Protein: DDHD1
Phospholipase DDHD1 (EC 3.1.1.111) (EC 3.1.1.32) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1) (EC 3.1.1.118) (Phospholipid sn-1 acylhydrolase)

Gene: DDHD1
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q8NEL9

Gene Ontology (top 5):
GO:0004620 - phospholipase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008970 - phospholipase A1 activity
GO:0046488 - phosphatidylinositol metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1337516

DYL2
Dynein light chain 2, cytoplasmic

3

1

High-throughput

0.662

High

170240

AURKA
Aurora kinase A

2

1

High-throughput

0.611

High

1180642

CR1L
Complement component receptor 1-like protein

2

1

High-throughput

0.606

High

991636

DYL1
Dynein light chain 1, cytoplasmic

2

1

High-throughput

0.601

High

138931

USP9Y
Ubiquitin carboxyl-terminal hydrolase 9Y

1

1

High-throughput

0.536

High

539615

PYGM
Glycogen phosphorylase, muscle form

1

1

High-throughput

0.536

High

163139

CHK1
Serine/threonine-protein kinase Chk1

1

0

High-throughput

0.513

High

1234697

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

1

0

High-throughput

0.513

High

1337513

PSMF1
Proteasome inhibitor PI31 subunit

1

0

High-throughput

0.513

High

1337514

MY18A
Unconventional myosin-XVIIIa

1

0

High-throughput

0.513

High

1337515

ISOC1
Isochorismatase domain-containing protein 1

1

0

High-throughput

0.513

High

1337518

KIF2C
Kinesin-like protein KIF2C

1

0

High-throughput

0.513

High

1337521

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.513

High

1337523

NJMU
Protein Njmu-R1

1

0

High-throughput

0.513

High

1337526

MTMR6
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6

1

0

High-throughput

0.513

High

181143

AXIN1
Axin-1

1

0

High-throughput

0.493

High

285693

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.493

High

242327

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

404235

GCR
Glucocorticoid receptor

1

3

High-throughput

0.479

High

422641

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.479

High

1314081

AMOL1
Angiomotin-like protein 1

1

0

High-throughput

0.458

High

1337520

CDAC1
Cytidine and dCMP deaminase domain-containing protein 1

1

0

High-throughput

0.458

High

1337522

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1323202

PDK1L
Serine/threonine-protein kinase PDIK1L

1

1

High-throughput

0.445

High

589195

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

1068849

IFFO1
Non-homologous end joining factor IFFO1

1

1

High-throughput

0.437

High

1219584

JKIP3
Janus kinase and microtubule-interacting protein 3

1

4

High-throughput

0.437

High

1337525

SCML1
Sex comb on midleg-like protein 1

1

1

High-throughput

0.437

High

911007

IMA1
Importin subunit alpha-1

1

0

High-throughput

0.426

High

1110508

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

0

High-throughput

0.426

High

1204375

SGO1
Shugoshin 1

1

0

High-throughput

0.426

High

1204710

TAF7L
Transcription initiation factor TFIID subunit 7-like

1

0

High-throughput

0.426

High

1063448

GOGA2
Golgin subfamily A member 2

1

2

High-throughput

0.407

High

208866

ZBT24
Zinc finger and BTB domain-containing protein 24

2

0

High-throughput

0.316

High

1225949

F91A1
Protein FAM91A1

1

0

High-throughput

0.279

Low

1257078

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.279

Low

1337524

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

0

High-throughput

0.279

Low

1200461

COBL1
Cordon-bleu protein-like 1

1

0

High-throughput

0.249

Low

827447

MLH1
DNA mismatch repair protein Mlh1

1

0

High-throughput

0.232

Low

1150453

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

0

High-throughput

0.232

Low

1177170

MICB
MHC class I polypeptide-related sequence B

1

0

High-throughput

0.232

Low

1337517

HMCES
Abasic site processing protein HMCES

1

0

High-throughput

0.232

Low

1337519

SOST
Sclerostin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025