Protein: PEDF
Pigment epithelium-derived factor (PEDF) (Cell proliferation-inducing gene 35 protein) (EPC-1) (Serpin F1)

Gene: PEDF, SERPINF1
Organism: Homo sapiens
Interactions: 38
UniProt ID: P36955

Gene Ontology (top 5):
GO:0001822 - kidney development
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0005604 - basement membrane
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

467314

CBG
Corticosteroid-binding globulin

2

11

High-throughput

0.789

High

437635

HEPS
Serine protease hepsin

1

20

High-throughput

0.691

High

787843

ST14
Suppressor of tumorigenicity 14 protein

1

20

High-throughput

0.691

High

787829

LMBL2
Lethal(3)malignant brain tumor-like protein 2

3

2

High-throughput

0.662

High

287531

LRP6
Low-density lipoprotein receptor-related protein 6

1

2

Small-scale

0.647

High

534724

BIP
Endoplasmic reticulum chaperone BiP

2

15

High-throughput

0.628

High

787837

TMPSD
Transmembrane protease serine 13

1

20

High-throughput

0.618

High

787828

TMM25
Transmembrane protein 25

2

0

High-throughput

0.585

High

787831

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

6

High-throughput

0.553

High

518816

CCL3
C-C motif chemokine 3

1

1

High-throughput

0.536

High

529236

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.536

High

787821

TBA4A
Tubulin alpha-4A chain

1

4

High-throughput

0.536

High

787826

AMTN
Amelotin

1

2

High-throughput

0.536

High

787834

MMP19
Matrix metalloproteinase-19

1

4

High-throughput

0.536

High

787823

SG2A2
Mammaglobin-A

1

0

High-throughput

0.513

High

787832

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.513

High

778029

VGFR2
Vascular endothelial growth factor receptor 2

1

7

Small-scale

0.501

High

787833

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

1

High-throughput

0.501

High

463913

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

14

High-throughput

0.500

High

787822

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

1

High-throughput

0.494

High

593295

PGFRA
Platelet-derived growth factor receptor alpha

1

10

High-throughput

0.489

High

787825

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

9

High-throughput

0.489

High

787835

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

11

High-throughput

0.489

High

787838

MBNL1
Muscleblind-like protein 1

1

6

High-throughput

0.489

High

787841

PHF11
PHD finger protein 11

1

11

High-throughput

0.489

High

787842

SSUH2
Protein SSUH2 homolog

1

9

High-throughput

0.489

High

787836

MYOC
Myocilin

1

4

Small-scale

0.481

High

550897

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.479

High

384123

CO1A1
Collagen alpha-1(I) chain

1

5

High-throughput

0.445

High

360713

COX3
Cytochrome c oxidase subunit 3

1

3

Small-scale

0.437

High

787819

SOX2
Transcription factor SOX-2

1

12

High-throughput

0.437

High

787820

WDR5
WD repeat-containing protein 5

1

5

High-throughput

0.437

High

787827

EPMIP
EPM2A-interacting protein 1

5

0

High-throughput

0.378

High

787839

KLHL8
Kelch-like protein 8

2

0

High-throughput

0.328

High

787830

PLPL2
Patatin-like phospholipase domain-containing protein 2

2

0

Small-scale

0.320

High

787840

IMPCT
Protein IMPACT

2

0

High-throughput

0.316

High

787824

BAAT
Bile acid-CoA:amino acid N-acyltransferase

1

0

High-throughput

0.279

Low

787818

MLH1
DNA mismatch repair protein Mlh1

1

0

Small-scale

0.265

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025