Interactor 1: CCNK (O75909)
Cyclin-K
Gene: CCNK
Interactor 2: CDK18 (Q07002)
Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)
Gene: CDK18
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.74 | 1.00 | 0.861 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16189514, 32296183, unassigned1304 |
| Identification Methods | two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cyclin_N~Pkinase, CycT2-like_C~Pkinase |
| Common GO terms | GO:0004693 - cyclin-dependent protein serine/threonine kinase activity GO:0005634 - nucleus |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
