-throughput

0.479

High

1197073

AMOT
Angiomotin

1

17

High-throughput

0.479

High

1203245

ODFP2
Outer dense fiber protein 2

1

13

High-throughput

0.479

High

1210974

CE170
Centrosomal protein of 170 kDa

1

8

High-throughput

0.479

High

1215505

CE162
Centrosomal protein of 162 kDa

1

19

High-throughput

0.479

High

1227370

A16L1
Autophagy-related protein 16-1

1

15

High-throughput

0.479

High

1228469

FTM
Protein fantom

1

19

High-throughput

0.479

High

1248189

SAS6
Spindle assembly abnormal protein 6 homolog

1

15

High-throughput

0.479

High

1252208

SYNE3
Nesprin-3

1

18

High-throughput

0.479

High

1256578

CE128
Centrosomal protein of 128 kDa

1

19

High-throughput

0.479

High

1280913

CNTRL
Centriolin

1

15

High-throughput

0.479

High

1291353

LCA5
Lebercilin

1

19

High-throughput

0.479

High

1295545

MIB1
E3 ubiquitin-protein ligase MIB1

1

6

High-throughput

0.479

High

1322441

SPICE
Spindle and centriole-associated protein 1

1

1

High-throughput

0.479

High

1322784

CNTRB
Centrobin

1

18

High-throughput

0.479

High

1326328

NIN
Ninein

1

19

High-throughput

0.479

High

1333014

F184A
Protein FAM184A

1

15

High-throughput

0.479

High

1334165

POC1A
POC1 centriolar protein homolog A

1

10

High-throughput

0.479

High

1336829

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

12

High-throughput

0.479

High

1353256

PARD3
Partitioning defective 3 homolog

1

7

High-throughput

0.479

High

1368942

GOGA1
Golgin subfamily A member 1

1

14

High-throughput

0.479

High

1403069

CEP89
Centrosomal protein of 89 kDa

1

18

High-throughput

0.479

High

1413269

CPAP
Centrosomal P4.1-associated protein

1

15

High-throughput

0.479

High

1413270

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

16

High-throughput

0.479

High

1413275

LATS2
Serine/threonine-protein kinase LATS2

1

10

High-throughput

0.479

High

1413281

ZO2
Tight junction protein 2

1

5

High-throughput

0.479

High

1413283

XPO7
Exportin-7

1

1

High-throughput

0.479

High

1413286

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

9

High-throughput

0.479

High

1413287

FBW1A
F-box/WD repeat-containing protein 1A

1

7

High-throughput

0.479

High

1413288

ADIP
Afadin- and alpha-actinin-binding protein

1

1

High-throughput

0.479

High

1413289

NINL
Ninein-like protein

1

19

High-throughput

0.479

High

1413271

HM20A
High mobility group protein 20A

1

4

High-throughput

0.470

High

176535

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.458

High

245361

CE104
Centrosomal protein of 104 kDa

1

0

High-throughput

0.458

High

290133

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

688304

TTP
mRNA decay activator protein ZFP36

1

0

High-throughput

0.458

High

895019

EMD
Emerin

1

0

High-throughput

0.458

High

1030330

AMPD2
AMP deaminase 2

1

0

High-throughput

0.458

High

1193474

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.458

High

1413266

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1395392

NEUL4
Neuralized-like protein 4

1

2

High-throughput

0.445

High

1068856

IFFO1
Non-homologous end joining factor IFFO1

1

13

High-throughput

0.439

High

106574

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

1241944

FBX42
F-box only protein 42

1

3

High-throughput

0.437

High

1258073

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

1

1

Small-scale

0.437

High

1383663

VP33A
Vacuolar protein sorting-associated protein 33A

1

2

High-throughput

0.437

High

1413273

MED4
Mediator of RNA polymerase II transcription subunit 4

1

3

High-throughput

0.437

High

1413276

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

1

High-throughput

0.437

High

1152949

NAB2
NGFI-A-binding protein 2

4

0

High-throughput

0.364

High

1359110

DYDC1
DPY30 domain-containing protein 1

3

0

High-throughput

0.352

High

1207686

MIIP
Migration and invasion-inhibitory protein

2

0

High-throughput

0.316

High

1413277

EURL
Protein EURL homolog

2

0

High-throughput

0.316

High

1350351

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.299

High

1413267

STN1
CST complex subunit STN1

1

0

High-throughput

0.268

Low

1413280

ZMAT5
Zinc finger matrin-type protein 5

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025