Protein: SKY1
Serine/threonine-protein kinase SKY1 (SRPK) (EC 2.7.11.1)

Gene: SKY1
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: Q03656

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1031039

NOP3
Serine/arginine

7

20

Small-scale

0.963

High

676768

GBP2
Serine/arginine

2

20

Small-scale

0.812

High

807691

HRB1
Serine/arginine

2

20

Small-scale

0.799

High

524995

HSP71
Heat shock protein SSA1

4

19

High-throughput

0.672

High

548923

SCH9
Serine/threonine-protein kinase SCH9

1

20

High-throughput

0.647

High

584387

GCN2
eIF-2-alpha kinase GCN2

1

17

High-throughput

0.647

High

672202

KIN82
Serine/threonine-protein kinase KIN82

1

20

High-throughput

0.647

High

709455

HRR25
Casein kinase I homolog HRR25

1

17

High-throughput

0.647

High

740215

RPN2
26S proteasome regulatory subunit RPN2

1

9

High-throughput

0.647

High

925347

CRZ1
Transcriptional regulator CRZ1

1

7

High-throughput

0.647

High

1043534

VHS1
Serine/threonine-protein kinase VHS1

1

10

High-throughput

0.647

High

1043547

RTK1
Probable serine/threonine-protein kinase RTK1

1

19

High-throughput

0.647

High

1043550

PUF2
mRNA-binding protein PUF2

1

10

High-throughput

0.647

High

1043551

ARP8
Actin-like protein ARP8

1

14

High-throughput

0.647

High

736132

ARP2
Actin-related protein 2

1

12

Small-scale

0.621

High

850469

LSB3
LAS seventeen-binding protein 3

2

17

High-throughput

0.619

High

741091

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

20

High-throughput

0.618

High

924366

MDG1
Signal transduction protein MDG1

1

0

High-throughput

0.614

High

1043549

RIO1
Serine/threonine-protein kinase RIO1

1

3

Small-scale

0.552

High

750888

PRS6B
26S proteasome regulatory subunit 6B homolog

1

7

Small-scale

0.541

High

722218

XPO1
Exportin-1

1

14

High-throughput

0.536

High

762866

TOR1
Serine/threonine-protein kinase TOR1

1

17

High-throughput

0.536

High

1043548

BBP
Branchpoint-bridging protein

1

7

High-throughput

0.536

High

780853

MUD2
Splicing factor MUD2

1

0

High-throughput

0.513

High

416280

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

3

High-throughput

0.501

High

504672

YL21A
Transposon Ty2-LR1 Gag polyprotein

1

2

High-throughput

0.501

High

617869

DDR48
Stress protein DDR48

1

2

High-throughput

0.501

High

632728

DBP4
ATP-dependent RNA helicase HCA4

1

20

High-throughput

0.501

High

633228

KICH
Choline kinase

1

1

High-throughput

0.501

High

666539

DBP2
ATP-dependent RNA helicase DBP2

1

17

High-throughput

0.501

High

721411

MCM4
DNA replication licensing factor MCM4

1

15

High-throughput

0.501

High

746666

DRS1
ATP-dependent RNA helicase DRS1

1

20

High-throughput

0.501

High

751275

CNS1
Hsp70/Hsp90 co-chaperone CNS1

1

7

High-throughput

0.501

High

782271

DRE2
Fe-S cluster assembly protein DRE2

1

1

High-throughput

0.501

High

805137

YNG2
Chromatin modification-related protein YNG2

1

7

High-throughput

0.501

High

815557

RSP5
E3 ubiquitin-protein ligase RSP5

1

19

High-throughput

0.501

High

824697

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

14

High-throughput

0.501

High

858289

ARC1
tRNA-aminoacylation cofactor ARC1

1

5

High-throughput

0.501

High

864273

ALY2
Arrestin-related trafficking adapter 3

1

5

High-throughput

0.501

High

866139

JHD2
Histone demethylase JHD2

1

3

High-throughput

0.501

High

893292

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

20

High-throughput

0.501

High

924184

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

17

High-throughput

0.501

High

1043537

YM04
Abasic site processing protein YMR114C

1

1

High-throughput

0.501

High

1043538

YM11A
Transposon Ty1-ML1 Gag polyprotein

1

2

High-throughput

0.501

High

1043539

DBP9
ATP-dependent RNA helicase DBP9

1

20

High-throughput

0.501

High

1043541

RRP44
Exosome complex exonuclease DIS3

1

1

High-throughput

0.501

High

1043552

YI31B
Transposon Ty3-I Gag-Pol polyprotein

1

2

High-throughput

0.501

High

818191

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

3

High-throughput

0.489

High

470191

MET2
Homoserine O-acetyltransferase

1

0

High-throughput

0.480

High

724323

PUS3
tRNA pseudouridine(38/39) synthase

1

0

High-throughput

0.480

High

745494

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.480

High

781119

YKC3
Uncharacterized protein YKL023W

1

0

High-throughput

0.480

High

803329

YAP3
AP-1-like transcription factor YAP3

1

0

High-throughput

0.480

High

809403

STM1
Suppressor protein STM1

1

0

High-throughput

0.480

High

820888

SIP5
Protein SIP5

1

0

High-throughput

0.480

High

825553

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.480

High

1040442

UME1
Transcriptional regulatory protein UME1

1

0

High-throughput

0.480

High

1043540

CSA1
CDC5 pindle pole body anchor protein 1

1

0

High-throughput

0.480

High

1043542

VHS3
Phosphopantothenoylcysteine decarboxylase subunit VHS3

1

0

High-throughput

0.480

High

1043545

AB140
tRNA(Thr)

1

0

High-throughput

0.480

High

680016

CDC48
Cell division control protein 48

1

7

High-throughput

0.479

High

708040

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

764147

SPT21
Protein SPT21

1

1

High-throughput

0.479

High

909504

HFM1
ATP-dependent DNA helicase MER3

1

20

Small-scale

0.479

High

1042215

TOM1
E3 ubiquitin-protein ligase TOM1

1

19

High-throughput

0.479

High

1043535

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

1043536

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

585359

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

5

Small-scale

0.457

High

780533

AVT3
Vacuolar amino acid transporter 3

1

3

High-throughput

0.457

High

817483

VTC1
Vacuolar transporter chaperone complex subunit 1

1

1

High-throughput

0.457

High

850343

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

20

High-throughput

0.457

High

916835

MALX3
Oligo-1,6-glucosidase IMA1

1

4

High-throughput

0.457

High

1035364

FOX2
Peroxisomal hydratase-dehydrogenase-epimerase

1

3

High-throughput

0.457

High

825629

AIR1
Protein AIR1

1

6

High-throughput

0.457

High

917057

MCM6
DNA replication licensing factor MCM6

1

18

High-throughput

0.457

High

527555

HSP72
Heat shock protein SSA2

1

20

High-throughput

0.445

High

546092

SSB1
Ribosome-associated molecular chaperone SSB1

1

18

High-throughput

0.445

High

819660

SSB2
Ribosome-associated molecular chaperone SSB2

1

18

High-throughput

0.445

High

805040

SDO1L
Restriction of telomere capping protein 3

1

0

High-throughput

0.438

High

1043544

MPC54
Meiotic plaque component protein 54

1

0

High-throughput

0.438

High

803056

MUP3
Low-affinity methionine permease

1

4

High-throughput

0.437

High

1043546

AP3D
AP-3 complex subunit delta

1

11

High-throughput

0.437

High

776416

MNR2
Manganese resistance protein MNR2

1

0

High-throughput

0.261

Low

1043543

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025