HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.885

Property	Details
Experiments	28190767, 34642328, 36114200, 16196087
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 324
+	Hs
		475966 UBC_HUMAN (1-685): 0: 846: 100.00		CSN6_HUMAN (8-286): 1.73e-102: 305: 24.47
+	Hs
		124740 UBC_HUMAN (1-685): 0: 846: 100.00		EIF3F_HUMAN (2-279): 1.1e-98: 297: 26.88
+	Hs
		176926 UBC_HUMAN (1-685): 0: 846: 100.00		EIF3H_HUMAN (3-275): 1.64e-66: 214: 17.65
+	Hs
		476142 UBC_HUMAN (1-685): 0: 846: 100.00		CSN5_HUMAN (7-160): 1.07e-41: 149: 19.38
+	Sc
		477476 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		RPN8_YEAST (7-322): 1.4e-99: 298: 47.01
+	At
		188941 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSD7A_ARATH (1-289): 1.39e-106: 315: 61.03
+	At
		1091969 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSD7B_ARATH (1-289): 1.06e-105: 313: 59.66
+	At
		1091853 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		CSN6A_ARATH (2-290): 9e-90: 272: 22.22
+	At
		137953 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		EIF3F_ARATH (2-281): 4.43e-81: 249: 27.40
+	Mm
		476691 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PSMD7_MOUSE (1-285): 4.25e-110: 324: 99.30
+	At
		1091793 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		CSN5A_ARATH (7-161): 1.07e-49: 171: 19.88
+	Hs
		397853 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PSMD7_HUMAN (1-285): 5.24e-110: 324: 100.00
+	Rn
		89029 UBC_RAT (1-108): 1.27e-29: 127: 90.74		D4AEH3_RAT (1-285): 1.43e-103: 307: 96.14
+	Mm
		291863 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		CSN6_MOUSE (8-286): 1.4e-101: 303: 24.47
+	At
		1092172 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		PSDE_ARATH (7-142): 6.48e-31: 120: 26.76
+	Mm
		193512 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		CSN5_MOUSE (7-160): 9.31e-42: 149: 19.38
+	Mm
		192886 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PSDE_MOUSE (5-142): 6.8e-28: 112: 24.31