Protein: UBP48
Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48)

Gene: UBP48, USP48
Organism: Homo sapiens
Interactions: 137
UniProt ID: Q86UV5

Gene Ontology (top 5):
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475995

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

5

20

Small-scale

0.907

High

475082

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

3

20

Small-scale

0.861

High

1200179

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

2

17

Small-scale

0.776

High

1200174

WDR76
WD repeat-containing protein 76

2

16

Small-scale

0.754

High

934932

H31
Histone H3.1

4

10

Small-scale

0.676

High

420851

H2B1J
Histone H2B type 1-J

3

20

Small-scale

0.667

High

1140578

RN123
E3 ubiquitin-protein ligase RNF123

3

11

Small-scale

0.667

High

1192586

PXK
PX domain-containing protein kinase-like protein

3

8

Small-scale

0.667

High

1200172

UBAC1
Ubiquitin-associated domain-containing protein 1

3

4

Small-scale

0.667

High

1200180

ZN232
Zinc finger protein 232

3

6

Small-scale

0.667

High

978792

TF65
Transcription factor p65

3

8

Small-scale

0.664

High

1061348

NR1D2
Nuclear receptor subfamily 1 group D member 2

3

10

Small-scale

0.656

High

555529

H2AX
Histone H2AX

3

19

Small-scale

0.640

High

918483

H2B1C
Histone H2B type 1-C/E/F/G/I

3

20

Small-scale

0.640

High

1020772

TRAF2
TNF receptor-associated factor 2

3

20

Small-scale

0.640

High

1200159

SIR6
NAD-dependent protein deacylase sirtuin-6

3

13

Small-scale

0.640

High

1184751

NDUF7
Protein arginine methyltransferase NDUFAF7, mitochondrial

3

0

Small-scale

0.638

High

436726

GLI1
Zinc finger protein GLI1

2

10

Small-scale

0.624

High

1200155

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

13

Small-scale

0.618

High

1200165

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

9

High-throughput

0.618

High

395072

A4
Amyloid-beta precursor protein

2

5

Small-scale

0.595

High

934281

CSK21
Casein kinase II subunit alpha

2

8

Small-scale

0.595

High

1039658

SNW1
SNW domain-containing protein 1

2

0

Small-scale

0.585

High

260922

H2AY
Core histone macro-H2A.1

2

20

Small-scale

0.584

High

391769

H2A1B
Histone H2A type 1-B/E

2

17

Small-scale

0.584

High

470072

H2AZ
Histone H2A.Z

2

19

Small-scale

0.584

High

707674

H2B1B
Histone H2B type 1-B

2

20

Small-scale

0.584

High

781388

BCL6
B-cell lymphoma 6 protein

2

4

Small-scale

0.584

High

835860

GSK3B
Glycogen synthase kinase-3 beta

2

6

Small-scale

0.584

High

917521

H4
Histone H4

2

7

Small-scale

0.584

High

962847

MDM2
E3 ubiquitin-protein ligase Mdm2

2

9

Small-scale

0.584

High

1024181

CSN1
COP9 signalosome complex subunit 1

2

4

Small-scale

0.584

High

723740

DRD3
D(3) dopamine receptor

2

5

Small-scale

0.566

High

147173

FCHO1
F-BAR domain only protein 1

1

2

High-throughput

0.536

High

1200164

EFMT3
EEF1A lysine methyltransferase 3

1

4

High-throughput

0.536

High

1200169

FMNL2
Formin-like protein 2

1

1

High-throughput

0.536

High

385100

NTRK1
High affinity nerve growth factor receptor

2

8

Small-scale

0.533

High

822761

SL9A3
Sodium/hydrogen exchanger 3

2

1

Small-scale

0.533

High

1025823

TADBP
TAR DNA-binding protein 43

1

12

High-throughput

0.515

High

902655

SUMO2
Small ubiquitin-related modifier 2

1

3

High-throughput

0.501

High

180165

CCL16
C-C motif chemokine 16

1

2

High-throughput

0.489

High

1200160

ZCH10
Zinc finger CCHC domain-containing protein 10

1

1

High-throughput

0.489

High

