Protein: KIN2
Serine/threonine-protein kinase KIN2 (EC 2.7.11.1)

Gene: KIN2
Organism: Saccharomyces cerevisiae S288C
Interactions: 165
UniProt ID: P13186

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

364287

CDK1
Cyclin-dependent kinase 1

2

2

High-throughput

0.825

High

560752

SLT2
Mitogen-activated protein kinase SLT2/MPK1

2

3

High-throughput

0.811

High

560743

CBK1
Serine/threonine-protein kinase CBK1

2

15

High-throughput

0.808

High

560654

BUD14
Bud site selection protein 14

4

2

High-throughput

0.702

High

560733

KEL2
Kelch repeat-containing protein 2

4

6

High-throughput

0.697

High

488909

SWI6
Regulatory protein SWI6

1

5

High-throughput

0.691

High

560643

GCN2
eIF-2-alpha kinase GCN2

1

16

High-throughput

0.691

High

560647

CSK22
Casein kinase II subunit alpha'

1

7

High-throughput

0.691

High

560650

MPIP
M-phase inducer phosphatase

1

2

High-throughput

0.691

High

560668

ELM1
Serine/threonine-protein kinase ELM1

1

17

High-throughput

0.691

High

560670

SWE1
Mitosis inhibitor protein kinase SWE1

1

20

High-throughput

0.691

High

560678

KDX1
Serine/threonine-protein kinase KDX1

1

2

High-throughput

0.691

High

560684

BOI1
BEM1-interacting protein 1

1

1

High-throughput

0.691

High

560689

KSP1
Serine/threonine-protein kinase KSP1

1

17

High-throughput

0.691

High

560720

RIM15
Serine/threonine-protein kinase RIM15

1

20

High-throughput

0.691

High

560751

CDC14
Tyrosine-protein phosphatase CDC14

1

6

High-throughput

0.691

High

560695

KEL1
Kelch repeat-containing protein 1

3

6

High-throughput

0.669

High

560750

RHO3
GTP-binding protein RHO3

1

20

Small-scale

0.665

High

560655

MIG1
Regulatory protein MIG1

1

4

High-throughput

0.647

High

560734

YPT32
GTP-binding protein YPT32/YPT11

1

5

High-throughput

0.647

High

560747

CRZ1
Transcriptional regulator CRZ1

1

2

High-throughput

0.647

High

560748

ACT
Actin

1

3

High-throughput

0.646

High

560711

SEC9
Protein transport protein SEC9

2

1

Small-scale

0.629

High

560759

GIS4
Protein GIS4

2

2

High-throughput

0.628

High

560639

CG13
G1/S-specific cyclin CLN3

1

1

High-throughput

0.621

High

560754

KIN4
Serine/threonine-protein kinase KIN4

1

16

High-throughput

0.618

High

560773

SRO7
Lethal(2) giant larvae protein homolog SRO7

1

1

Small-scale

0.618

High

560726

BUD4
Bud site selection protein 4

1

0

High-throughput

0.614

High

560676

ATG19
Autophagy-related protein 19

2

3

High-throughput

0.602

High

560707

SHO1
High osmolarity signaling protein SHO1

2

0

High-throughput

0.594

High

560657

BMH1
Protein BMH1

2

20

Small-scale

0.586

High

560662

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

4

High-throughput

0.575

High

560741

JJJ1
J protein JJJ1

1

6

High-throughput

0.575

High

522893

HSP71
Heat shock protein SSA1

2

10

High-throughput

0.571

High

560779

HSP42
Heat shock protein 42

2

0

High-throughput

0.559

High

560642

SEC23
