Protein: DHRS3
Short-chain dehydrogenase/reductase 3 (EC 1.1.1.300) (DD83.1) (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) (Retinol dehydrogenase 17) (Short chain dehydrogenase/reductase family 16C member 1)

Gene: DHRS3
Organism: Homo sapiens
Interactions: 40
UniProt ID: O75911

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0001523 - retinoid metabolic process
GO:0003151 - outflow tract morphogenesis
GO:0004745 - all-trans-retinol dehydrogenase (NAD+) activity
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

297071

DHRS4
Dehydrogenase/reductase SDR family member 4

1

17

High-throughput

0.691

High

252272

TLR5
Toll-like receptor 5

2

3

High-throughput

0.574

High

297075

C5AR2
C5a anaphylatoxin chemotactic receptor 2

2

3

High-throughput

0.574

High

297044

RASH
GTPase HRas

1

7

High-throughput

0.536

High

297045

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

1

High-throughput

0.536

High

297051

COPB2
Coatomer subunit beta'

1

7

High-throughput

0.536

High

297055

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

2

High-throughput

0.536

High

297069

ZDH12
Palmitoyltransferase ZDHHC12

1

2

High-throughput

0.536

High

297048

CD59
CD59 glycoprotein

1

0

High-throughput

0.513

High

297074

HINT3
Adenosine 5'-monophosphoramidase HINT3

1

0

High-throughput

0.513

High

248460

O10H2
Olfactory receptor 10H2

1

1

High-throughput

0.489

High

297050

IL4RA
Interleukin-4 receptor subunit alpha

1

2

High-throughput

0.489

High

297059

TTMP
TPA-induced transmembrane protein

1

2

High-throughput

0.489

High

297061

I22R1
Interleukin-22 receptor subunit alpha-1

1

2

High-throughput

0.489

High

297062

CCYL1
Cyclin-Y-like protein 1

1

1

High-throughput

0.489

High

297064

SIDT2
SID1 transmembrane family member 2

1

1

High-throughput

0.489

High

297065

CCNY
Cyclin-Y

1

1

High-throughput

0.489

High

297068

ARL8A
ADP-ribosylation factor-like protein 8A

1

6

High-throughput

0.489

High

297070

FEM1A
Protein fem-1 homolog A

1

2

High-throughput

0.489

High

297072

S22A4
Solute carrier family 22 member 4

1

2

High-throughput

0.489

High

297076

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

2

High-throughput

0.489

High

297079

PCDGE
Protocadherin gamma-B2

1

8

High-throughput

0.489

High

297080

PTC2
Protein patched homolog 2

1

2

High-throughput

0.489

High

297077

PDIP2
Polymerase delta-interacting protein 2

1

1

High-throughput

0.470

High

297046

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.437

High

297052

EAA2
Excitatory amino acid transporter 2

1

3

High-throughput

0.407

High

297057

S39AE
Metal cation symporter ZIP14

1

4

High-throughput

0.407

High

297067

CTL1
Choline transporter-like protein 1

1

1

High-throughput

0.407

High

297054

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.328

High

297063

I17RC
Interleukin-17 receptor C

2

0

High-throughput

0.328

High

297043

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.279

Low

297047

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.279

Low

297049

NEUM
Neuromodulin

1

0

High-throughput

0.279

Low

297053

GBG4

1

0

High-throughput

0.279

Low

297056

PLSI
Plastin-1

1

0

High-throughput

0.279

Low

297058

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.279

Low

297066

OCC1
Overexpressed in colon carcinoma 1 protein

1

0

High-throughput

0.279

Low

297073

CYTM1
Cysteine-rich and transmembrane domain-containing protein 1

1

0

High-throughput

0.279

Low

297060

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.249

Low

297078

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025