48120

UBA6
Ubiquitin-like modifier-activating enzyme 6

1

3

Small-scale

0.479

High

117422

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

1

High-throughput

0.479

High

179706

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

7

High-throughput

0.479

High

205610

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

234345

GSDME
Gasdermin-E

1

1

Small-scale

0.479

High

244621

BRD4
Bromodomain-containing protein 4

1

14

High-throughput

0.479

High

342533

CAH1
Carbonic anhydrase 1

1

2

Small-scale

0.479

High

396759

S10A8
Protein S100-A8

1

9

Small-scale

0.479

High

416465

S10A9
Protein S100-A9

1

10

Small-scale

0.479

High

430243

PROF1
Profilin-1

1

3

Small-scale

0.479

High

448360

GSTP1
Glutathione S-transferase P

1

4

Small-scale

0.479

High

455606

PARP1
Poly [ADP-ribose] polymerase 1

1

9

High-throughput

0.479

High

487565

ANDR
Androgen receptor

1

16

High-throughput

0.479

High

540434

MMP9
Matrix metalloproteinase-9

1

3

Small-scale

0.479

High

548111

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

7

Small-scale

0.479

High

553087

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

559159

H15
Histone H1.5

1

8

Small-scale

0.479

High

559803

H12
Histone H1.2

1

7

Small-scale

0.479

High

621375

CMA1
Chymase

1

4

Small-scale

0.479

High

644084

EF1G
Elongation factor 1-gamma

1

6

High-throughput

0.479

High

651592

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

720827

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

739757

SRP14
Signal recognition particle 14 kDa protein

1

1

Small-scale

0.479

High

749636

BRCA1
Breast cancer type 1 susceptibility protein

1

14

Small-scale

0.479

High

759717

RS19
Small ribosomal subunit protein eS19

1

1

Small-scale

0.479

High

760150

RL3
Large ribosomal subunit protein uL3

1

2

Small-scale

0.479

High

799921

PPIC
Peptidyl-prolyl cis-trans isomerase C

1

2

Small-scale

0.479

High

805714

RL27A
Large ribosomal subunit protein uL15

1

1

Small-scale

0.479

High

828286

CENPA
Histone H3-like centromeric protein A

1

10

High-throughput

0.479

High

853935

NCBP2
Nuclear cap-binding protein subunit 2

1

8

Small-scale

0.479

High

868579

ATX1
Ataxin-1

1

4

High-throughput

0.479

High

908762

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

913611

RL7A
Large ribosomal subunit protein eL8

1

6

Small-scale

0.479

High

952442

H33
Histone H3.3

1

10

High-throughput

0.479

High

971245

H11
Histone H1.1

1

7

Small-scale

0.479

High

1034173

U119A
Protein unc-119 homolog A

1

1

High-throughput

0.479

High

1043436

CUL4B
Cullin-4B

1

11

Small-scale

0.479

High

1055412

DHX8
ATP-dependent RNA helicase DHX8

1

9

Small-scale

0.479

High

1087036

H2A2C
Histone H2A type 2-C

1

17

Small-scale

0.479

High

1135195

RBM26
RNA-binding protein 26

1

8

Small-scale

0.479

High

1187645

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

9

Small-scale

0.479

High

1199327

ZN329
Zinc finger protein 329

1

2

Small-scale

0.479

High

1200156

HTR5A
HEAT repeat-containing protein 5A

1

1

Small-scale

0.479

High

1200161

RAD50
DNA repair protein RAD50

1

17

High-throughput

0.479

High

1200166

AURKB
Aurora kinase B

1

13

Small-scale

0.479

High

1200170

VPS35
Vacuolar protein sorting-associated protein 35

1

1

Small-scale

0.479

High

1200173

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

1

9

Small-scale

0.479

High

1200175

CSN7B
COP9 signalosome complex subunit 7b

1

2

Small-scale

0.479

High

1200177

