Protein: HEK2
Heterogeneous nuclear rnp K-like protein 2 (KH domain-containing protein 1)

Gene: HEK2
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: P38199

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0000932 - P-body
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

453940

IF4E
Eukaryotic translation initiation factor 4E

2

1

High-throughput

0.621

High

478611

IF2B
Eukaryotic translation initiation factor 2 subunit beta

2

1

High-throughput

0.621

High

666442

DBP2
ATP-dependent RNA helicase DBP2

2

18

High-throughput

0.621

High

751385

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

1

High-throughput

0.621

High

795764

IF4F2
Eukaryotic initiation factor 4F subunit p130

2

17

High-throughput

0.621

High

438678

SC160
Protein SCP160

1

18

High-throughput

0.618

High

656439

KC11
Casein kinase I homolog 1

2

4

Small-scale

0.602

High

795761

STM1
Suppressor protein STM1

2

0

High-throughput

0.595

High

795783

NAB6
RNA-binding protein NAB6

2

0

High-throughput

0.595

High

795786

YM91
Putative methyltransferase YMR310C

2

0

High-throughput

0.595

High

382052

H4
Histone H4

2

4

High-throughput

0.588

High

757478

NCBP1
Nuclear cap-binding protein complex subunit 1

2

5

High-throughput

0.588

High

795763

IF4F1
Eukaryotic initiation factor 4F subunit p150

2

8

High-throughput

0.588

High

795787

RRP5
rRNA biogenesis protein RRP5

1

12

High-throughput

0.575

High

544616

SSB1
Ribosome-associated molecular chaperone SSB1

2

11

High-throughput

0.552

High

403482

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

20

High-throughput

0.536

High

503379

RL11A
Large ribosomal subunit protein uL5A

1

4

High-throughput

0.536

High

645394

XRN1
5'-3' exoribonuclease 1

1

7

High-throughput

0.536

High

795760

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

4

High-throughput

0.536

High

795777

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

4

High-throughput

0.536

High

795793

RL7B
Large ribosomal subunit protein uL30B

1

3

High-throughput

0.536

High

795767

MLP2
Protein MLP2

2

9

Small-scale

0.533

High

795772

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.515

High

795773

ARC1
tRNA-aminoacylation cofactor ARC1

1

1

High-throughput

0.515

High

602421

PHO85
Cyclin-dependent protein kinase PHO85

1

11

High-throughput

0.501

High

795778

UBC9
SUMO-conjugating enzyme UBC9

1

3

Small-scale

0.501

High

795779

ATG1
Serine/threonine-protein kinase ATG1

1

5

High-throughput

0.501

High

795796

YL363
Uncharacterized protein YLR363W-A

1

0

High-throughput

0.493

High

154157

RL36B
Large ribosomal subunit protein eL36B

1

1

High-throughput

0.489

High

383663

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.489

High

511781

RS24A
Small ribosomal subunit protein eS24A

1

1

High-throughput

0.489

High

795766

RL13B
Large ribosomal subunit protein eL13B

1

4

High-throughput

0.489

High

795781

AP1M1
AP-1 complex subunit mu-1-I

1

2

High-throughput

0.489

High

795785

VPS20
Vacuolar protein sorting-associated protein 20

1

10

High-throughput

0.481

High

381082

H2B1
Histone H2B.1

1

6

High-throughput

0.479

High

381499

H2B2
Histone H2B.2

1

6

High-throughput

0.479

High

419412

H2A1
Histone H2A.1

1

5

High-throughput

0.479

High

419709

H2A2
Histone H2A.2

1

5

High-throughput

0.479

High

512062

RS4A
Small ribosomal subunit protein eS4A

1

6

High-throughput

0.479

High

518270

IF4A
ATP-dependent RNA helicase eIF4A

1

20

High-throughput

0.479

High

706898

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

740895

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

20

High-throughput

0.479

High

792005

GBLP
Small ribosomal subunit protein RACK1

1

17

Small-scale

0.479

High

795304

ATG8
Autophagy-related protein 8

1

20

High-throughput

0.479

High

795780

H3
Histone H3

1

6

High-throughput

0.479

High

795782

TOM1
E3 ubiquitin-protein ligase TOM1

1

17

High-throughput

0.479

High

795784

SCC2
Sister chromatid cohesion protein 2

1

3

High-throughput

0.479

High

795789

NCBP2
Nuclear cap-binding protein subunit 2

1

20

Small-scale

0.479

High

795791

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

795792

RIO1
Serine/threonine-protein kinase RIO1

1

5

High-throughput

0.479

High

795794

CMR1
DNA damage-binding protein CMR1

1

14

High-throughput

0.479

High

594337

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

795768

TM108
Protein TMA108

1

0

High-throughput

0.458

High

795788

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

795790

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

394484

EF1A
Elongation factor 1-alpha

1

10

High-throughput

0.445

High

427244

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.445

High

441867

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.445

High

444496

DED1
ATP-dependent RNA helicase DED1

1

18

High-throughput

0.445

High

453556

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.445

High

510426

HSP77
Import motor subunit, mitochondrial

1

12

High-throughput

0.445

High

523724

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

531709

RL4A
Large ribosomal subunit protein uL4A

1

4

High-throughput

0.445

High

569767

RL30
Large ribosomal subunit protein eL30

1

4

High-throughput

0.445

High

742830

HSP79
Heat shock protein homolog SSE2

1

13

High-throughput

0.445

High

795765

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

795769

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.445

High

795775

TCPQ
T-complex protein 1 subunit theta

1

6

High-throughput

0.445

High

795776

RL4B
Large ribosomal subunit protein uL4B

1

4

High-throughput

0.445

High

795795

SET6
Potential protein lysine methyltransferase SET6

1

1

High-throughput

0.445

High

795770

YPI1
Type 1 phosphatases regulator YPI1

1

0

High-throughput

0.438

High

512401

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.437

High

512966

RS8A
Small ribosomal subunit protein eS8A

1

4

High-throughput

0.437

High

513852

RS11B
Small ribosomal subunit protein uS17B

1

1

High-throughput

0.437

High

410084

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.407

High

503002

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.407

High

570241

RS17B
Small ribosomal subunit protein eS17B

1

2

High-throughput

0.407

High

689410

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.407

High

753327

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.407

High

482006

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

2

0

High-throughput

0.324

High

554603

RM02
Large ribosomal subunit protein bL27m

2

0

High-throughput

0.324

High

795762

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

795771

DCV1
Protein DCV1

1

0

High-throughput

0.238

Low

795774

RL17B
Large ribosomal subunit protein uL22B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025