Protein: SET6
Potential protein lysine methyltransferase SET6 (EC 2.1.1.-) (SET domain-containing protein 6)

Gene: SET6
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: Q12529

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0008168 - methyltransferase activity
GO:0032259 - methylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

382432

H4
Histone H4

1

3

High-throughput

0.575

High

525673

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.536

High

727434

HS104
Heat shock protein 104

2

0

High-throughput

0.528

High

810934

TCPG
T-complex protein 1 subunit gamma

2

1

High-throughput

0.504

High

393585

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.445

High

486373

TBA1
Tubulin alpha-1 chain

1

3

High-throughput

0.445

High

528121

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

546893

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

548741

RNA1
Ran GTPase-activating protein 1

1

1

High-throughput

0.445

High

652908

TRX2
Thioredoxin-2

1

1

High-throughput

0.445

High

737975

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.445

High

742767

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

751278

CNS1
Hsp70/Hsp90 co-chaperone CNS1

1

1

High-throughput

0.445

High

795795

HEK2
Heterogeneous nuclear rnp K-like protein 2

1

1

High-throughput

0.445

High

804590

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

806847

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.445

High

817994

IMB4
Importin subunit beta-4

1

1

High-throughput

0.445

High

948706

ACT
Actin

1

2

High-throughput

0.445

High

1053893

IMB1
Importin subunit beta-1

1

1

High-throughput

0.445

High

1059482

SUB2
ATP-dependent RNA helicase SUB2

1

1

High-throughput

0.445

High

1065626

NEW1
[NU+] prion formation protein 1

1

1

High-throughput

0.445

High

368264

TRP
Tryptophan synthase

1

0

High-throughput

0.426

High

488642

RIR2
Ribonucleoside-diphosphate reductase small chain 1

1

0

High-throughput

0.426

High

617960

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

0

High-throughput

0.426

High

632836

DBP5
ATP-dependent RNA helicase DBP5

1

0

High-throughput

0.426

High

638750

RIR1
Ribonucleoside-diphosphate reductase large chain 1

1

0

High-throughput

0.426

High

680193

CDC48
Cell division control protein 48

1

0

High-throughput

0.426

High

694676

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.426

High

710060

BMH1
Protein BMH1

1

0

High-throughput

0.426

High

871531

HGH1
Protein HGH1

1

0

High-throughput

0.426

High

1053602

RPN7
26S proteasome regulatory subunit RPN7

1

0

High-throughput

0.426

High

1084929

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.426

High

554075

TCPA
T-complex protein 1 subunit alpha

1

2

High-throughput

0.407

High

580310

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.407

High

605355

CAP
Adenylyl cyclase-associated protein

1

1

High-throughput

0.407

High

633587

SAR1
Small COPII coat GTPase SAR1

1

1

High-throughput

0.407

High

755201

GCN1
eIF-2-alpha kinase activator GCN1

1

1

High-throughput

0.407

High

760643

TSA1
Peroxiredoxin TSA1

1

1

High-throughput

0.407

High

779526

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.407

High

810796

TCPB
T-complex protein 1 subunit beta

1

3

High-throughput

0.407

High

811081

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.407

High

823670

TCPE
T-complex protein 1 subunit epsilon

1

3

High-throughput

0.407

High

844462

TCPH
T-complex protein 1 subunit eta

1

1

High-throughput

0.407

High

865126

TCPQ
T-complex protein 1 subunit theta

1

1

High-throughput

0.407

High

921477

SUCA
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial

1

1

High-throughput

0.407

High

386932

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

553674

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.232

Low

582529

SEC23
Protein transport protein SEC23

1

0

High-throughput

0.232

Low

599100

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.232

Low

603579

VATA
V-type proton ATPase catalytic subunit A

1

0

High-throughput

0.232

Low

618636

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.232

Low

618924

ARF2
ADP-ribosylation factor 2

1

0

High-throughput

0.232

Low

677829

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.232

Low

701755

URA7
CTP synthase 1

1

0

High-throughput

0.232

Low

726603

VATC
V-type proton ATPase subunit C

1

0

High-throughput

0.232

Low

732209

COPG
Coatomer subunit gamma

1

0

High-throughput

0.232

Low

737795

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

0

High-throughput

0.232

Low

743369

FIMB
Fimbrin

1

0

High-throughput

0.232

Low

796203

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.232

Low

811201

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

816760

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

825498

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

835973

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.232

Low

871457

HLJ1
Protein HLJ1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025