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

1

Small-scale

0.479

High

1200181

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

1200182

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

1

Small-scale

0.479

High

297869

SC24D
Protein transport protein Sec24D

1

0

Small-scale

0.458

High

336285

PH4H
Phenylalanine-4-hydroxylase

1

0

Small-scale

0.458

High

532155

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

Small-scale

0.458

High

542970

CBPA3
Mast cell carboxypeptidase A

1

0

Small-scale

0.458

High

549577

VEGFA
Vascular endothelial growth factor A, long form

1

0

Small-scale

0.458

High

554851

LOX15
Polyunsaturated fatty acid lipoxygenase ALOX15

1

0

Small-scale

0.458

High

584530

GGT1
Glutathione hydrolase 1 proenzyme

1

0

Small-scale

0.458

High

804134

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

0

Small-scale

0.458

High

1047561

RGRF1
Ras-specific guanine nucleotide-releasing factor 1

1

0

Small-scale

0.458

High

1120747

ACSM3
Acyl-coenzyme A synthetase ACSM3, mitochondrial

1

0

Small-scale

0.458

High

1131235

NU188
Nucleoporin NUP188

1

0

Small-scale

0.458

High

1162186

BRAT1
BRCA1-associated ATM activator 1

1

0

Small-scale

0.458

High

1200162

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1200178

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1200168

CEP63
Centrosomal protein of 63 kDa

1

20

High-throughput

0.457

High

347208

MYC
Myc proto-oncogene protein

1

14

High-throughput

0.445

High

1057524

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

5

High-throughput

0.445

High

1155943

Q6NSM0
NR1D2 protein

1

14

High-throughput

0.445

High

100910

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

341215

HPT
Haptoglobin

1

2

Small-scale

0.437

High

344121

ANT3
Antithrombin-III

1

4

Small-scale

0.437

High

358612

CO2A1
Collagen alpha-1(II) chain

1

1

Small-scale

0.437

High

389789

CY24B
Cytochrome b-245 heavy chain

1

1

Small-scale

0.437

High

392695

B3A2
Anion exchange protein 2

1

1

Small-scale

0.437

High

429323

SAP
Prosaposin

1

1

Small-scale

0.437

High

593887

PRVA
Parvalbumin alpha

1

1

Small-scale

0.437

High

795179

SSRA
Translocon-associated protein subunit alpha

1

1

Small-scale

0.437

High

839627

SERPH
Serpin H1

1

5

Small-scale

0.437

High

879411

FCGRN
IgG receptor FcRn large subunit p51

1

1

Small-scale

0.437

High

945690

NGAL
Neutrophil gelatinase-associated lipocalin

1

1

Small-scale

0.437

High

1017589

FSTL1
Follistatin-related protein 1

1

1

Small-scale

0.437

High

1079665

ADIPO
Adiponectin

1

3

Small-scale

0.437

High

1200163

FKB10
Peptidyl-prolyl cis-trans isomerase FKBP10

1

2

Small-scale

0.437

High

1200167

ZFR
Zinc finger RNA-binding protein

1

9

Small-scale

0.437

High

1200171

GBRG3
Gamma-aminobutyric acid receptor subunit gamma-3

1

2

Small-scale

0.437

High

1200176

DJC17
DnaJ homolog subfamily C member 17

1

9

High-throughput

0.437

High

402822

TETN
Tetranectin

1

0

Small-scale

0.249

Low

436989

DAF
Complement decay-accelerating factor

1

0

Small-scale

0.249

Low

532996

PRG2
Bone marrow proteoglycan

1

0

Small-scale

0.249

Low

709262

GALNS
N-acetylgalactosamine-6-sulfatase

1

0

Small-scale

0.249

Low

976236

UPAR
Urokinase plasminogen activator surface receptor

1

0

Small-scale

0.249

Low

1200157

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

Small-scale

0.249

Low

1200158

PROM2
Prominin-2

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024