HitPredict

Interactor 1: K1C19 (P08727)
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)
Gene: KRT19

Interactor 2: K2C79 (Q5XKE5)
Keratin, type II cytoskeletal 79 (Cytokeratin-79) (CK-79) (Keratin-6-like) (Keratin-6L) (Keratin-79) (K79) (Type-II keratin Kb38)
Gene: KRT79

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	32296183, 35575683, unassigned1304
Identification Methods	two hybrid, cross-linking study, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005829 - cytosol GO:0045109 - intermediate filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 400 Hs			1 535
+	Hs
		475532 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K22E_HUMAN (114-460): 1.25e-156: 462: 70.03
+	Hs
		475501 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C7_HUMAN (89-469): 7.08e-142: 419: 62.69
+	Hs
		437062 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C8_HUMAN (114-492): 1.6e-141: 418: 61.48
+	Hs
		475621 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C73_HUMAN (18-533): 1.43e-93: 297: 53.83
+	Hs
		475559 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		KRT83_HUMAN (5-506): 8.77e-92: 291: 43.63
+	Hs
		475576 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		KRT81_HUMAN (13-514): 6.91e-91: 289: 44.02
+	Hs
		227200 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		KRT86_HUMAN (5-514): 1.06e-89: 285: 42.75
+	Hs
		341726 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C75_HUMAN (3-471): 1.45e-88: 284: 62.26
+	Hs
		475560 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		KRT85_HUMAN (2-509): 5.86e-88: 281: 44.49
+	Hs
		475615 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C1B_HUMAN (36-476): 1.42e-81: 267: 59.48
+	Hs
		475588 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C71_HUMAN (18-460): 1.3e-81: 265: 59.06
+	Hs
		475579 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C72_HUMAN (23-525): 5.49e-77: 253: 52.95
+	Hs
		407240 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C6B_HUMAN (3-481): 4.19e-76: 252: 62.87
+	Hs
		475542 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C6C_HUMAN (3-481): 9.22e-76: 251: 62.87
+	Hs
		475510 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C5_HUMAN (3-460): 1.46e-74: 249: 63.51
+	Hs
		475613 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C74_HUMAN (1-533): 6.21e-73: 243: 47.84
+	Hs
		385220 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C6A_HUMAN (3-481): 3.81e-72: 242: 61.88
+	Hs
		475516 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C4_HUMAN (5-476): 1.01e-68: 231: 63.10
+	Hs
		475506 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C3_HUMAN (114-461): 7.29e-64: 221: 73.85
+	Hs
		475561 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K22O_HUMAN (5-472): 3.77e-63: 219: 57.51