Protein: MED9
Mediator of RNA polymerase II transcription subunit 9 (Chromosome segregation protein 2) (Mediator complex subunit 9)

Gene: MED9, CSE2
Organism: Saccharomyces cerevisiae S288C
Interactions: 53
UniProt ID: P33308

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003713 - transcription coactivator activity
GO:0005198 - structural molecule activity
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

751223

MED4
Mediator of RNA polymerase II transcription subunit 4

10

0

Small-scale

0.925

High

751222

MED1
Mediator of RNA polymerase II transcription subunit 1

7

0

Small-scale

0.910

High

751218

MED7
Mediator of RNA polymerase II transcription subunit 7

9

0

Small-scale

0.720

High

740391

MED17
Mediator of RNA polymerase II transcription subunit 17

9

0

Small-scale

0.717

High

751214

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

Small-scale

0.716

High

619411

MED14
Mediator of RNA polymerase II transcription subunit 14

8

0

Small-scale

0.714

High

740784

MED18
Mediator of RNA polymerase II transcription subunit 18

8

0

Small-scale

0.714

High

740449

MED22
Mediator of RNA polymerase II transcription subunit 22

6

0

Small-scale

0.696

High

668476

MED19
Mediator of RNA polymerase II transcription subunit 19

6

0

Small-scale

0.694

High

751204

MED8
Mediator of RNA polymerase II transcription subunit 8

6

0

Small-scale

0.691

High

751220

MED2
Mediator of RNA polymerase II transcription subunit 2

6

0

Small-scale

0.691

High

751215

MED5
Mediator of RNA polymerase II transcription subunit 5

4

0

Small-scale

0.661

High

624887

MED15
Mediator of RNA polymerase II transcription subunit 15

4

0

Small-scale

0.653

High

751217

MED10
Mediator of RNA polymerase II transcription subunit 10

4

0

Small-scale

0.653

High

751208

SSN3
Meiotic mRNA stability protein kinase SSN3

3

1

Small-scale

0.650

High

751206

MED6
Mediator of RNA polymerase II transcription subunit 6

4

0

Small-scale

0.648

High

751224

MED11
Mediator of RNA polymerase II transcription subunit 11

4

0

Small-scale

0.648

High

733530

MED16
Mediator of RNA polymerase II transcription subunit 16

3

0

Small-scale

0.622

High

751199

MED20
Mediator of RNA polymerase II transcription subunit 20

3

0

Small-scale

0.622

High

751210

MED3
Mediator of RNA polymerase II transcription subunit 3

3

0

Small-scale

0.622

High

751205

MED31
Mediator of RNA polymerase II transcription subunit 31

3

0

High-throughput

0.620

High

594284

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

0

Small-scale

0.613

High

706645

TF2B
Transcription initiation factor IIB

2

0

Small-scale

0.559

High

453922

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.513

High

751216

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

0

High-throughput

0.493

High

408468

GAL80
Galactose/lactose metabolism regulatory protein GAL80

1

0

High-throughput

0.486

High

381992

H4
Histone H4

1

0

Small-scale

0.480

High

602381

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

368634

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.479

High

607745

HXKG
Glucokinase-1

1

0

High-throughput

0.479

High

699394

CIN8
Kinesin-like protein CIN8

1

0

High-throughput

0.460

High

401949

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

470499

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

Small-scale

0.458

High

632073

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

Small-scale

0.458

High

678804

SRB8
Mediator of RNA polymerase II transcription subunit 12

1

0

High-throughput

0.458

High

751200

TAF14
Transcription initiation factor TFIID subunit 14

1

0

High-throughput

0.458

High

751201

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

751202

YKW2
Uncharacterized transcriptional regulatory protein YKL222C

1

0

High-throughput

0.458

High

751203

DPOA2
DNA polymerase alpha subunit B

1

0

High-throughput

0.458

High

751207

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.458

High

751212

T2FB
Transcription initiation factor IIF subunit beta

1

0

Small-scale

0.458

High

751213

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

0

High-throughput

0.458

High

751219

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

1

0

High-throughput

0.458

High

751221

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

523487

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526287

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

544314

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

553970

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.407

High

417064

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.279

Low

599663

STF2
ATPase-stabilizing factor 15 kDa protein

1

0

High-throughput

0.249

Low

751211

YIK8
Putative zinc metalloproteinase YIL108W

1

0

High-throughput

0.249

Low

751198

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

751209

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025