Protein transport protein SEC23

2

1

High-throughput

0.558

High

543641

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.536

High

560640

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

6

High-throughput

0.536

High

560659

XPO1
Exportin-1

1

6

High-throughput

0.536

High

560660

HS104
Heat shock protein 104

1

3

High-throughput

0.536

High

560666

PP12
Serine/threonine-protein phosphatase PP1-2

1

7

High-throughput

0.536

High

560671

BCK2
Protein BCK2

1

1

High-throughput

0.536

High

560679

EF1G2
Elongation factor 1-gamma 2

1

2

High-throughput

0.536

High

560696

KOG1
Target of rapamycin complex 1 subunit KOG1

1

8

High-throughput

0.536

High

560700

YM11
Uncharacterized protein YMR124W

1

1

High-throughput

0.536

High

560719

MOB2
CBK1 kinase activator protein MOB2

1

1

High-throughput

0.536

High

560729

ASK10
Activator of SKN7 protein 10

1

4

High-throughput

0.536

High

560766

RGC1
Regulator of the glycerol channel 1

1

4

High-throughput

0.536

High

433406

RL26A
Large ribosomal subunit protein uL24A

2

2

High-throughput

0.533

High

560649

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.513

High

560663

KRE6
Beta-glucan synthesis-associated protein KRE6

1

0

High-throughput

0.513

High

560673

TFC4
Transcription factor tau 131 kDa subunit

1

0

High-throughput

0.513

High

560685

SEA4
SEH-associated protein 4

1

0

High-throughput

0.513

High

560687

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.513

High

560699

POP2
Poly(A) ribonuclease POP2

1

0

High-throughput

0.513

High

560705

ZRG8
Zinc-regulated protein 8

1

0

High-throughput

0.513

High

560757

YD239
Uncharacterized protein YDR239C

1

0

High-throughput

0.513

High

560776

CRM2
Homeostatic regulator of DAG

1

0

High-throughput

0.513

High

560658

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.508

High

452772

IPMK
Inositol polyphosphate multikinase

1

1

High-throughput

0.501

High

511051

MALX2
Oligo-1,6-glucosidase IMA3

1

2

High-throughput

0.501

High

560664

HSP7F
Heat shock protein homolog SSE1

1

16

High-throughput

0.501

High

560665

HSP79
Heat shock protein homolog SSE2

1

16

High-throughput

0.501

High

560680

PXL1
Paxillin-like protein 1

1

4

High-throughput

0.501

High

560697

SET5
Histone-lysine N-methyltransferase SET5

1

2

High-throughput

0.501

High

560715

AGE2
ADP-ribosylation factor GTPase-activating protein effector protein 2

1

4

High-throughput

0.501

High

560718

BNI1
Protein BNI1

1

2

High-throughput

0.501

High

560723

CYP7
Peptidyl-prolyl cis-trans isomerase CYP7

1

2

High-throughput

0.501

High

560731

PALH
pH-response regulator protein palH/RIM21

1

1

Small-scale

0.501

High

560738

EFM5
Protein-lysine N-methyltransferase EFM5

1

1

High-throughput

0.501

High

560762

GSF2
Glucose-signaling factor 2

1

1

High-throughput

0.501

High

560767

YL345
Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W [Includes: 6-phosphofructo-2-kinase

