HitPredict

Interactor 1: TLR5 (O60602)
Toll-like receptor 5 (Toll/interleukin-1 receptor-like protein 3)
Gene: TLR5

Interactor 2: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.701

The method score is based on:

Property Details
Experiments 15107846, 16644730, 16482509, 20855887, 17583698
Identification Methods two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005149 - interleukin-1 receptor binding
GO:0005886 - plasma membrane
GO:0032757 - positive regulation of interleukin-8 production
GO:0045087 - innate immune response
GO:0071260 - cellular response to mechanical stimulus
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 858
Hs

1 296
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024