Protein: NEUR1
Sialidase-1 (EC 3.2.1.18) (Acetylneuraminyl hydrolase) (G9 sialidase) (Lysosomal sialidase) (N-acetyl-alpha-neuraminidase 1)

Gene: NEUR1, NEU1
Organism: Homo sapiens
Interactions: 70
UniProt ID: Q99519

Gene Ontology (top 5):
GO:0004308 - exo-alpha-sialidase activity
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1351687

GP152
Probable G-protein coupled receptor 152

2

2

High-throughput

0.783

High

907108

CCR9
C-C chemokine receptor type 9

1

1

High-throughput

0.698

High

597008

TSHR
Thyrotropin receptor

1

0

High-throughput

0.656

High

1134153

NTCP
Hepatic sodium/bile acid cotransporter

2

1

High-throughput

0.606

High

1186027

SOAT
Sodium-dependent organic anion transporter

2

1

High-throughput

0.606

High

1384337

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

2

High-throughput

0.606

High

166987

MGST3
Glutathione S-transferase 3, mitochondrial

2

0

High-throughput

0.580

High

549866

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.580

High

590335

MUC1
Mucin-1

2

0

High-throughput

0.580

High

1333482

GOLM1
Golgi membrane protein 1

2

0

High-throughput

0.580

High

1333968

DHB11
Estradiol 17-beta-dehydrogenase 11

2

0

High-throughput

0.580

High

1352503

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.580

High

1405031

S39A9
Zinc transporter ZIP9

2

0

High-throughput

0.580

High

1405037

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

230405

CREB3
Cyclic AMP-responsive element-binding protein 3

1

2

High-throughput

0.573

High

1306981

CERS3
Ceramide synthase 3

2

1

High-throughput

0.553

High

1405026

CERS4
Ceramide synthase 4

2

1

High-throughput

0.553

High

231337

EFNA2
Ephrin-A2

1

1

High-throughput

0.536

High

342649

LY86
Lymphocyte antigen 86

1

1

High-throughput

0.536

High

841575

I12R1
Interleukin-12 receptor subunit beta-1

1

2

High-throughput

0.536

High

1405022

TBB2B
Tubulin beta-2B chain

1

1

High-throughput

0.536

High

892719

DNLI4
DNA ligase 4

1

0

High-throughput

0.529

High

996303

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.518

High

65952

LIRA5
Leukocyte immunoglobulin-like receptor subfamily A member 5

1

0

High-throughput

0.513

High

143757

WN10B
Protein Wnt-10b

1

0

High-throughput

0.513

High

561385

TDGF1
Protein Cripto

1

0

High-throughput

0.513

High

1199823

AGK
Acylglycerol kinase, mitochondrial

1

0

High-throughput

0.513

High

1405024

CST11
Cystatin-11

1

0

High-throughput

0.513

High

1405032

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

595100

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

1

Small-scale

0.501

High

648793

KCNA4
Potassium voltage-gated channel subfamily A member 4

1

1

Small-scale

0.501

High

1157040

NTRK3
NT-3 growth factor receptor

1

1

High-throughput

0.500

High

1405035

ERRFI
ERBB receptor feedback inhibitor 1

1

1

Small-scale

0.481

High

508493

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

593694

BGAL
Beta-galactosidase

1

0

Small-scale

0.480

High

1055082

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

0

High-throughput

0.479

High

126331

TLR4
Toll-like receptor 4

1

3

Small-scale

0.479

High

188974

TMPS2
Transmembrane protease serine 2

1

1

High-throughput

0.479

High

191234

TLR3
Toll-like receptor 3

1

3

Small-scale

0.479

High

218667

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

252367

TLR2
Toll-like receptor 2

1

3

Small-scale

0.479

High

294223

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

528710

PPGB
Lysosomal protective protein

1

1

Small-scale

0.479

High

1405025

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

1

High-throughput

0.479

High

1405029

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.479

High

1405034

XPO7
Exportin-7

1

1

High-throughput

0.479

High

242689

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

363756

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

401351

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

1024790

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1255204

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1397339

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1405027

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1405033

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1405036

HDAC5
Histone deacetylase 5

1

0

High-throughput

0.458

High

372936

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

406545

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

756581

GALNS
N-acetylgalactosamine-6-sulfatase

1

0

Small-scale

0.426

High

876437

EAA4
Excitatory amino acid transporter 4

1

0

High-throughput

0.426

High

935786

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.426

High

926828

VMAT1
Chromaffin granule amine transporter

2

0

High-throughput

0.316

High

1109024

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

1142925

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.316

High

1405030

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

603682

JUNB
Transcription factor JunB

1

0

High-throughput

0.282

High

956101

SPCS3
Signal peptidase complex subunit 3

1

0

High-throughput

0.279

Low

1405023

COMD5
COMM domain-containing protein 5

1

0

High-throughput

0.279

Low

386138

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

1368576

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.249

Low

1405028

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025