Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42
Interactor 2: ARHG3 (Q9NR81)
Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN)
Gene: ARHGEF3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.34 | 1.00 | 0.590 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21311754 |
| Identification Methods | two hybrid |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ras~RhoGEF, Ras~SOS1_NGEF_PH |
| Common GO terms | GO:0005829 - cytosol |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
