Protein: ZN131
Zinc finger protein 131

Gene: ZN131, ZNF131
Organism: Homo sapiens
Interactions: 120
UniProt ID: P52739

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001817 - regulation of cytokine production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

166508

BACH1
Transcription regulator protein BACH1

2

20

High-throughput

0.811

High

913802

ZBT18
Zinc finger and BTB domain-containing protein 18

2

19

High-throughput

0.811

High

913809

ZBTB3
Zinc finger and BTB domain-containing protein 3

2

19

High-throughput

0.789

High

913770

FHL2
Four and a half LIM domains protein 2

6

17

High-throughput

0.736

High

913778

FHL5
Four and a half LIM domains protein 5

5

17

High-throughput

0.717

High

913807

BACH2
Transcription regulator protein BACH2

1

19

High-throughput

0.691

High

913814

MBIP1
MAP3K12-binding inhibitory protein 1

3

0

High-throughput

0.638

High

913749

ZN131
Zinc finger protein 131

1

19

High-throughput

0.618

High

913767

CUL3
Cullin-3

1

20

High-throughput

0.618

High

913796

ZBT45
Zinc finger and BTB domain-containing protein 45

1

19

High-throughput

0.618

High

881500

CDK8
Cyclin-dependent kinase 8

2

3

High-throughput

0.611

High

913757

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

2

2

High-throughput

0.606

High

913815

RBM22
Pre-mRNA-splicing factor RBM22

1

0

High-throughput

0.586

High

129686

CBX4
E3 SUMO-protein ligase CBX4

2

20

Small-scale

0.584

High

913783

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

7

High-throughput

0.561

High

597347

GBB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

2

2

High-throughput

0.558

High

913787

MORN4
MORN repeat-containing protein 4

2

7

High-throughput

0.553

High

913751

MTPN
Myotrophin

1

3

High-throughput

0.553

High

210250

PHF1
PHD finger protein 1

1

1

High-throughput

0.536

High

593062

CREB1
Cyclic AMP-responsive element-binding protein 1

1

4

High-throughput

0.536

High

853946

KI67
Proliferation marker protein Ki-67

1

3

High-throughput

0.536

High

913761

KPCD
Protein kinase C delta type

1

2

High-throughput

0.536

High

913803

NPAS1
Neuronal PAS domain-containing protein 1

1

2

High-throughput

0.536

High

913804

FOXB1
Forkhead box protein B1

1

3

High-throughput

0.536

High

822546

VHL
von Hippel-Lindau disease tumor suppressor

1

2

High-throughput

0.515

High

890184

HINT1
Adenosine 5'-monophosphoramidase HINT1

1

0

High-throughput

0.513

High

913818

FOXJ2
Forkhead box protein J2

1

0

High-throughput

0.513

High

138658

IMA4
Importin subunit alpha-4

1

8

Small-scale

0.501

High

253604

IMA7
Importin subunit alpha-7

1

8

Small-scale

0.501

High

910820

IMA1
Importin subunit alpha-1

1

8

Small-scale

0.501

High

415450

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.494

High

258812

DNJA2
DnaJ homolog subfamily A member 2

1

7

High-throughput

0.479

High

273413

KDM4A
Lysine-specific demethylase 4A

1

4

High-throughput

0.479

High

274302

SIN3B
Paired amphipathic helix protein Sin3b

1

2

High-throughput

0.479

High

338792

CBX6
Chromobox protein homolog 6

1

20

High-throughput

0.479

High

339693

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

395739

ESR1
Estrogen receptor

1

18

Small-scale

0.479

High

405423

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.479

High

473871

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

520538

RARA
Retinoic acid receptor alpha

1

11

High-throughput

0.479

High

631632

RAB6A
Ras-related protein Rab-6A

1

1

High-throughput

0.479

High

667229

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.479

High

675426

TYY1
Transcriptional repressor protein YY1

1

18

High-throughput

0.479

High

679108

DNJB1
DnaJ homolog subfamily B member 1

1

7

High-throughput

0.479

High

697051

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

711803

KDM5A
Lysine-specific demethylase 5A

1

1

High-throughput

0.479

High

738960

ELF1
ETS-related transcription factor Elf-1

1

7

High-throughput

0.479

High

837028

ELK3
ETS domain-containing protein Elk-3

1

7

High-throughput

0.479

High

851475

GATA4
Transcription factor GATA-4

1

1

High-throughput

0.479

High

886662

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.479

High

913750

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

913756

H31
Histone H3.1

1

13

High-throughput

0.479

High

913758

H33
Histone H3.3

1

13

High-throughput

0.479

High

913759

RUNX1
Runt-related transcription factor 1

1

1

High-throughput

0.479

High

913760

KMT2A
Histone-lysine N-methyltransferase 2A

1

13

High-throughput

0.479

High

913763

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

913765

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

913766

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

