Protein: PP2C3
Protein phosphatase 2C homolog 3 (PP2C-3) (EC 3.1.3.16)

Gene: PP2C3, PTC3
Organism: Saccharomyces cerevisiae S288C
Interactions: 60
UniProt ID: P34221

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007165 - signal transduction
GO:0010508 - positive regulation of autophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

709346

HRR25
Casein kinase I homolog HRR25

2

16

High-throughput

0.759

High

757852

PAA1
Polyamine N-acetyltransferase 1

9

2

Small-scale

0.757

High

646650

VPS15
Serine/threonine-protein kinase VPS15

2

20

High-throughput

0.717

High

757837

TDA10
Probable ATP-dependent kinase TDA10

3

0

High-throughput

0.641

High

555246

RAD50
DNA repair protein RAD50

2

0

High-throughput

0.595

High

598842

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

2

0

High-throughput

0.563

High

757831

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.563

High

757847

TSR1
Ribosome biogenesis protein TSR1

2

0

High-throughput

0.563

High

544365

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.552

High

434981

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.547

High

757832

ECM29
Proteasome component ECM29

1

4

High-throughput

0.536

High

757854

TCB1
Tricalbin-1

1

4

High-throughput

0.536

High

757840

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.513

High

757850

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.513

High

675877

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.500

High

649810

VPS34
Phosphatidylinositol 3-kinase VPS34

1

0

High-throughput

0.493

High

757842

COPA
Coatomer subunit alpha

1

2

High-throughput

0.489

High

757844

ACAC
Acetyl-CoA carboxylase

1

2

Small-scale

0.481

High

397493

REP1
Partitioning protein REP1

1

0

High-throughput

0.479

High

645356

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.479

High

149682

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

392510

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.479

High

579144

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

706695

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

757838

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

757843

HST2
NAD-dependent protein deacetylase HST2

1

1

High-throughput

0.479

High

757845

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

757846

ATG13
Autophagy-related protein 13

1

1

Small-scale

0.479

High

757848

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

757853

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

603036

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

647076

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

745693

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

757829

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

757839

MAD3
Spindle assembly checkpoint component MAD3

1

0

Small-scale

0.458

High

757833

CH10
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.457

High

366993

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.457

High

425120

OTC
Ornithine carbamoyltransferase

1

2

High-throughput

0.457

High

661605

MPCP
Mitochondrial phosphate carrier protein

1

2

High-throughput

0.457

High

394421

EF1A
Elongation factor 1-alpha

1

4

High-throughput

0.445

High

453526

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

523528

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

526328

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

757835

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

757836

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.445

High

682228

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.437

High

757851

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.437

High

734059

EF2
Elongation factor 2

1

1

High-throughput

0.407

High

747274

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.407

High

672295

RV161
Reduced viability upon starvation protein 161

1

0

High-throughput

0.279

Low

757830

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

757834

RAD55
DNA repair protein RAD55

1

0

High-throughput

0.279

Low

405072

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

619347

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.261

Low

673491

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.261

Low

441824

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

502958

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

757841

YPT32
GTP-binding protein YPT32/YPT11

1

0

High-throughput

0.249

Low

757849

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

689365

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025