Protein: PRP18
Pre-mRNA-splicing factor 18 (PRP18 homolog) (hPRP18)

Gene: PRP18, PRPF18
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q99633

Gene Ontology (top 5):
GO:0000350 - generation of catalytic spliceosome for second transesterification step
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
GO:0005682 - U5 snRNP

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

216282

PPIH
Peptidyl-prolyl cis-trans isomerase H

2

1

High-throughput

0.783

High

1406158

ZRAN1
Ubiquitin thioesterase ZRANB1

3

0

High-throughput

0.625

High

51485

FSD2
Fibronectin type III and SPRY domain-containing protein 2

2

2

High-throughput

0.606

High

1104655

IKZF1
DNA-binding protein Ikaros

2

1

High-throughput

0.606

High

1401277

NACC1
Nucleus accumbens-associated protein 1

2

1

High-throughput

0.606

High

269357

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

303343

PDE9A
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

2

0

High-throughput

0.580

High

343794

LDOC1
Protein LDOC1

2

0

High-throughput

0.580

High

572159

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.580

High

659571

CRCM
Colorectal mutant cancer protein

2

0

High-throughput

0.580

High

666895

CCNC
Cyclin-C

2

0

High-throughput

0.580

High

783387

TRI23
E3 ubiquitin-protein ligase TRIM23

2

0

High-throughput

0.580

High

1090876

TRAF2
TNF receptor-associated factor 2

2

0

High-throughput

0.580

High

1095769

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

2

0

High-throughput

0.580

High

1196306

GRAP1
GRIP1-associated protein 1

2

0

High-throughput

0.580

High

1205955

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

0

High-throughput

0.580

High

1238107

HMBX1
Homeobox-containing protein 1

2

0

High-throughput

0.580

High

1279715

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

2

0

High-throughput

0.580

High

1292616

GPBP1
Vasculin

2

0

High-throughput

0.580

High

1353588

ZN526
Zinc finger protein 526

2

0

High-throughput

0.580

High

1402363

CSRN1
Cysteine/serine-rich nuclear protein 1

2

0

High-throughput

0.580

High

1404643

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.580

High

1405602

TSNAX
Translin-associated protein X

2

0

High-throughput

0.580

High

1406145

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

1406152

ASCC2
Activating signal cointegrator 1 complex subunit 2

2

0

High-throughput

0.580

High

1406154

GO45
Golgin-45

2

0

High-throughput

0.580

High

1406161

ZN639
Zinc finger protein 639

2

0

High-throughput

0.580

High

1406168

NEMO
NF-kappa-B essential modulator

2

0

High-throughput

0.580

High

65144

GG6L9
Golgin subfamily A member 6-like protein 9

2

1

High-throughput

0.553

High

300473

KRT34
Keratin, type I cuticular Ha4

2

4

High-throughput

0.553

High

1063564

GOGA2
Golgin subfamily A member 2

2

1

High-throughput

0.553

High

1146115

K1H1
Keratin, type I cuticular Ha1

2

4

High-throughput

0.553

High

1230221

K1C40
Keratin, type I cytoskeletal 40

2

4

High-throughput

0.553

High

1230340

K1C39
Keratin, type I cytoskeletal 39

2

4

High-throughput

0.553

High

1367975

KRT35
Keratin, type I cuticular Ha5

2

4

High-throughput

0.553

High

1406146

LZTS2
Leucine zipper putative tumor suppressor 2

2

1

High-throughput

0.553

High

1406150

CAR10
Caspase recruitment domain-containing protein 10

2

1

High-throughput

0.553

High

1406151

TRI54
Tripartite motif-containing protein 54

2

2

High-throughput

0.553

High

1406153

CARD9
Caspase recruitment domain-containing protein 9

2

1

High-throughput

0.553

High

1406165

LZTS1
Leucine zipper putative tumor suppressor 1

2

1

High-throughput

0.553

High

1232537

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

1406162

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.515

High

990652

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.513

High

185230

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.493

High

900115

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.493

High

1394255

GMCL1
Germ cell-less protein-like 1

1

0

High-throughput

0.493

High

1406159

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.493

High

894113

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

1294624

NUTM1
NUT family member 1

1

2