2

High-throughput

0.479

High

913768

KLF9
Krueppel-like factor 9

1

20

High-throughput

0.479

High

913769

NFYC
Nuclear transcription factor Y subunit gamma

1

2

High-throughput

0.479

High

913772

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

913774

MO4L2
Mortality factor 4-like protein 2

1

2

Small-scale

0.479

High

913775

ELF2
ETS-related transcription factor Elf-2

1

5

High-throughput

0.479

High

913777

ZMYM1
Zinc finger MYM-type protein 1

1

13

High-throughput

0.479

High

913781

PWP2B
PWWP domain-containing protein 2B

1

3

High-throughput

0.479

High

913785

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

913788

PHC3
Polyhomeotic-like protein 3

1

2

High-throughput

0.479

High

913789

NUP43
Nucleoporin Nup43

1

4

High-throughput

0.479

High

913794

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

4

High-throughput

0.479

High

913795

SENP5
Sentrin-specific protease 5

1

3

High-throughput

0.479

High

913798

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

6

Small-scale

0.479

High

913799

PHF12
PHD finger protein 12

1

20

High-throughput

0.479

High

913800

RING2
E3 ubiquitin-protein ligase RING2

1

17

High-throughput

0.479

High

913801

FEV
Protein FEV

1

7

High-throughput

0.479

High

913806

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.479

High

913810

XPO5
Exportin-5

1

12

High-throughput

0.479

High

913813

RAB6B
Ras-related protein Rab-6B

1

1

High-throughput

0.479

High

913816

NHP2
H/ACA ribonucleoprotein complex subunit 2

1

7

High-throughput

0.479

High

913819

MO4L1
Mortality factor 4-like protein 1

1

2

Small-scale

0.479

High

913820

ZMYM2
Zinc finger MYM-type protein 2

1

11

High-throughput

0.479

High

913822

KMT2B
Histone-lysine N-methyltransferase 2B

1

10

High-throughput

0.479

High

913823

ZN281
Zinc finger protein 281

1

19

High-throughput

0.479

High

913824

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

913825

HCFC2
Host cell factor 2

1

2

High-throughput

0.479

High

156125

TRAD1
TRAF-type zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

215055

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

0

High-throughput

0.458

High

519351

MYB
Transcriptional activator Myb

1

0

High-throughput

0.458

High

840651

RS27
Small ribosomal subunit protein eS27

1

0

High-throughput

0.458

High

913753

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.458

High

913782

RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B

1

0

High-throughput

0.458

High

913784

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

913790

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

913805

NTM1A
N-terminal Xaa-Pro-Lys N-methyltransferase 1

1

0

High-throughput

0.458

High

913808

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.458

High

913812

EXOS3
Exosome complex component RRP40

1

0

High-throughput

0.458

High

913817

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

913791

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

Small-scale

0.445

High

353132

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

480747

LEG1
Galectin-1

1

1

High-throughput

0.437

High

821080

TXLNA
Alpha-taxilin

1

4

High-throughput

0.437

High

913754

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.437

High

913755

TPM4
Tropomyosin alpha-4 chain

1

1

High-throughput

0.437

High

913771

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

20

High-throughput

0.437

High

913793

NSUN4
5-cytosine rRNA methyltransferase NSUN4

1

9

High-throughput

0.437

High

913797

TIGD1
Tigger transposable element-derived protein 1

1

11

High-throughput

0.437

High

913821

MRM2
rRNA methyltransferase 2, mitochondrial

1

3

High-throughput

0.437

High

913811

MRM3
rRNA methyltransferase 3, mitochondrial

3

0

High-throughput

0.347

High

335380

GDF11
Growth/differentiation factor 11

1

0

High-throughput

0.279

Low

913780

PDE12
2',5'-phosphodiesterase 12

1

0

High-throughput

0.279

Low

75928

B4DEF8
Large ribosomal subunit protein mL45

1

0

High-throughput

0.249

Low

186454

INP4B
Inositol polyphosphate 4-phosphatase type II

1

0

High-throughput

0.249

Low

913752

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.249

Low

913762

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.249

Low

913764

RM28
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.249

Low

913773

RB39A
Ras-related protein Rab-39A

1

0

High-throughput

0.249

Low

913776

BLTP1
Bridge-like lipid transfer protein family member 1

1

0

High-throughput

0.249

Low

913779

FBX31
F-box only protein 31

1

0

High-throughput

0.249

Low

913786

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.249

Low

913792

NEUG
Neurogranin

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025