1

4

High-throughput

0.501

High

560645

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

4

High-throughput

0.500

High

560646

METK2
S-adenosylmethionine synthase 2

1

1

High-throughput

0.500

High

560749

PEX13
Peroxisomal membrane protein PEX13

1

1

High-throughput

0.494

High

560702

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.493

High

560708

PEA2
Protein PEA2

1

0

Small-scale

0.493

High

560722

NET1
Nucleolar protein NET1

1

1

High-throughput

0.489

High

560727

IML1
Vacuolar membrane-associated protein IML1

1

5

High-throughput

0.489

High

560736

SEH1
Nucleoporin SEH1

1

3

High-throughput

0.489

High

560745

SFB2
SED5-binding protein 2

1

1

High-throughput

0.489

High

560758

WDR59
Maintenance of telomere capping protein 5

1

7

High-throughput

0.489

High

560771

RTC1
Restriction of telomere capping protein 1

1

7

High-throughput

0.489

High

560774

PSH1
RING finger protein PSH1

1

3

High-throughput

0.489

High

560778

ATG34
Autophagy-related protein 34

1

3

High-throughput

0.489

High

560661

CDC11
Cell division control protein 11

1

1

Small-scale

0.481

High

464306

OAT
Ornithine aminotransferase

1

0

High-throughput

0.480

High

560653

PUR7
Phosphoribosylaminoimidazole-succinocarboxamide synthase

1

0

High-throughput

0.480

High

560672

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.480

High

560681

SKG1
Suppressor of lethality of KEX2 GAS1 double null mutant protein 1

1

0

High-throughput

0.480

High

560682

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.480

High

560686

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

0

High-throughput

0.480

High

560693

FSH1
Family of serine hydrolases 1

1

0

High-throughput

0.480

High

560706

YEQ9
Uncharacterized protein YER079W

1

0

High-throughput

0.480

High

560713

VHS2
Protein VHS2

1

0

High-throughput

0.480

High

560725

YJ26
Uncharacterized protein YJR056C

1

0

High-throughput

0.480

High

560744

VAC7
Vacuolar segregation protein 7

1

0

High-throughput

0.480

High

560760

YM54
Uncharacterized protein YMR196W

1

0

High-throughput

0.480

High

560768

YL257
Uncharacterized protein YLR257W

1

0

High-throughput

0.480

High

560780

PAA1
Polyamine N-acetyltransferase 1

1

0

High-throughput

0.480

High

149547

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

434768

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

435730

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

514414

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

560651

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

560677

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

560683

GBLP
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.479

High

560690

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

560710

RIO2
Serine/threonine-protein kinase RIO2

1

3

High-throughput

0.479

High

560753

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

560764

PAL1
Protein PAL1

1

1

High-throughput

0.479

High

560775

RIO1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

560667

PMD1
Negative regulator of sporulation PMD1

1

0

High-throughput

0.458

High

560732

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

560746

BOP3
Protein BOP3

1

0

High-throughput

0.458

High

460706

CDC4
Cell division control protein 4

1

5

Small-scale

0.457

High

560644

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.457

High

560688

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

3

High-throughput

0.457

High

560721

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

18

High-throughput

0.457

High

560728

CTH1
mRNA decay factor CTH1

1

2

High-throughput

0.457

High

560737

MALX3
Oligo-1,6-glucosidase IMA1

1

2

High-throughput

0.457

High

560740

YN93
Uncharacterized hydrolase YNR064C

1

1

High-throughput

0.457

High

560742

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

14

High-throughput

0.457

High

560765

STP3
Zinc finger protein STP3

1

1

High-throughput

0.457

High

560770

ACK1
Activator of C kinase protein 1

1

1

High-throughput

0.457

High

560777

CRC1
Mitochondrial carnitine carrier

1

4

High-throughput

0.457

High

481451

HSP73
Heat shock protein SSA3

1

10

High-throughput

0.445

High

525782

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

560641

CYPH
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.445

High

560694

SSZ1
Ribosome-associated complex subunit SSZ1

1

7

High-throughput

0.445

High

560698

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

2

High-throughput

0.445

High

560704

HSP7E
Heat shock protein SSC3, mitochondrial

1

9

High-throughput

0.445

High

560709

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

560712

6P21
6-phosphofructo-2-kinase 1

1

4

High-throughput

0.445

High

409898

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

441662

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

502804

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

512218

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

512777

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

560656

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

560669

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

560674

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

560701

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

560755

MLP1
Protein MLP1

1

4

High-throughput

0.437

High

560772

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

560730

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.426

High

560735

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

560761

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.426

High

560717

SA185
SIT4-associating protein SAP185

1

4

High-throughput

0.407

High

560769

BRE1
E3 ubiquitin-protein ligase BRE1

1

8

High-throughput

0.407

High

560756

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.298

High

560691

NPR3
Nitrogen permease regulator 3

1

0

High-throughput

0.279

Low

560692

DOG1
2-deoxyglucose-6-phosphate phosphatase 1

1

0

High-throughput

0.279

Low

560703

NPR2
Nitrogen permease regulator 2

1

0

High-throughput

0.279

Low

560648

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.261

Low

560714

YRB2
Ran-specific GTPase-activating protein 2

1

0

High-throughput

0.261

Low

560724

VPS55
Vacuolar protein sorting-associated protein 55

1

0

High-throughput

0.261

Low

560739

ZRG17
Protein ZRG17

1

0

High-throughput

0.261

Low

560763

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.261

Low

383476

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

454830

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

560226

TOP3
DNA topoisomerase 3

1

0

High-throughput

0.249

Low

560652

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

560675

SEF1
Putative transcription factor SEF1

1

0

High-throughput

0.249

Low

560716

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025