High-throughput

0.481

High

1361143

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.481

High

1145514

RBBP5
Retinoblastoma-binding protein 5

1

1

High-throughput

0.479

High

1406160

XPO7
Exportin-7

1

1

High-throughput

0.479

High

1406164

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

60252

A2RRN7
CADPS protein

1

1

High-throughput

0.470

High

85458

B7ZLH0
FAM22F protein

1

2

High-throughput

0.470

High

1194573

Q4G0R1
PIBF1 protein

1

1

High-throughput

0.470

High

1311771

HOMEZ
Homeobox and leucine zipper protein Homez

1

0

High-throughput

0.460

High

1406157

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.460

High

714379

PML
Protein PML

1

0

High-throughput

0.458

High

887160

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

1387518

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

1406149

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

51331

NTM2F
NUT family member 2F

1

2

High-throughput

0.439

High

1406163

CAPS1
Calcium-dependent secretion activator 1

1

1

High-throughput

0.439

High

286714

STX11
Syntaxin-11

2

0

High-throughput

0.316

High

353737

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.316

High

725447

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

0

High-throughput

0.316

High

1033416

CDR2
Cerebellar degeneration-related protein 2

2

0

High-throughput

0.316

High

1179936

TXIP1
Translin-associated factor X-interacting protein 1

2

0

High-throughput

0.316

High

1180015

CCD57
Coiled-coil domain-containing protein 57

2

0

High-throughput

0.316

High

1201878

PKHG4
Puratrophin-1

2

0

High-throughput

0.316

High

1206425

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

1211757

UBX11
UBX domain-containing protein 11

2

0

High-throughput

0.316

High

1225055

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

0

High-throughput

0.316

High

1228706

C102B
Coiled-coil domain-containing protein 102B

2

0

High-throughput

0.316

High

1238585

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.316

High

1247401

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.316

High

1279969

NECA2
N-terminal EF-hand calcium-binding protein 2

2

0

High-throughput

0.316

High

1289394

URP2
Fermitin family homolog 3

2

0

High-throughput

0.316

High

1332424

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.316

High

1336142

CC150
Coiled-coil domain-containing protein 150

2

0

High-throughput

0.316

High

1336452

PNMA1
Paraneoplastic antigen Ma1

2

0

High-throughput

0.316

High

1340327

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.316

High

1350424

BICD2
Protein bicaudal D homolog 2

2

0

High-throughput

0.316

High

1371417

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

0

High-throughput

0.316

High

1386101

EVI5L
EVI5-like protein

2

0

High-throughput

0.316

High

1386135

GCC1
GRIP and coiled-coil domain-containing protein 1

2

0

High-throughput

0.316

High

1386678

AP2M1
AP-2 complex subunit mu

2

0

High-throughput

0.316

High

1388841

HOOK2
Protein Hook homolog 2

2

0

High-throughput

0.316

High

1398284

KCTD7
BTB/POZ domain-containing protein KCTD7

2

0

High-throughput

0.316

High

1406147

BEGIN
Brain-enriched guanylate kinase-associated protein

2

0

High-throughput

0.316

High

1406148

KIFC3
Kinesin-like protein KIFC3

2

0

High-throughput

0.316

High

1406155

OSBL3
Oxysterol-binding protein-related protein 3

2

0

High-throughput

0.316

High

1406156

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1406167

AMOL2
Angiomotin-like protein 2

2

0

High-throughput

0.316

High

353523

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.268

Low

516780

SCHI1
Schwannomin-interacting protein 1

1

0

High-throughput

0.268

Low

1220036

TTC23
Tetratricopeptide repeat protein 23

1

0

High-throughput

0.268

Low

1245610

TXD11
Thioredoxin domain-containing protein 11

1

0

High-throughput

0.268

Low

1386865

DDT4L
DNA damage-inducible transcript 4-like protein

1

0

High-throughput

0.268

Low

1270959

RHOU
Rho-related GTP-binding protein RhoU

1

0

High-throughput

0.261

Low

1395331

CC136
Coiled-coil domain-containing protein 136

1

0

High-throughput

0.251

Low

1406166

NINL
Ninein-like protein

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025